Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Caitlin K. Thirnbeck"'
Autor:
Xiuqiong Zhou, YuJaung Kim, Se Hee Kim, George B. Richerson, Eduardo Bravo, Brian K. Gehlbach, Douglas R. Nordli, Linda Laux, Caitlin K. Thirnbeck, Lori A. Smith-Mellecker
Publikováno v:
Journal of Clinical Investigation. 128:1141-1153
Dravet syndrome (DS) is a severe childhood-onset epilepsy commonly due to mutations of the sodium channel gene SCN1A. Patients with DS have a high risk of sudden unexplained death in epilepsy (SUDEP), widely believed to be due to cardiac mechanisms.
Autor:
Amanda E. Kozlowski, Matthew J. Potthoff, Maya E. Kotas, Kirstie L. Leslie, Matthew P. Gillum, Kathleen R. Markan, Caitlin K. Thirnbeck, George B. Richerson, Michelle C. Gorecki, Jacob McGlashon
Publikováno v:
Cell metabolism. 21(5)
SummaryThermogenic brown and beige adipocytes convert chemical energy to heat by metabolizing glucose and lipids. Serotonin (5-HT) neurons in the CNS are essential for thermoregulation and accordingly may control metabolic activity of thermogenic fat