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Identification of Histidine 303 as the Catalytic Base of Lysyl Oxidase via Site-Directed Mutagenesis
Autor:
Caitlin Ghilarducci, Rachel N. Oldfield, Jeanette Limones, Kathryn A. Johnston, Karlo M. Lopez
Publikováno v:
The protein journal. 37(1)
Lysyl oxidase (LOX) is a copper-dependent amine oxidase enzyme that catalyzes the formation of crosslinkages of collagen and elastin in connective tissues by oxidative deamination of lysine. Using site-directed mutagenesis, Histidine 303 has been sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829063d80a1d5ac78fec08dca27f0c26
https://pubmed.ncbi.nlm.nih.gov/29127553
https://pubmed.ncbi.nlm.nih.gov/29127553
