Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Caitlin M. Kirkwood"'
Autor:
C W Lin, Lun-Ching eChang, George C Tseng, Caitlin M Kirkwood, Etienne L Sibille, Robert A Sweet
Publikováno v:
Frontiers in Psychiatry, Vol 6 (2015)
The Visinin-like 1 (VSNL1) gene encodes Visinin-like protein 1, a peripheral biomarker for Alzheimer disease (AD). Little is known, however, about normal VSNL1 expression in brain and the biologic networks in which it participates. Frontal cortex gra
Externí odkaz:
https://doaj.org/article/134901db363b4fb4b9df2fa5b2cde30e
Autor:
Jackie Jones-Laughner, Robert A. Sweet, Nathan A. Yates, Matthew L. MacDonald, Radosveta Koldamova, M Garver, Caitlin M. Kirkwood, Milos D. Ikonomovic, Nicholas F. Fitz, Oscar L. Lopez, Tadhg A. Schempf, Ying Ding, Julia Kofler
Publikováno v:
Molecular & Cellular Proteomics. 15:2252-2262
It has been hypothesized that Alzheimer disease (AD) is primarily a disorder of the synapse. However, assessment of the synaptic proteome in AD subjects has been limited to a small number of proteins and often included subjects with end-stage patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1356213fdd083a3115cb22af397defee
https://doi.org/10.1074/mcp.m115.056580
https://doi.org/10.1074/mcp.m115.056580
Autor:
Julia Kofler, Caitlin M. Kirkwood, Patrick S. Murray, Milos D. Ikonomovic, Ronald L. Hamilton, William E. Klunk, Megan C. Gray, Kenneth N. Fish, Robert A. Sweet, Oscar L. Lopez
Publikováno v:
Journal of Alzheimer's Disease. 39:759-773
Psychosis occurs in 40-60% of Alzheimer's disease (AD) subjects, is heritable, and indicates a more rapidly progressive disease phenotype. Neuroimaging and postmortem evidence support an exaggerated prefrontal cortical synaptic deficit in AD with psy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d39869d4ad7ed2d7e1fae51da8b51e2
https://doi.org/10.3233/jad-131166
https://doi.org/10.3233/jad-131166
Autor:
Milos D. Ikonomovic, Patrick S. Murray, Peter Penzes, Julia Kofler, Megan C. Gray, Eric E. Abrahamson, Caitlin M. Kirkwood, Oscar L. Lopez, William R. Paljug, Ruth Henteleff, William E. Klunk, Robert A. Sweet, Ronald L. Hamilton
Publikováno v:
Neurobiology of Aging. 33:2807-2816
Psychosis in Alzheimer disease differentiates a subgroup with more rapid decline, is heritable, and aggregates within families, suggesting a distinct neurobiology. Evidence indicates that greater impairments of cerebral cortical synapses, particularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249ccbb7190fdd23c8e402861f26b170
https://doi.org/10.1016/j.neurobiolaging.2012.02.015
https://doi.org/10.1016/j.neurobiolaging.2012.02.015
Autor:
Mai Sun, Nathan A. Yates, Anil Varma V. Vatsavayi, Milos D. Ikonomovic, Oscar L. Lopez, Tadhg A. Schempf, Ying Ding, Julia Kofler, Caitlin M. Kirkwood, Jeremy Koppel, Robert A. Sweet, Matthew L. MacDonald
Publikováno v:
Journal of neuropathology and experimental neurology. 75(2)
Recent studies have implicated the neuronal calcium-sensing protein visinin-like 1 protein (Vilip-1) as a peripheral biomarker in Alzheimer disease (AD), but little is known about expression of Vilip-1 in the brains of patients with AD. We used targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13870e7c9764d147e897a5d6545f231b
https://pubmed.ncbi.nlm.nih.gov/26769253
https://pubmed.ncbi.nlm.nih.gov/26769253
Autor:
C W Lin, Lun-Ching eChang, George C Tseng, Caitlin M Kirkwood, Etienne L Sibille, Robert A Sweet
Publikováno v:
Frontiers in Psychiatry
Frontiers in Psychiatry, Vol 6 (2015)
Frontiers in Psychiatry, Vol 6 (2015)
The visinin-like 1 (VSNL1) gene encodes visinin-like protein 1, a peripheral biomarker for Alzheimer disease (AD). Little is known, however, about normal VSNL1 expression in brain and the biologic networks in which it participates. Frontal cortex gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22babe0d0442e2faa7d85c9a870d1118
https://pubmed.ncbi.nlm.nih.gov/25806004
https://pubmed.ncbi.nlm.nih.gov/25806004
Autor:
Robert A. Sweet, Jennifer Ciuchta, William E. Klunk, Patrick S. Murray, Milos D. Ikonomovic, Caitlin M. Kirkwood, Eric E. Abrahamson, Kenneth N. Fish
Publikováno v:
Journal of neuropathology and experimental neurology. 72(8)
Dendritic spines are the site of the majority of excitatory synapses, the loss of which correlates with cognitive impairment in patients with Alzheimer disease. Substantial evidence indicates that amyloid-β (Aβ) peptide, either insoluble fibrillar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5449aec142a7350ec0d0f7f4e525e8
https://pubmed.ncbi.nlm.nih.gov/23860033
https://pubmed.ncbi.nlm.nih.gov/23860033
Autor:
Milos D. Ikonomovic, Patrick S. Murray, Caitlin M. Kirkwood, Robert A. Sweet, Kenneth N. Fish
Publikováno v:
The American Journal of Geriatric Psychiatry. 21:S80-S81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::876f2a89713027d9efc5d675247a77a1
https://doi.org/10.1016/j.jagp.2012.12.105
https://doi.org/10.1016/j.jagp.2012.12.105