Seeing stars: Development and function of retinal astrocytes

Autor: Jeremy N. Kay, Caitlin E. Paisley

Publikováno v: Dev Biol

Throughout the central nervous system, astrocytes adopt precisely ordered spatial arrangements of their somata and arbors, which facilitate their many important functions. Astrocyte pattern formation is particularly important in the retina, where ast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1999d473eddd2b08bc9dee0d284f2e
https://doi.org/10.1016/j.ydbio.2021.07.007

Large-scale death of retinal astrocytes during normal development is non-apoptotic and implemented by microglia

Autor: Monica A. Lee, Robin M. Perelli, Jeremy N. Kay, Benjamin E. Reese, Emily G. O’Koren, Federica S. Brecha, Caroline R. Ackley, Caitlin E. Paisley, Daniel R. Saban, Jingjing Wang, Vanessa M. Puñal

Publikováno v: PLoS biology, vol 17, iss 10
PLoS Biology
PLoS Biology, Vol 17, Iss 10, p e3000492 (2019)

Naturally occurring cell death is a fundamental developmental mechanism for regulating cell numbers and sculpting developing organs. This is particularly true in the nervous system, where large numbers of neurons and oligodendrocytes are eliminated v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135ffc987729a19b8a481b41ced4c6c4
https://escholarship.org/uc/item/595857hg

Novel role of the nociceptin system as a regulator of glutamate transporter expression in developing astrocytes

Autor: Caitlin E. Paisley, Logan C. Meyer, Tomasz Kordula, Kabirullah Lutfy, Carmen Sato-Bigbee, Hope Richard, John W. Bigbee, Esraa Mohamed

Publikováno v: Glia, vol 65, iss 12
Meyer, LC; Paisley, CE; Mohamed, E; Bigbee, JW; Kordula, T; Richard, H; et al.(2017). Novel role of the nociceptin system as a regulator of glutamate transporter expression in developing astrocytes.. Glia, 65(12), 2003-2023. doi: 10.1002/glia.23210. UC Office of the President: Tobacco-Related Disease Research Program. Retrieved from: http://www.escholarship.org/uc/item/2cr1c0zq

Our previous results showed that oligodendrocyte development is regulated by both nociceptin and its G-protein coupled receptor, the nociceptin/orphanin FQ receptor (NOR). The present in vitro and in vivo findings show that nociceptin plays a crucial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2486d1452099030a6f73939241e4e155
https://escholarship.org/uc/item/2cr1c0zq