Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Caitlin Davies"'
Autor:
Eleanor K. Pickett, Abigail G. Herrmann, Jamie McQueen, Kimberly Abt, Owen Dando, Jane Tulloch, Pooja Jain, Sophie Dunnett, Sadaf Sohrabi, Maria P. Fjeldstad, Will Calkin, Leo Murison, Rosemary J. Jackson, Makis Tzioras, Anna Stevenson, Marie d’Orange, Monique Hooley, Caitlin Davies, Marti Colom-Cadena, Alejandro Anton-Fernandez, Declan King, Iris Oren, Jamie Rose, Chris-Anne McKenzie, Elizabeth Allison, Colin Smith, Oliver Hardt, Christopher M. Henstridge, Giles E. Hardingham, Tara L. Spires-Jones
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3592-3604.e5 (2019)
Summary: A key knowledge gap blocking development of effective therapeutics for Alzheimer’s disease (AD) is the lack of understanding of how amyloid beta (Aβ) peptide and pathological forms of the tau protein cooperate in causing disease phenotype
Externí odkaz:
https://doaj.org/article/5c607706c23f4f7d92a682e925ca0372
Autor:
Livia Salvati Manni, Caitlin Davies, Kathleen Wood, Salvatore Assenza, Rob Atkin, Gregory G. Warr
Publikováno v:
Journal of Colloid and Interface Science. 643:276-281
Autor:
Martí Colom-Cadena, Caitlin Davies, Sònia Sirisi, Ji-Eun Lee, Elizabeth Simzer, Makis Tzioras, Marta Querol-Vilaseca, Érika Sánchez-Aced, Ya Yin Chang, Kris Holt, Robert McGeachan, Jamie Rose, Jane Tulloch, Lewis Wilkins, Colin Smith, Teodora Andrian, Olivia Belbin, Sílvia Pujals, Mathew H. Horrocks, Alberto Lleó, Tara Spires-Jones
Publikováno v:
Colom Cadena, M, Davies, C, Sirisi, S, Lee, J-E, Simzer, E M, Tzioras, M, Querol-Vilaseca, M, Sanchez-Aced, E, Chang, Y Y, Holt, K, McGeachan, R I, Rose, J, Tulloch, J, Wilkins, L, Smith, C, Andrian, T, Belbin, O, Pujals, S, Horrocks, M H, Lleó, A & Spires-Jones, T L 2023, ' Synaptic oligomeric tau in Alzheimer’s disease – a potential culprit in the spread of tau pathology through the brain ', Neuron . https://doi.org/10.1016/j.neuron.2023.04.020
SummaryIn Alzheimer’s disease (AD), fibrillar tau pathology accumulates and spreads through the brain and synapses are lost. Evidence from mouse models indicates that tau spreads trans-synaptically from pre- to postsynapses and that oligomeric tau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83350f6031960b19e74616d7b3c9cb2f
https://www.pure.ed.ac.uk/ws/files/349206122/mmc2.pdf
https://www.pure.ed.ac.uk/ws/files/349206122/mmc2.pdf
Publikováno v:
Trends in Chemistry. 4:318-330
Autor:
Caroline A. W. Dickson, Caitlin Davies, Brendan McCormack, Liz Westcott, Joy Merrell, Sonja Mcilfatrick, Jan Dewing
Publikováno v:
Journal of nursing managementREFERENCES. 30(8)
We aim to explore healthful leadership practices in nursing and midwifery evident within the COVID-19 pandemic in the United Kingdom, the contextual facilitators, barriers and outcomes.Globally, the health and care sectors are under pressure and desp
Autor:
Caitlin Davies, Lara Dötsch, Maria Gessica Ciulla, Elisabeth Hennes, Kei Yoshida, Raphael Gasper, Rebecca Scheel, Sonja Sievers, Carsten Strohmann, Kamal Kumar, Slava Ziegler, Herbert Waldmann
Publikováno v:
Angewandte Chemie (International ed. in English). 61(40)
Natural product (NP)-inspired design principles provide invaluable guidance for bioactive compound discovery. Pseudo-natural products (PNPs) are de novo combinations of NP fragments to target biologically relevant chemical space not covered by NPs. W
Autor:
Caitlin Davies
Publikováno v:
New Zealand Economic Papers. 56:219-234
I consider whether imperfect macroprudential policy can be ‘improved’ upon by a monetary policy of leaning against the wind. Imperfect macroprudential policy is captured by instrument uncertainty, ...
Publikováno v:
European Journal of Organic Chemistry. 2020:6512-6524
Cysteine string protein alpha accumulates with early pre-synaptic dysfunction in Alzheimer’s disease
Autor:
Huzefa Rupawala, Keshvi Shah, Caitlin Davies, Jamie Rose, Marti Colom-Cadena, Xianhui Peng, Lucy Granat, Manal Aljuhani, Keiko Mizuno, Claire Troakes, Beatriz Gomez Perez-Nievas, Alan Morgan, Po-Wah So, Tibor Hortobagyi, Tara L Spires-Jones, Wendy Noble, Karl Peter Giese
Publikováno v:
Rupawala, H, Shah, K, Davies, C, Rose, J, Colom-Cadena, M, Peng, X, Granat, L, Aljuhani, M, Mizuno, K, Troakes, C, Perez-Nievas, B G, Morgan, A, So, P-W, Hortobagyi, T, Spires-Jones, T L, Noble, W & Giese, K P 2022, ' Cysteine string protein alpha accumulates with early pre-synaptic dysfunction in Alzheimer's disease ', Brain Communications, vol. 4, no. 4, fcac192, pp. fcac192 . https://doi.org/10.1093/braincomms/fcac192
Brain communications
Brain communications
In Alzheimer’s disease, synapse loss causes memory and cognitive impairment. However, the mechanisms underlying synaptic degeneration in Alzheimer’s disease are not well understood. In the hippocampus, alterations in the level of cysteine string
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c969cb1de3bf9724f960761798cc4c