Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Caitlin K. Cavanaugh"'
Autor:
Colin M. Tice, Caitlin K. Cavanaugh, Robert Eugene Hormann, Jessica A. Saggers, Christine S. Thompson, Jennifer L. Friz
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:1883-1886
Fifteen new α-acylaminoketones were prepared by four different routes in an initial effort to optimize the potency of these compounds as ecdysone agonists. The compounds were assayed in mammalian cells expressing the ecdysone receptors from Bombyx m
Autor:
Howard Smith, Jennifer L. Friz, Christine S. Thompson, Colin M. Tice, Jessica A. Saggers, Javier Garcia, Enrique Luis Michelotti, Caitlin K. Cavanaugh
Publikováno v:
ChemInform. 34
A library of 35 cis-1-benzoyl-2-methyl-4-(phenylamino)-1,2,3,4-tetrahydroquinolines was prepared. The compounds bore various substitutuents on the benzoyl ring, at the 4-position of the phenylamino ring and at the 6-position of the tetrahydroquinolin
Autor:
Christine S. Thompson, Javier Garcia, Fernando Albericio, Enrique Luis Michelotti, Ernesto Nicolás, Robert Eugene Hormann, Caitlin K. Cavanaugh, Colin M. Tice, Jennifer L. Friz
Publikováno v:
ChemInform. 34
A lead discovery library and a follow-up focused library of α-acylaminoketones were designed based on known dibenzoylhydrazine ecdysone agonists, including GS ™ –E. The compounds were assayed in mammalian cells expressing the ecdysone receptor f