Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Caitlin M. Pavelec"'
Autor:
Scott Yeudall, Clint M. Upchurch, Philip V. Seegren, Caitlin M. Pavelec, Jan Greulich, Michael C. Lemke, Thurl E. Harris, Bimal N. Desai, Kyle L. Hoehn, Norbert Leitinger
Publikováno v:
Science Advances. 8
Acetyl-CoA carboxylase (ACC) regulates lipid synthesis; however, its role in inflammatory regulation in macrophages remains unclear. We generated mice that are deficient in both ACC isoforms in myeloid cells. ACC deficiency altered the lipidomic, tra
Publikováno v:
Circulation Research. 131
Pannexin 1 (Panx1), a ubiquitously expressed ATP release membrane channel, has been shown to play a role in inflammation and blood pressure regulation. Panx1 channel function is inhibited by spironolactone, a frontline therapy for heart failure patie
Autor:
Clint M. Upchurch, Scott Yeudall, Caitlin M. Pavelec, Dennis Merk, Jan Greulich, Mohan Manjegowda, Shyam S. Raghavan, Irina M. Bochkis, Michael M. Scott, Edward Perez-Reyes, Norbert Leitinger
Publikováno v:
Science advances. 8(28)
Oxidized phosphatidylcholines (OxPCs) are implicated in chronic tissue damage. Hyperlipidemic LDL-R-–deficient mice transgenic for an OxPC-recognizing IgM fragment (scFv-E06) are protected against nonalcoholic fatty liver disease (NAFLD). To examin
Autor:
Clint M. Upchurch, Scott Yeudall, Caitlin M. Pavelec, Mohan Manjegowda, Irina M. Bochkis, Michael Scott, Edward Perez‐Reyes, Norbert Leitinger
Publikováno v:
The FASEB Journal. 36
Publikováno v:
The FASEB Journal. 36