Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Caitlin E. Moyer"'
Autor:
Rochelle L. Coulson, Valentina Frattini, Caitlin E. Moyer, Jennifer Hodges, Peter Walter, Philippe Mourrain, Yi Zuo, Gordon X. Wang
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109259- (2024)
Summary: Fragile X syndrome (FXS) is caused by the loss of fragile X messenger ribonucleoprotein (FMRP), a translational regulator that binds the transcripts of proteins involved in synaptic function and plasticity. Dysregulated protein synthesis is
Externí odkaz:
https://doaj.org/article/eda84da98ffe4e3aac6c377083d3d94c
Publikováno v:
PLoS Medicine, Vol 18, Iss 9, p e1003802 (2021)
Externí odkaz:
https://doaj.org/article/02d6f384a6eb49499b5c7f1c11ee7133
Autor:
Caitlin E Moyer
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 18, Iss 9, p e1003800 (2021)
PLoS Medicine, Vol 18, Iss 9, p e1003800 (2021)
Caitlin Moyer discusses PLOS Medicine's Special Issue on Global Child and Adolescent Health.
Autor:
Caitlin E. Moyer, Emma M. Hiolski, Kathi A. Lefebvre, David J. Marcinek, Yi Zuo, Donald R. Smith
Domoic acid (DA) is a neurotoxin produced during harmful algal blooms that accumulates in marine organisms that serve as food resources for humans. While acute DA neurotoxicity can cause seizures and hippocampal lesions, less is known regarding how c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca5610abce498deb20cfe3bad06fab4
https://europepmc.org/articles/PMC6237202/
https://europepmc.org/articles/PMC6237202/
Autor:
Caitlin E. Moyer, Yi Zuo
Publikováno v:
Current opinion in neurobiology. 53
Dendritic spines are the postsynaptic sites of most excitatory synapses in the cerebral cortex. Their morphology and density change throughout life, reflecting the maturation and reorganization of excitatory circuits. The development of in vivo two-p
Autor:
Peter P. Zandi, Benjamin N.R. Cheyette, Pierre-Marie Martin, Kimberly A. Mulligan, Shaun Purcell, James B. Potash, Caitlin E. Moyer, Robert E. Stanley, Adam P. Ross, Stephen Sanders, Andiara E. Freitas, Audrey C. Brumback, S. Dominguez, Saul Kivimäe, W. R. McCombie, Mehdi Pirooznia, K. S. Stapornwongkul, Yi Zuo, Vikaas S. Sohal, Jillian Iafrati
Publikováno v:
Molecular psychiatry, vol 23, iss 2
Molecular psychiatry
Molecular psychiatry
Mice lacking DIX domain containing-1 (DIXDC1), an intracellular Wnt/β-catenin signal pathway protein, have abnormal measures of anxiety, depression and social behavior. Pyramidal neurons in these animals' brains have reduced dendritic spines and glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f57a2f67bc852c968f0e7dc37fb84f3
https://escholarship.org/uc/item/0pk9f0px
https://escholarship.org/uc/item/0pk9f0px
Publikováno v:
Neuroscience Letters. 601:46-53
Schizophrenia is a chronic illness affecting approximately 0.5–1% of the world’s population. The etiology of schizophrenia is complex, including multiple genes, and contributing environmental effects that adversely impact neurodevelopment. Nevert
Autor:
Caitlin E. Moyer, Robert A. Sweet, Susan L. Erickson, Edda Thiels, Peter Penzes, Kenneth N. Fish
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991). 26(5)
Cortical excitatory and inhibitory synapses are disrupted in schizophrenia, the symptoms of which often emerge during adolescence, when cortical excitatory synapses undergo pruning. In auditory cortex, a brain region implicated in schizophrenia, litt
Autor:
Benjamin N.R. Cheyette, Stephen Sanders, Audrey C. Brumback, Caitlin E. Moyer, Robert E. Stanley, Shaun Purcell, Andiara E. Freitas, Vikaas S. Sohal, Jillian Iafrati, Adam P. Ross, Mehdi Pirooznia, Yi Zuo, Pierre-Marie Martin, James B. Potash, Peter P. Zandi, W. Richard McCombie
Publikováno v:
Biological Psychiatry. 81:S286
Background A major direct target of lithium is the metalloenzyme GSK3, the central kinase in the Wnt/β-catenin pathway broadly involved in neural development. Methods We have investigated neurodevelopmental and behavioral functions of DIXDC1, which
Autor:
Matthew L. MacDonald, David A. Lewis, James V. Dibitetto, Kenneth N. Fish, Karl Anton Dorph-Petersen, Peter Penzes, Micah A. Shelton, Caitlin E. Moyer, Jason T. Newman, Hong Gu, Robert A. Sweet, Allan R. Sampson
Publikováno v:
Shelton, M A, Newman, J T, Gu, H, Sampson, A R, Fish, K N, MacDonald, M L, Moyer, C E, DiBitetto, J V, Dorph-Petersen, K-A, Penzes, P, Lewis, D A & Sweet, R A 2015, ' Loss of Microtubule-Associated Protein 2 Immunoreactivity Linked to Dendritic Spine Loss in Schizophrenia ', Biological Psychiatry, vol. 78, pp. 374-385 . https://doi.org/10.1016/j.biopsych.2014.12.029
BACKGROUND: Microtubule-associated protein 2 (MAP2) is a neuronal protein that plays a role in maintaining dendritic structure through its interaction with microtubules. In schizophrenia (Sz), numerous studies have revealed that the typically robust