Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Caitlin Utt"'
Autor:
Klaus P. Hoeflich, John Hsieh, Marion Dorsch, Omar Ahmad, Clare Medendorp, Chiara Conti, Meredith Eno, Steven L. Kazmirski, Robert Meissner, Kevin Barvian, Victoria Brown, John Campbell, Timothy J. Guzi, Joseph Kim, Faith Stevison, Yoav Timsit, Tom Dineen, Dilinie Fernando, Sharon Chicklas, Scott Wardwell, Caitlin Utt, Jian Guo, Emanuele Perola, Alison J. Davis, Maria Iliou, Ayşegül Özen, Rich Woessner
Publikováno v:
Cancer Research. 81:1262-1262
BACKGROUND: Non-small cell lung cancer (NSCLC) represents 80% of lung cancers, the second leading cause of cancer deaths globally. Mutations in the kinase domain of the epidermal growth factor receptor (EGFR) are genomic drivers in a molecular sub-ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dcb45cb4fd81cd969c09f5c54697956
https://doi.org/10.1158/1538-7445.am2021-1262
https://doi.org/10.1158/1538-7445.am2021-1262
Autor:
Faris Albayya, Doug Wilson, Rich Woessner, Sun Min Lim, Zhuo Zhang, Klaus P. Hoeflich, Byoung Chul Cho, John Hsieh, John Campbell, Meredith Eno, Chae Won Park, Faith Stevison, Tom Dineen, Marion Dorsch, Caitlin Utt, Nicolas Lamontagne, Stefanie Schalm
Publikováno v:
Cancer Research. 81:1467-1467
Background: EGFR-activating mutations (L858R and ex19del) are major drivers (15-47%) of lung adenocarcinoma. EGFR TKI development has changed the treatment paradigm for EGFR-mutant (EGFR+) NSCLC. However, tumors often develop acquired resistance muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::958f36d6ca1d0005f999de30ac6e556b
https://doi.org/10.1158/1538-7445.am2021-1467
https://doi.org/10.1158/1538-7445.am2021-1467
Autor:
Tina Zimmermann, Steven Bench, Andrea Romagnani, Klaus P. Hoeflich, Carsten Wolter, Michael Sheets, Kerrie Faia, Kerry-Ann Bright, Timothy LaBranche, Marion Dorsch, Alberto Toso, Gordon Heidkamp, James R. Bischoff, Alison Ribeiro, Joshua Close, Marina Bacac, Felix Scheuplein, Nisha Perez, Caitlin Utt, Emanuele Perola, Jan Eckmann, Kristina Fetalvero, Stefan Gross, Qiongfang Cao, Debora Paduraru, Grace O. Silva, Chaoyang Ye, Marly I. Roche, Luke Green, Erin O’Hearn, Tary Traore, Weifan Weng, Jason D. Brubaker, Joseph Kim, Michael Burke, Sylvia Herter, Chandra Miduturu, Erik Gerson, Tim Guzi, Rich Woessner
Publikováno v:
Cancer Research. 81:1717-1717
Hematopoietic progenitor kinase 1 (HPK1, MAP4K1) is a serine/threonine kinase that has been demonstrated to have suppressive effects across a range of immune cells, including T cells and dendritic cells. Loss of MAP4K1 kinase activity is sufficient t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eb54e4cfffcf5824710a2a61ff8ed1c
https://doi.org/10.1158/1538-7445.am2021-1717
https://doi.org/10.1158/1538-7445.am2021-1717