Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Caitlin Burzynski"'
Autor:
Catherine A. Schweppe, Jean Lud Cadet, Eliot L. Gardner, Subramaniam Jayanthi, Amy Hauck Newman, Thomas M. Keck, Bruce Ladenheim, Zheng-Xiong Xi, Henriette van Praag, Caitlin Burzynski
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Abuse of the psychostimulant methamphetamine (METH) can cause long-lasting damage to brain monoaminergic systems and is associated with profound mental health problems for users, including lasting cognitive impairments. Animal models of ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e39e005160eda163e889507084ad60
https://doi.org/10.1007/s00213-020-05513-z
https://doi.org/10.1007/s00213-020-05513-z
Autor:
Caitlin Burzynski, Rana Rais, Comfort A. Boateng, Amy Hauck Newman, Oluyomi M. Bakare, Thomas M. Keck, Elie Pommier, Jonathan A. Javitch, Zheng-Xiong Xi, Jia Zhan, Barbara S. Slusher, Prashant Donthamsetti, Ashwini K. Banala
Publikováno v:
Journal of Medicinal Chemistry
The dopamine D3 receptor (D3R) is a promising target for the development of pharmacotherapeutics to treat substance use disorders. Several D3R-selective antagonists are effective in animal models of drug abuse, especially in models of relapse. Nevert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dbb10e40377b8965f9aed3b6766a60
https://doi.org/10.1021/acs.jmedchem.5b00776
https://doi.org/10.1021/acs.jmedchem.5b00776
Autor:
Ashwini K. Banala, Martin H. Moore, Rana Rais, Barbara S. Slusher, Rachel D. Slack, Amy Hauck Newman, Caitlin Burzynski, Jeffrey R. Deschamps, Oluyomi M. Okunola-Bakare, Thomas M. Keck, Alessandro Bonifazi
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:4000-4012
The dopamine D3 receptor (D3R) is a target of pharmacotherapeutic interest in a variety of neurological disorders including schizophrenia, Parkinson's disease, restless leg syndrome, and drug addiction. A common molecular template used in the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81a04d310bf91ce40921b649007718c
https://doi.org/10.1016/j.bmc.2015.01.017
https://doi.org/10.1016/j.bmc.2015.01.017
Autor:
Hideaki Yano, Alessandro Bonifazi, Claus J. Loland, Guo Hua Bi, Caitlin Burzynski, Oluyomi M. Bakare, Jianjing Cao, Amy Hauck Newman, Rana Rais, Rachel D. Slack, Barbara S. Slusher, Theresa A. Kopajtic, Yi He, Michael P. Ellenberger, Zheng-Xiong Xi
Publikováno v:
Journal of medicinal chemistry. 59(23)
The development of pharmacotherapeutic treatments of psychostimulant abuse has remained a challenge, despite significant efforts made toward relevant mechanistic targets, such as the dopamine transporter (DAT). The atypical DAT inhibitors have receiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839a67a1bfaf9c3e42fea87d01ab1dec
https://pubmed.ncbi.nlm.nih.gov/27933960
https://pubmed.ncbi.nlm.nih.gov/27933960
Autor:
Prashant Donthamsetti, Caitlin Burzynski, Mu Fa Zou, Jonathan A. Javitch, Alessandro Bonifazi, Vivek Kumar, Catherine Schweppe, Mayako Michino, R. Benjamin Free, Aaron Janowsky, Lei Shi, David R. Sibley, Amy Hauck Newman, Thomas M. Keck
Publikováno v:
Journal of Medicinal Chemistry
Novel 1-, 5-, and 8-substituted analogues of sumanirole (1), a dopamine D2/D3 receptor (D2R/D3R) agonist, were synthesized. Binding affinities at both D2R and D3R were higher when determined in competition with the agonist radioligand [(3)H]7-hydroxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa402968be5d1f258ed88cbd99e0065
https://pubmed.ncbi.nlm.nih.gov/27035329
https://pubmed.ncbi.nlm.nih.gov/27035329
Autor:
Caitlin Burzynski, Sarah C. Zimmermann, Rana Rais, Barbara S. Slusher, Takashi Tsukamoto, Jesse Alt
Representative d-amino acid oxidase (DAAO) inhibitors were subjected to in vitro liver microsomal stability tests in the absence or presence of uridine diphosphate glucuronic acid (UDPGA). While carboxylate-based DAAO inhibitors displayed little gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04120a8dc392f7e09066f34b47fb663
https://europepmc.org/articles/PMC4233358/
https://europepmc.org/articles/PMC4233358/
The dopamine D3 receptor is a target of pharmacotherapeutic interest in a variety of neurological disorders including schizophrenia, restless leg syndrome, and drug addiction. The high protein sequence homology between the D3 and D2 receptors has pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06e5474e400f7f6c54817119e8e3f04e
https://doi.org/10.1016/b978-0-12-420118-7.00007-x
https://doi.org/10.1016/b978-0-12-420118-7.00007-x
Autor:
ComfortA. Boateng, Oluyomi M. Bakare, Jia Zhan, Ashwini K. Banala, Caitlin Burzynski, Elie Pommier, ThomasM. Keck, Prashant Donthamsetti, Jonathan A. Javitch, Rana Rais, Barbara S. Slusher, Zheng-Xiong Xi, Amy Hauck Newman
Publikováno v:
Journal of Medicinal Chemistry; Aug2015, Vol. 58 Issue 15, p6195-6213, 19p