Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Caitlin E. Randolph"'
Autor:
Armen G. Beck, Matthew Muhoberac, Caitlin E. Randolph, Connor H. Beveridge, Prageeth R. Wijewardhane, Hilkka I. Kenttämaa, Gaurav Chopra
Publikováno v:
ACS Measurement Science Au, Vol 4, Iss 3, Pp 233-246 (2024)
Externí odkaz:
https://doaj.org/article/5caf1314292048a29005f7ed9a3a51da
Autor:
Caitlin E. Randolph, Connor H. Beveridge, Sanjay Iyer, Stephen J. Blanksby, Scott A. McLuckey, Gaurav Chopra
Publikováno v:
J Am Soc Mass Spectrom
While various mass spectrometric approaches have been applied to lipid analysis, unraveling the extensive structural diversity of lipids remains a significant challenge. Notably, these approaches often fail to differentiate between isomeric lipids -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9400f0c33407af279274118a7a129900
https://pubmed.ncbi.nlm.nih.gov/36218280
https://pubmed.ncbi.nlm.nih.gov/36218280
Publikováno v:
Anal Chem
Shotgun lipidomics has recently gained popularity for lipid analysis. Conventionally, shotgun analysis of glycerophospholipids via direct electrospray ionization tandem mass spectrometry (ESI-MS/MS) provides glycerophospholipid (GPL) class (i.e., hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3270d46ef2488695dfd2f5ed11c9f7ef
https://doi.org/10.1021/acs.analchem.9b04376
https://doi.org/10.1021/acs.analchem.9b04376
Publikováno v:
Anal Bioanal Chem
Shotgun lipid analysis based on electrospray ionization-tandem mass spectrometry (ESI-MS/MS) is increasingly used in lipidomic studies. One challenge for the shotgun approach is the discrimination of lipid isomers and isobars. Gas-phase charge invers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5830af7eed67ea4b62665885d95d574d
https://doi.org/10.1007/s00216-018-1537-1
https://doi.org/10.1007/s00216-018-1537-1
Publikováno v:
J Am Soc Mass Spectrom
Cardiolipins (CLs) are comprised of two phosphatic acid moieties bound to a central glycerol backbone and are substituted with four acyl chains. Consequently, a vast number of distinct CL structures are possible in different biological contexts, repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa199b6fe30c907dfdef50912221d7a
https://pubmed.ncbi.nlm.nih.gov/33370110
https://pubmed.ncbi.nlm.nih.gov/33370110
Publikováno v:
Anal Chem
Cardiolipin (CL) analysis demands high specificity, due to the extensive diversity of CL structures, and high sensitivity, due to their low relative abundance within the lipidome. While electrospray ionization mass spectrometry (ESI-MS) is the most w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ecfb50ac95d3935951169e31b8e00c
https://pubmed.ncbi.nlm.nih.gov/32639138
https://pubmed.ncbi.nlm.nih.gov/32639138
Publikováno v:
Anal Chim Acta
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a recently discovered class of endogenous bioactive lipids with anti-diabetic and anti-inflammatory effects. Identification of FAHFAs is challenging due to both the relatively low abundan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b038b44f29c5463fdf6e68ad91c62f
https://pubmed.ncbi.nlm.nih.gov/32891388
https://pubmed.ncbi.nlm.nih.gov/32891388
Publikováno v:
J Am Soc Mass Spectrom
Ether lipids represent a unique subclass of glycerophospholipid (GPL) that possesses a 1-O-alkyl (i.e., plasmanyl subclass) or a 1-O-alk-1'-enyl (i.e., plasmenyl subclass) group linked at the sn-1 position of the glycerol backbone. As changes in ethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a77fa8636ebf4020ceada5ff94821f
https://pubmed.ncbi.nlm.nih.gov/32251588
https://pubmed.ncbi.nlm.nih.gov/32251588
Autor:
Stella K. Betancourt, Caitlin E Randolph, David J. Foreman, Scott A. McLuckey, Stephen J. Blanksby
Publikováno v:
Analytical Chemistry. 90:12861-12869
Fatty acids (FA) play vital biological roles as energy sources, signaling molecules and key building blocks of complex lipids in cell membranes. Modifications to FA structure and composition are associated with the onset and progression of a number o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d55b6ba7bdff032c2c6a4266d191e87
https://doi.org/10.1021/acs.analchem.8b03441
https://doi.org/10.1021/acs.analchem.8b03441
Publikováno v:
Anal Chem
Representing the most fundamental lipid class, fatty acids (FA) play vital biological roles serving as energy sources, cellular signaling molecules, and key architectural components of complex lipids. Direct infusion electrospray ionization spectrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65315aab101e678f5c9720361354bf14
https://europepmc.org/articles/PMC6882335/
https://europepmc.org/articles/PMC6882335/
