Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Caitlin B Conboy"'
Autor:
Roberto Alva‐Ruiz, Ryan D. Watkins, Jennifer L. Tomlinson, Jennifer A. Yonkus, Amro M. Abdelrahman, Caitlin B. Conboy, Erik Jessen, Nathan W. Werneburg, Hendrien Kuipers, Jack W. Sample, Gregory J. Gores, Sumera I. Ilyas, Mark J. Truty, Rory L. Smoot
Publikováno v:
FEBS Open Bio, Vol 14, Iss 11, Pp 1873-1887 (2024)
Cholangiocarcinoma (CCA) is a highly aggressive form of liver cancer and is an increasing cause of cancer‐related death worldwide. Despite its increasing incidence globally and alarming mortality, treatment options for CCA have largely remained unc
Externí odkaz:
https://doaj.org/article/c06dce51bdf6443f86bb9d8ffcc1a4dc
Autor:
Branden S Moriarity, Eric P Rahrmann, Dominic A Beckmann, Caitlin B Conboy, Adrienne L Watson, Daniel F Carlson, Erik R Olson, Kendra A Hyland, Scott C Fahrenkrug, R Scott McIvor, David A Largaespada
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96114 (2014)
The advent of Transcription Activator-Like Effector Nucleases (TALENs), and similar technologies such as CRISPR, provide a straightforward and cost effective option for targeted gene knockout (KO). Yet, there is still a need for methods that allow fo
Externí odkaz:
https://doaj.org/article/a67c56a202d14176b28d0ed4ffb24785
Autor:
Caitlin B. Conboy, Germán L. Vélez‐Reyes, Barbara R. Tschida, Hsiangyu Hu, Gabriel Kaufmann, Nicholas Koes, Bryant Keller, Clara Alsinet, Helena Cornellà, Roser Pinyol, Juan E. Abrahante, Nuri A. Temiz, Michael A. Linden, Khalid Amin, Timothy P. Kuka, Vincent W. Keng, Josep M. Llovet, Timothy K. Starr, David A. Largaespada
Publikováno v:
Hepatology Communications, Vol 3, Iss 11, Pp 1496-1509 (2019)
Each year, more than 25,000 people succumb to liver cancer in the United States, and this neoplasm represents the second cause of cancer‐related death globally. R‐spondins (RSPOs) are secreted regulators of Wnt signaling that function in developm
Externí odkaz:
https://doaj.org/article/0eab1ccaa58a47a08d90c0ba26613dba
Publikováno v:
JHEP Reports, Vol 1, Iss 4, Pp 297-311 (2019)
Summary: Cholangiocarcinoma (CCA) represents a heterogeneous group of epithelial tumours that are classified according to anatomical location as intrahepatic (iCCA), perihilar (pCCA), or distal (dCCA). Although surgical resection and liver transplant
Externí odkaz:
https://doaj.org/article/3019c687195b404d9ca7abb6d4f621df
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Figure 4 - PDF file 111K, Reduction of Wnt signaling by β-catenin knockdown or GSK3B overexpression reduces tumor growth in xenograft models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bce1b4500ae8aa47f763841e42aa42b
https://doi.org/10.1158/2159-8290.22530711
https://doi.org/10.1158/2159-8290.22530711
Autor:
Rory L. Smoot, Sumera Rizvi, Chen Wang, Daniel R. O'Brien, Ayano Kabashima, Caitlin B. Conboy, Nathan W. Werneburg, EeeLN H. Buckarma
SHP2 inhibition by NSC also shifts YAP from a cytoplasmic to nuclear compartment in a non-CCA cell line.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0305dd1a83b466a4ae36179001b321d
https://doi.org/10.1158/1541-7786.22514286
https://doi.org/10.1158/1541-7786.22514286
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Table 2 - PDF 69K, QPCR primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f54fa0e01e8181316838630811d03c
https://doi.org/10.1158/2159-8290.22530705
https://doi.org/10.1158/2159-8290.22530705
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Figure 2 - PDF file 109K, Overexpression of activated β-catenin and knockdown of AXIN1 or GSK3B results in increased Wnt signaling and an induction of oncogenic properties in immortalized human Schwann cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e365a917fcd11f9e3331f28e9d12a11
https://doi.org/10.1158/2159-8290.22530717.v1
https://doi.org/10.1158/2159-8290.22530717.v1
Autor:
Rory L. Smoot, Sumera Rizvi, Chen Wang, Daniel R. O'Brien, Ayano Kabashima, Caitlin B. Conboy, Nathan W. Werneburg, EeeLN H. Buckarma
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451b60ea32ecf8af1c35765786e49fb1
https://doi.org/10.1158/1541-7786.22514280
https://doi.org/10.1158/1541-7786.22514280
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Table and Figure Legends-PDF file 123K, Supplementary Table and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccc12018854f2621735d0c850c71419
https://doi.org/10.1158/2159-8290.22530702.v1
https://doi.org/10.1158/2159-8290.22530702.v1