Výsledky vyhledávání - "Cairncross, JG"

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

Autor: Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJB, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E, Mirimanoff RO, Van Den Weyngaert D, Kaendler S, Krauseneck P, Vinolas N, Villa S, Wurm RE, Maillot MHB, Spagnolli F, Kantor G, Malhaire JP, Renard L, De Witte O, Scandolaro L, Vecht CJ, Maingon P, Lutterbach J, Kobierska A, Bolla M, Souchon R, Mitine C, Tzuk-Shina T, Kuten A, Haferkamp G, de Greve J, Priou F, Menten J, Rutten I, Clavere P, Malmstrom A, Jancar B, Newlands E, Pigott K, Twijnstra A, Chinot O, Reni M, Boiardi A, Fabbro M, Campone M, Bozzino J, Frenay M, Gijtenbeek J, Delattre JY, De Paula U, Hanzen C, Pavanato G, Schraub S, Pfeffer R, Soffietti R, Kortmann RD, Taphoorn M, Torrecilla JL, Grisold W, Huget P, Forsyth P, Fulton D, Kirby S, Wong R, Fenton D, Cairncross G, Whitlock P, Burdette-Radoux S, Gertler S, Saunders S, Laing K, Siddiqui J, Martin LA, Gulavita S, Perry J, Mason W, Thiessen B, Pai H, Alam ZY, Eisenstat D, Mingrone W, Hofer S, Pesce G, Dietrich PY, Thum P, Baumert B, Ryan G

Publikováno v: New England Journal of Medicine, vol. 352, no. 10, pp. 987-96
New England Journal of Medicine, 352(10), 987-996. Massachussetts Medical Society

BACKGROUND: Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to the extent feasible, followed by adjuvant radiotherapy. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf112f90a929a68afabcd377cbf792ea
https://doi.org/10.1056/NEJMoa043330

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Hyperpolarized C-13 MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring

Autor: Ronen, Sabrina, Chaumeil, MM, Radoul, M, Najac, C, Eriksson, P, Viswanath, P, Blough, MD, Chesnelong, C, Luchman, HA, Cairncross, JG, Ronen, SM

Publikováno v: Ronen, Sabrina; Chaumeil, MM; Radoul, M; Najac, C; Eriksson, P; Viswanath, P; et al.(2016). Hyperpolarized C-13 MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0pj5z00w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::8b2a6de0e123f066f861ca7f7f63fc2c
http://www.escholarship.org/uc/item/0pj5z00w

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PCV for Oligodendroglial Tumors: In Search of Prognostic Factors for Response and Survival

Autor: David Fortin, Cairncross Jg, David R. Macdonald, Larry Stitt

Publikováno v: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 28:215-223

PCV dans le traitement des tumeurs oligodendrogliales: a la recherche de facteurs pronostiques de la reponse et de la survie. Introduction: Nous rapportons des donnees sur la survie et les facteurs pronostiques de survie et de chimiosensibilite avant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c324236902c069c5ac86471904cf6f8
https://doi.org/10.1017/s0317167100001359

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Homozygous Deletions of theCDKN2C/p 18INK4CGene on the Short Arm of Chromosome 1 in Anaplastic Oligodendrogliomas

Autor: David N. Louis, Cairncross Jg, Ute Pohl

Publikováno v: Brain Pathol

Allelic deletions of the short arm of chromosome 1 are common in oligodendrogliomas and have been correlated with chemosensitivity and better prognosis in patients with high‐grade oligodendrogliomas. In these tumors, 1p loss is also inversely relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52efb5cb959a4c20778bbfa14339776
https://doi.org/10.1111/j.1750-3639.1999.tb00545.x

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The hPMS2 exon 5 mutation and malignant glioma

Autor: Cairncross Jg, Taylor, Magdalena C. Zlatescu, Yasushi Ino, David N. Louis, Schwartz M, Ang Lc, Janet Perry, Becker Le, Anat Stemmer-Rachamimov

Publikováno v: Journal of Neurosurgery. 90:946-950

✓ Patients with Turcot syndrome (TS) are predisposed to colon tumors and primary brain tumors, typically glioblastomas or medulloblastomas. The authors describe a patient with TS featuring a known germline mutation of exon 5 of the hPMS2 mismatch r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d35445c3527215f266c02399a11312
https://doi.org/10.3171/jns.1999.90.5.0946

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[Untitled]

Autor: Glenn Bauman, David R. Macdonald, Cairncross Jg, Barbara Fisher

Publikováno v: Journal of Neuro-Oncology. 38:83-89

Recurrence of malignant glioma following radiotherapy most commonly occurs in close proximity to the original contrast enhancing CT/MRI tumor volume. For this reason current radiation planning favors focal radiotherapy fields designed to cover the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10f1112f4275da2d13d3e27377286f92
https://doi.org/10.1023/a:1005985211037

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Treatment of malignant glioma in adults

Autor: Cairncross Jg, Forsyth Pa

Publikováno v: Current Opinion in Neurology. 8:414-418

Most patients with malignant glioma fare no better in 1995 than they did 30 years ago. However, high quality precision stereotactic biopsy is available in most centres, tumour resection is safer and more thorough than ever, focused radiation methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a1739cb08c03a7f7a80611ac29d425
https://doi.org/10.1097/00019052-199512000-00002

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Diffuse bilateral cerebral astrocytomas with atypical neuroimaging studies

Autor: Lisa R. Rogers, Weinstein Ma, Estes Ml, Cairncross Jg, Strachan T

Publikováno v: Journal of Neurosurgery. 81:817-821

✓ The authors describe the clinical behavior of eight patients with cerebral astrocytomas, in whom computerized tomography (CT) or magnetic resonance (MR) imaging of the brain was characterized by diffuse bilateral cerebral hemisphere tissue densit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcce316078f85fbdd423742569c0a3d
https://doi.org/10.3171/jns.1994.81.6.0817

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p53 Mutation, Expression, and DNA Ploidy in Evolving Gliomas: Evidence for Two Pathways of Progression

Autor: David A. Ramsay, M Keeney, Ann F. Chambers, A G Casson, Cairncross Jg, D. van Meyel

Publikováno v: JNCI Journal of the National Cancer Institute. 86:1011-1017

Background Two lines of evidence indirectly implicate the tumor suppressor p53 (also known as TP53) gene in glioma development. First, germline mutations of the p53 gene are associated with increased susceptibility to glioma. Second, chromosome 17p d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff5ab0450dbf36f3b79f542fac5ca93
https://doi.org/10.1093/jnci/86.13.1011

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Gliomas in Families

Autor: Cairncross Jg, G.L. Abdallah, R.M. Allaster, W.K. Cavenee, Y. Ikizler, David R. Macdonald, D.J. van Meyel, David A. Ramsay

Publikováno v: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 19:492-497

This is a descriptive study of 19 families with glial tumors. Twelve were identified prospectively from 178 consecutive, unrelated adults and children with newly diagnosed gliomas seen at a regional cancer center between 01 Jan 89 and 31 Mar 91 (6.7%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d082033ffc4c0bd3ea4c59be4dbab75a
https://doi.org/10.1017/s031716710004169x

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