Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Caitlin Walker"'
Autor:
Cristina Olivieri, Yingjie Wang, Caitlin Walker, Manu Veliparambil Subrahmanian, Kim N Ha, David Bernlohr, Jiali Gao, Carlo Camilloni, Michele Vendruscolo, Susan S Taylor, Gianluigi Veglia
Publikováno v:
eLife, Vol 12 (2024)
Allosteric cooperativity between ATP and substrates is a prominent characteristic of the cAMP-dependent catalytic subunit of protein kinase A (PKA-C). This long-range synergistic action is involved in substrate recognition and fidelity, and it may al
Externí odkaz:
https://doaj.org/article/97f7a7bc79034a6aaaaa8c648397a2b6
Autor:
Cristina Olivieri, Caitlin Walker, Adak Karamafrooz, Yingjie Wang, V. S. Manu, Fernando Porcelli, Donald K. Blumenthal, David D. Thomas, David A. Bernlohr, Simon M. Sandford, Susan S. Taylor, Gianluigi Veglia
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Olivieri, Walker, Karamafrooz et al. show that the fusion of the dynamic J-domain to PKA-C (PKA-CDNAJB1) disrupts the internal allosteric network, attenuating the nucleotide/PKI binding cooperativity. This study suggests that the reduced allosteric c
Externí odkaz:
https://doaj.org/article/43c1fcd3a0854b83a040ab4779192c9e
Autor:
Cristina Olivieri, Caitlin Walker, Adak Karamafrooz, Yingjie Wang, V. S. Manu, Fernando Porcelli, Donald K. Blumenthal, David D. Thomas, David A. Bernlohr, Sanford M. Simon, Susan S. Taylor, Gianluigi Veglia
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-02006-3
Externí odkaz:
https://doaj.org/article/7c24fd9db8f04d64a2a736102b658354
Autor:
Erik K. Larsen, Cristina Olivieri, Caitlin Walker, Manu V.S., Jiali Gao, David A. Bernlohr, Marco Tonelli, John L. Markley, Gianluigi Veglia
Publikováno v:
Molecules, Vol 23, Iss 8, p 1937 (2018)
Protein-protein interactions (PPIs) regulate a plethora of cellular processes and NMR spectroscopy has been a leading technique for characterizing them at the atomic resolution. Technically, however, PPIs characterization has been challenging due to
Externí odkaz:
https://doaj.org/article/9f27098cd6fd4467b12bbfd4bc44a176
Autor:
Cristina Olivieri, Caitlin Walker, Manu Veliparambil Subrahmanian, Fernando Porcelli, Susan S. Taylor, David A. Bernlohr, Gianluigi Veglia
Publikováno v:
FEBS Letters. 597:1055-1072
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd980f3fafb533e33cc864cdce1a6187
https://doi.org/10.1002/1873-3468.14610
https://doi.org/10.1002/1873-3468.14610
Autor:
Sumit Sen Santara, Dian-Jang Lee, Ângela Crespo, Jun Jacob Hu, Caitlin Walker, Xiyu Ma, Ying Zhang, Sourav Chowdhury, Karla F. Meza-Sosa, Mercedes Lewandrowski, Haiwei Zhang, Marjorie Rowe, Arthur McClelland, Hao Wu, Caroline Junqueira, Judy Lieberman
Publikováno v:
Nature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e062afc87a566094bd2015e8d439750
https://doi.org/10.1038/s41586-023-06151-z
https://doi.org/10.1038/s41586-023-06151-z
Autor:
Sumit Sen Santara, Dian-Jang Lee, Ângela Crespo, Jun Jacob Hu, Caitlin Walker, Xiyu Ma, Ying Zhang, Sourav Chowdhury, Karla F. Meza-Sosa, Mercedes Lewandrowski, Haiwei Zhang, Marjorie Rowe, Arthur McClelland, Hao Wu, Caroline Junqueira, Judy Lieberman
Publikováno v:
Nature
Natural killer (NK) cell kill infected, transformed and stressed cells when an activating NK cell receptor is triggered(1). Most NK cells and some innate lymphoid cells express the activating receptor NKp46, encoded by NCR1, the most evolutionarily a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7591556cc3a0d3d471d7b10282fa1e14
https://europepmc.org/articles/PMC10165876/
https://europepmc.org/articles/PMC10165876/
Autor:
Gang Du, Liam B. Healy, Liron David, Caitlin Walker, Pietro Fontana, Ying Dong, Pascal Devant, Robbins Puthenveetil, Scott B. Ficarro, Anirban Banerjee, Jonathan C. Kagan, Judy Lieberman, Hao Wu
Publikováno v:
bioRxiv
Gasdermin D (GSDMD) is the common effector for cytokine secretion and pyroptosis downstream of inflammasome activation by forming large transmembrane pores upon cleavage by inflammatory caspases. Here we report the surprising finding that GSDMD cleav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3637370b9e56537d4294b3a6ab12486a
https://doi.org/10.1101/2023.03.07.531538
https://doi.org/10.1101/2023.03.07.531538
Autor:
Songlin, Wang, Tata, Gopinath, Erik K, Larsen, Daniel K, Weber, Caitlin, Walker, Venkateswara Reddy, Uddigiri, Kaustubh R, Mote, Sanjaya K, Sahoo, Muthu, Periasamy, Gianluigi, Veglia
Publikováno v:
Science Advances
Description
A small peptide regulates muscle thermogenesis through interaction with the sarcoplasmic reticulum calcium ATPase.
The sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA) plays a central role in muscle contractility and nonshivering
A small peptide regulates muscle thermogenesis through interaction with the sarcoplasmic reticulum calcium ATPase.
The sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA) plays a central role in muscle contractility and nonshivering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa711e3ad37db5cbf728e08d8433673b
https://pubmed.ncbi.nlm.nih.gov/34826239
https://pubmed.ncbi.nlm.nih.gov/34826239