Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Caitlin N. Vitro"'
Autor:
William C. Simke, Morgan E. Walker, Logan A. Calderone, Andrew T. Putz, Jon B. Patteson, Caitlin N. Vitro, Cynthia F. Zizola, Matthew R. Redinbo, Maria-Eirini Pandelia, Tyler L. Grove, Bo Li
Publikováno v:
ACS Central Science, Vol 10, Iss 8, Pp 1524-1536 (2024)
Externí odkaz:
https://doaj.org/article/1dac01033a884e3da3bf9eadc381f3d0
Publikováno v:
Bioconjugate chemistry. 32(4)
Over the past two decades, antibody drug conjugates (ADCs) and small molecule drug conjugates (SMDCs) have widely employed valine-citruline and related cathepsin-cleavable linkers due to their stability in plasma and their rapid cleavage by lysosomal