Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Caitlin M. Davis"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Studying protein kinetics and stability in living organisms is challenging and most studies are performed in cell culture. Here the authors combine meganuclease-mediated transformation and fluorescence-detected temperature-jump microscopy to quantify
Externí odkaz:
https://doaj.org/article/ab1a9da76c7a4019856d44a01cb0d86b
Publikováno v:
Avian Conservation and Ecology, Vol 12, Iss 2, p 5 (2017)
Nest boxes are posted to provide breeding sites for cavity-nesting birds but less is known about their function in the nonbreeding season, when nest boxes may become important roost sites. In winter months, we surveyed 79 nest boxes before dawn for r
Externí odkaz:
https://doaj.org/article/aa7408cdcaf047a78b158d9e5465f7d9
Publikováno v:
The Journal of Physical Chemistry B. 127:2918-2926
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b2acd2f7d3e03fcf6b3d6276393d3b0
https://doi.org/10.1021/acs.jpcb.2c08812
https://doi.org/10.1021/acs.jpcb.2c08812
Publikováno v:
Nucleic Acids Research. 50:8193-8206
The RNA recognition motif (RRM) occurs widely in RNA-binding proteins, but does not always by itself support full binding. For example, it is known that binding of SL1 RNA to the protein U1-70K in the U1 spliceosomal particle is reduced when a region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ff35f1c2a779d2416582c1cd5f71fc
https://doi.org/10.1093/nar/gkac599
https://doi.org/10.1093/nar/gkac599
Autor:
Hyejin Yoo, Caitlin M. Davis
Publikováno v:
ChemBioChem. 23
To discover the cytomimetic that accounts for cytoplasmic crowding and sticking on RNA stability, we conducted a two-dimensional scan of mixtures of artificial crowding and sticking agents, PEG10k and M-PER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d1f807acecf49854bfad5c64c570d2
https://doi.org/10.1002/cbic.202200406
https://doi.org/10.1002/cbic.202200406
Autor:
Martin Gruebele, Caitlin M. Davis
Publikováno v:
The Journal of Physical Chemistry B. 125:3815-3823
While extensive studies have been carried out to determine protein-RNA binding affinities, mechanisms, and dynamics in vitro, such studies do not take into consideration the effect of the many weak nonspecific interactions in a cell filled with poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1498c9fc6067133e469ccf8123b9733e
https://doi.org/10.1021/acs.jpcb.1c00950
https://doi.org/10.1021/acs.jpcb.1c00950
Autor:
Caitlin M. Davis, Martin Gruebele
Publikováno v:
Biochemistry. 59:2650-2659
The dynamic cytoskeletal network of microtubules and actin filaments can be disassembled by drugs. Cytoskeletal drugs work by perturbing the monomer-polymer equilibrium, thus changing the size and number of macromolecular crowders inside cells. Chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef36d84a63e3cd93386bde50b5a34858
https://doi.org/10.1021/acs.biochem.0c00299
https://doi.org/10.1021/acs.biochem.0c00299
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Nature Communications
Nature Communications
As an integral part of modern cell biology, fluorescence microscopy enables quantification of the stability and dynamics of fluorescence-labeled biomolecules inside cultured cells. However, obtaining time-resolved data from individual cells within a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae24e9837e421af8b373f46544b3874
http://link.springer.com/article/10.1038/s41467-019-09088-y
http://link.springer.com/article/10.1038/s41467-019-09088-y
Autor:
Caitlin M. Davis, Martin Gruebele
Publikováno v:
ChemPhysChem. 19:2290-2294
Although biomolecules evolved to function in the cell, most biochemical assays are carried out in vitro. In-cell studies highlight how steric and non-steric interactions modulate protein folding and interactions. VlsE and PGK present two extremes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147800eca8d402ed5dd5d11365fa9068
https://doi.org/10.1002/cphc.201800534
https://doi.org/10.1002/cphc.201800534
Autor:
Caitlin M. Davis, Martin Gruebele
Publikováno v:
Biochemistry. 57:1929-1938
Qualitative imaging of biomolecular localization and distribution inside cells has revolutionized cell biology. Most of these powerful techniques require modifications to the target biomolecule. Over the past 10 years, these techniques have been exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85648785117e911d61a0844ba457c582
https://doi.org/10.1021/acs.biochem.8b00141
https://doi.org/10.1021/acs.biochem.8b00141