Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Caitlyn L Holmes"'
Autor:
Harry L T Mobley, Mark T Anderson, Bridget S Moricz, Geoffrey B Severin, Caitlyn L Holmes, Elizabeth N Ottosen, Tad Eichler, Surbhi Gupta, Santosh Paudel, Ritam Sinha, Sophia Mason, Stephanie D Himpsl, Aric N Brown, Margaret Gaca, Christina M Kiser, Thomas H Clarke, Derrick E Fouts, Victor J DiRita, Michael A Bachman
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012495 (2024)
There is a critical gap in knowledge about how Gram-negative bacterial pathogens, using survival strategies developed for other niches, cause lethal bacteremia. Facultative anaerobic species of the Enterobacterales order are the most common cause of
Externí odkaz:
https://doaj.org/article/790cb40716724b9980c96102427a6fde
Autor:
Jay Vornhagen, Christine M Bassis, Srividya Ramakrishnan, Robert Hein, Sophia Mason, Yehudit Bergman, Nicole Sunshine, Yunfan Fan, Caitlyn L Holmes, Winston Timp, Michael C Schatz, Vincent B Young, Patricia J Simner, Michael A Bachman
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009537 (2021)
Klebsiella pneumoniae (Kp) is an important cause of healthcare-associated infections, which increases patient morbidity, mortality, and hospitalization costs. Gut colonization by Kp is consistently associated with subsequent Kp disease, and patients
Externí odkaz:
https://doaj.org/article/fa3d3e515da74a689ac27b6245f842d6
Autor:
Caitlyn L Holmes, Chloe G Peyton, Amy M Bier, Tobias Z Donlon, Fauzia Osman, Christie M Bartels, Miriam A Shelef
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217221 (2019)
BackgroundThe antibody response to pertussis vaccination in rheumatoid arthritis is unknown, a concerning omission given the relatively low efficacy of the pertussis vaccine, a rise in pertussis infections, and a general increased susceptibility to i
Externí odkaz:
https://doaj.org/article/fb2217ed988741beb7a8304b0d17e873
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAnti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis, but the sources of citrullinated antigens as well as which peptidylarginine deiminases (PADs) are required for their production remain incompletely defi
Externí odkaz:
https://doaj.org/article/775a57052f284fc39ce1d8353ef9387b
Autor:
Caitlyn L. Holmes
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTCaitlyn Holmes works in the field of bacterial pathogenesis and host-pathogen interactions. In this mSphere of Influence article, she reflects on how the papers “Innate Lymphocyte/Ly6Chi Monocyte Crosstalk Promotes Klebsiella pneumoniae Cle
Externí odkaz:
https://doaj.org/article/799fbcfdf2c64e2391336e2ea2473a51
Autor:
Jay Vornhagen, Emily K. Roberts, Lavinia Unverdorben, Sophia Mason, Alieysa Patel, Ryan Crawford, Caitlyn L. Holmes, Yuang Sun, Alexandra Teodorescu, Evan S. Snitkin, Lili Zhao, Patricia J. Simner, Pranita D. Tamma, Krishna Rao, Keith S. Kaye, Michael A. Bachman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Patient variables, such as comorbidities, partially explain which patients will progress to Klebsiella infection, with colonization of the gut acting as a reservoir. Little is known, however, regarding Klebsiella genes that may increase risk of disea
Externí odkaz:
https://doaj.org/article/9fca71bb880145e79855025ffb4001fa
Autor:
Caitlyn L. Holmes, Alexis E. Wilcox, Valerie Forsyth, Sara N. Smith, Bridget S. Moricz, Lavinia V. Unverdorben, Sophia Mason, Weisheng Wu, Lili Zhao, Harry L.T. Mobley, Michael A. Bachman
Gram-negative bacteremia is a major cause of global morbidity involving three phases of pathogenesis: initial site infection, dissemination, and survival in the blood and filtering organs.Klebsiella pneumoniaeis a leading cause of bacteremia and pneu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc723ee519b03c7c99766f1c5a4e095e
https://doi.org/10.1101/2023.02.23.529827
https://doi.org/10.1101/2023.02.23.529827
Autor:
Aisha M. Mergaert, Mandar Bawadekar, Thai Q. Nguyen, Laura Massarenti, Caitlyn L. Holmes, Ryan Rebernick, Steven J. Schrodi, Miriam A. Shelef
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3093 (2019)
Autoantibodies against citrullinated proteins are a hallmark of rheumatoid arthritis, a destructive inflammatory arthritis. Peptidylarginine deiminase 4 (PAD4) has been hypothesized to contribute to rheumatoid arthritis by citrullinating histones to
Externí odkaz:
https://doaj.org/article/6b929deed394480a8097cdd0c48eedb1
Autor:
Caitlyn L. Holmes, Sara N. Smith, Stephen J. Gurczynski, Geoffrey B. Severin, Lavinia V. Unverdorben, Jay Vornhagen, Harry L. T. Mobley, Michael A. Bachman
Klebsiella pneumoniae is a leading cause of Gram-negative bacteremia, which is a major source of morbidity and mortality worldwide. Gram-negative bacteremia requires three major steps: primary site infection, dissemination to the blood, and bloodstre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009949c7a80203d5390bb7af59e35883
https://doi.org/10.1101/2022.03.08.483568
https://doi.org/10.1101/2022.03.08.483568
Autor:
Caitlyn L. Holmes, Nicole Sunshine, Yehudit Bergman, Patricia J. Simner, Michael C. Schatz, Vincent B. Young, Jay Vornhagen, Srividya Ramakrishnan, Michael A. Bachman, Robert Hein, Yunfan Fan, Winston Timp, Christine M. Bassis, Sophia Mason
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 4, p e1009537 (2021)
PLoS Pathogens, Vol 17, Iss 4, p e1009537 (2021)
Klebsiella pneumoniae (Kp) is an important cause of healthcare-associated infections, which increases patient morbidity, mortality, and hospitalization costs. Gut colonization by Kp is consistently associated with subsequent Kp disease, and patients