Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Caitlin Stashwick"'
Autor:
Amalia Brawley, Casey Moffitt, Shaina Feldman Bruce, Caitlin Stashwick Farabaugh, Edward Podczaski, Joel Sorosky
Publikováno v:
Gynecologic Oncology Reports, Vol 56, Iss , Pp 101530- (2024)
Gestational trophoblastic neoplasia (GTN) are rare diseases that are typically chemo-responsive. While the majority of patients are cured with chemotherapy alone, a small portion of cases are fatal due to chemotherapy resistance. Risk factors for tre
Externí odkaz:
https://doaj.org/article/fb29f414cdc1407894227b606deb7f36
Adoptive transfer of T cells engineered to express chimeric immunoreceptors is an effective strategy to treat hematologic cancers; however, the use of this type of therapy for solid cancers, such as ovarian cancer, remains challenging because a safe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14c3e6f15b0597745b3744a1823fa9dc
https://doi.org/10.1158/2326-6066.c.6548531.v1
https://doi.org/10.1158/2326-6066.c.6548531.v1
The expression of 18S used as a internal control (housekeeper). cDNA was constructed from total RNA isolated from 10e5 cells (cultured at 60-70% confluence). PCR performed using intron-spanning primers. Validation criteria included water blanks, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19223fd29adb63acf5a3b5bd91f864bd
https://doi.org/10.1158/2326-6066.22537712.v1
https://doi.org/10.1158/2326-6066.22537712.v1
Supplementary Figure Legend from Follicle-Stimulating Hormone Receptor as a Target in the Redirected T-cell Therapy for Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456ae2dc4d9d9e6102e0deabd8514d13
https://doi.org/10.1158/2326-6066.22537709
https://doi.org/10.1158/2326-6066.22537709
Autor:
Brawley, Amalia, Moffitt, Casey, Bruce, Shaina Feldman, Farabaugh, Caitlin Stashwick, Podczaski, Edward, Sorosky, Joel
Publikováno v:
In Gynecologic Oncology Reports December 2024 56
Autor:
Gabriela Plesa, Caitlin Stashwick, Janos L. Tanyi, Mark A. Morgan, Carl H. June, Marcela V. Maus, David L. Porter
Publikováno v:
Journal of Immunotherapy. 40:104-107
Cytokine release syndrome (CRS) is a potentially severe systemic toxicity seen after adoptive T-cell therapy and caused by T-cell activation and proliferation and is associated with elevated circulating levels of cytokines such as C-reactive protein,
Autor:
Evripidis Lanitis, Denarda Dangaj, Mathilde Poussin, Caitlin Stashwick, Daniel J. Powell, Elizabeth L. Buza, Nathalie Scholler, Jenessa B. Smith
Publikováno v:
Molecular Therapy. 24:1987-1999
B7-H4 protein is frequently overexpressed in ovarian cancer. Here, we engineered T cells with novel B7-H4-specific chimeric antigen receptors (CARs) that recognized both human and murine B7-H4 to test the hypothesis that B7-H4 CAR T cell therapy can
Publikováno v:
Immunotherapy. 8:449-460
Mesothelin is a promising target for immune-based therapy, specifically for mesothelioma and pancreatic and ovarian cancers that have high levels of mesothelin expression. Many preclinical and clinical studies that target tumors with high mesothelin
Autor:
Mark A. Morgan, Sarah Kim, Robert L. Giuntoli, A.F. Haggerty, Xiaochen Zhang, Lorraine T. Dean, Caitlin Stashwick, Kathryn H. Schmitz, David I. Shalowitz, Robert A. Burger, Lilie L. Lin, Nawar A. Latif, Emily M. Ko, Fiona Simpkins
Publikováno v:
Supportive Care in Cancer. 24:3573-3580
Racial disparities in uterine cancer-related outcomes have been reported. The goal of this study was to determine if race, pre-operative body mass index (BMI), and medical comorbidities are predictors of loss of functional independence after hysterec
Publikováno v:
Oxford Medicine
Dendritic cell vaccine therapy has emerged as an exciting new field in immunotherapy in ovarian cancer over the past two decades. This chapter reviews the biology of dendritic cells, including dendritic cell subsets, development, activation, and matu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cff485c74a9659f163bc01c98c8361a
https://doi.org/10.1093/med/9780190248208.003.0008
https://doi.org/10.1093/med/9780190248208.003.0008