Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Caitlin A, Waddell"'
Autor:
Thomas D. J. Walker, Zahra F. Faraahi, Marcus J. Price, Amy Hawarden, Caitlin A. Waddell, Bryn Russell, Dominique M. Jones, Aiste McCormick, N. Gavrielides, S. Tyagi, Laura C. Woodhouse, Bethany Whalley, Connor Roberts, Emma J. Crosbie, Richard J. Edmondson
Publikováno v:
Walker, T D J, Faraahi, Z F, Price, M J, Hawarden, A, Waddell, C A, Russell, B, Jones, D M, McCormick, A, Gavrielides, N, Tyagi, S, Woodhouse, L C, Whalley, B, Roberts, C, Crosbie, E J & Edmondson, R J 2023, ' The DNA damage response in advanced ovarian cancer: functional analysis combined with machine learning identifies signatures that correlate with chemotherapy sensitivity and patient outcome ', British Journal of Cancer . https://doi.org/10.1038/s41416-023-02168-3
Background Ovarian cancers are hallmarked by chromosomal instability. New therapies deliver improved patient outcomes in relevant phenotypes, however therapy resistance and poor long-term survival signal requirements for better patient preselection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1280700fee921d034c284eae9e468e52
https://doi.org/10.1038/s41416-023-02168-3
https://doi.org/10.1038/s41416-023-02168-3
Autor:
David C. Hutchings, George W. P. Madders, Barbara C. Niort, Elizabeth F. Bode, Caitlin A. Waddell, Lori S. Woods, Katharine M. Dibb, David A. Eisner, Andrew W. Trafford
Publikováno v:
Hutchings, D, Madders, G, Niort, B, Bode, E, Waddell, C, Woods, L, Dibb, K, Eisner, D & Trafford, A 2022, ' Interaction of background Ca2+ influx, sarcoplasmic reticulum threshold and heart failure in determining propensity for Ca2+ waves in sheep heart ', JOURNAL OF PHYSIOLOGY-LONDON . https://doi.org/10.1113/JP282168
Key pointsHeart failure is a pro-arrhythmic state and arrhythmias are a major cause of death. At the cellular level, Ca2+ waves resulting in delayed after-depolarisations are a key trigger of arrhythmias. Ca2+ waves arise when the sarcoplasmic reticu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9002a54cd6ba1eab318aba7f54cc61
https://doi.org/10.1113/jp282168
https://doi.org/10.1113/jp282168
Background: Ovarian cancer remains the most lethal gynaecological malignancy and there is an urgent need for the development of further therapies to improve patient survival. Tumour infiltrating lymphocyte (TIL) therapy has shown clear efficacy in im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93f698d4572ec5ef8311566ed429c3b7
https://doi.org/10.21203/rs.3.rs-1477937/v1
https://doi.org/10.21203/rs.3.rs-1477937/v1
Autor:
David C, Hutchings, George W P, Madders, Barbara C, Niort, Elizabeth F, Bode, Caitlin A, Waddell, Lori S, Woods, Katharine M, Dibb, David A, Eisner, Andrew W, Trafford
Publikováno v:
The Journal of physiology. 600(11)
Ventricular arrhythmias can cause death in heart failure (HF). A trigger is the occurrence of Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd72b87e4e22f20df1b68556a95ab006
https://pubmed.ncbi.nlm.nih.gov/35476213
https://pubmed.ncbi.nlm.nih.gov/35476213