Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Caitlin Unkenholz"'
Autor:
Hubert Pakula, Mohamed Omar, Ryan Carelli, Filippo Pederzoli, Giuseppe Nicolò Fanelli, Tania Pannellini, Fabio Socciarelli, Lucie Van Emmenis, Silvia Rodrigues, Caroline Fidalgo-Ribeiro, Pier Vitale Nuzzo, Nicholas J. Brady, Wikum Dinalankara, Madhavi Jere, Itzel Valencia, Christopher Saladino, Jason Stone, Caitlin Unkenholz, Richard Garner, Mohammad K. Alexanderani, Francesca Khani, Francisca Nunes de Almeida, Cory Abate-Shen, Matthew B. Greenblatt, David S. Rickman, Christopher E. Barbieri, Brian D. Robinson, Luigi Marchionni, Massimo Loda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract In the complex tumor microenvironment (TME), mesenchymal cells are key players, yet their specific roles in prostate cancer (PCa) progression remain to be fully deciphered. This study employs single-cell RNA sequencing to delineate molecular
Externí odkaz:
https://doaj.org/article/f358a6f85a6c4b2189686dbb0cfa358f
Autor:
Aleksandr Sarachakov, Arina Varlamova, Viktor Svekolkin, Ilia Galkin, Itzel Valencia, Caitlin Unkenholz, Tania Pannellini, Aida Akaeva, Sofia Smirnova, Pavel Ovcharov, Margarita Polyakova, Dmitrii Tabakov, Ekaterina Postovalova, Isha Sethi, Nara Shin, Alexander Bagaev, Tomer Itkin, Genevieve Crane, Michael Kluk, Julia Geyer, Giorgio Inghirami, Sanjay Patel
The spatial anatomy of hematopoiesis in bone marrow has been extensively studied in mice and other preclinical models, but technical challenges have precluded a commensurate exploration in humans. Institutional pathology archives contain thousands of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25da2130f6635b86c7b7b6a8402a7c96
https://doi.org/10.1101/2023.04.28.538715
https://doi.org/10.1101/2023.04.28.538715
Autor:
Hubert Pakula, Mohamed Omar, Ryan Carelli, Filippo Pederzoli, Giuseppe Nicolò Fanelli, Tania Pannellini, Lucie Van Emmenis, Silvia Rodrigues, Caroline Fidalgo-Ribeiro, Pier V. Nuzzo, Nicholas J. Brady, Madhavi Jere, Caitlin Unkenholz, Mohammad K. Alexanderani, Francesca Khani, Francisca Nunes de Almeida, Cory Abate-Shen, Matthew B Greenblatt, David S. Rickman, Christopher E. Barbieri, Brian D. Robinson, Luigi Marchionni, Massimo Loda
Publikováno v:
bioRxiv
SummaryAlterations in tumor stroma influence prostate cancer progression and metastatic potential. However, the molecular underpinnings of this stromal-epithelial crosstalk are largely unknown. Here, we compare mesenchymal cells from four genetically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd469bf64a12f21069673e08763315e
https://europepmc.org/articles/PMC10081210/
https://europepmc.org/articles/PMC10081210/
Autor:
Mohamed Omar, Hubert Pakula, Filippo Pederzoli, Giuseppe N. Fanelli, Tania Panellinni, Ryan Carelli, Silvia Rodrigues, Caroline Fidalgo-Ribeiro, Pier V. Nuzzo, Lucie V. Emmenis, Mohammad Mohammad, Madhavi Jere, Caitlin Unkenholz, David Rickman, Christopher Barbieri, Brian Robinson, Luigi Marchionni, Massimo Loda
Publikováno v:
Cancer Research. 83:1343-1343
Mesenchymal cells in the prostate cancer (PCa) tumor microenvironment (TME) contribute to the biological and clinical history of PCa. Indeed, mesenchymal cells heavily interact with cancer cells, immune cells, and the other cellular and non-cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::916b27c2540419e1bbb8c896a817ee40
https://doi.org/10.1158/1538-7445.am2023-1343
https://doi.org/10.1158/1538-7445.am2023-1343
Autor:
Hubert Pakula, Ryan Carelli, Nicolo Fanelli, Madhavi Jere, Caitlin Unkenholz, Mohamed Omar, Caroline Ribeiro- Fidalgo, Filippo Pederzoli, Cory Abate-Shen, David S. Rickman, Brian Robinson, Luigi Marchionni, Massimo Loda
Publikováno v:
Cancer Research. 82:3816-3816
Prostate cancer has a heterogeneous prognosis, and genetic alterations alone do not fully explain clinical behavior. We previously characterized the stroma of localized human prostates by Laser Capture Microdissection, and found that stroma was subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::377ba9896721b95db05381adb47b2d99
https://doi.org/10.1158/1538-7445.am2022-3816
https://doi.org/10.1158/1538-7445.am2022-3816