Data from A Phase I Clinical, Pharmacokinetic, and Pharmacodynamic Study of Weekly or Every Three Week Ixabepilone and Daily Sunitinib in Patients with Advanced Solid Tumors

Autor: Jaime R. Merchan, Caio Rocha-Lima, Pasquale Benedetto, Jonathan C. Trent, Krisztina Kovacs, Aurea Flores, Deukwoo Kwon, Alberto J. Montero

Purpose: To evaluate the safety, MTD, pharmacokinetics/pharmacodynamics, and early clinical activity of ixabepilone given either weekly or every 3 weeks in combination with daily sunitinib in patients with advanced solid tumors.Experimental Design: E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca5ec88809267603808877f8531d143
https://doi.org/10.1158/1078-0432.c.6523437.v1

Exploring the role of ethnicity on perceptions of cancer and physical health recovery during the first year of survivorship

Autor: Youngmee Kim, Kelly M. Shaffer, Charles S. Carver, Alexis Milton, Caio Rocha-Lima

Publikováno v: Journal of Health Psychology. 21:1331-1338

This study examined the role of ethnicity (Black vs White) in the extent to which patients’ appraisal of the impact of cancer on themselves and their family members relates to their physical health. Colorectal cancer patients provided self-reports

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c000440e23d4a1deccd81836f01e27b
https://doi.org/10.1177/1359105314552304

Percutaneous Image-Guided Irreversible Electroporation for the Treatment of Unresectable, Locally Advanced Pancreatic Adenocarcinoma

Autor: Jose M. Yrizarry, Jaime R. Merchan, Isabelle C. Beulaygue, Govindarajan Narayanan, Joseph U. Levi, Ana Echenique, Tatiana Froud, Hester J. Scheffer, Peter J. Hosein, Elizabeth C. Hevert, Caio Rocha-Lima, Alan S. Livingstone, Riccardo Lencioni, Shree Venkat

Publikováno v: Journal of Vascular and Interventional Radiology, 28(3), 342-348. Elsevier Inc.
Narayanan, G, Hosein, P J, Beulaygue, I C, Froud, T, Scheffer, H J, Venkat, S R, Echenique, A M, Hevert, E C, Livingstone, A S, Rocha-Lima, C M, Merchan, J R, Levi, J U, Yrizarry, J M & Lencioni, R 2017, ' Percutaneous Image-Guided Irreversible Electroporation for the Treatment of Unresectable, Locally Advanced Pancreatic Adenocarcinoma ', Journal of Vascular and Interventional Radiology, vol. 28, no. 3, pp. 342-348 . https://doi.org/10.1016/j.jvir.2016.10.023

Purpose To describe safety and effectiveness of percutaneous irreversible electroporation (IRE) for treatment of unresectable, locally advanced pancreatic adenocarcinoma (LAPC). Materials and Methods This retrospective study included 50 patients (23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfac3e6391abdaafeacccd47c49ab766
https://pubmed.ncbi.nlm.nih.gov/27993507

A randomized, placebo-controlled phase 2 study of ganitumab (AMG 479) or conatumumab (AMG 655) in combination with gemcitabine in patients with metastatic pancreatic cancer

Autor: Edward B. Garon, Jesse McGreivy, Elwyn Loh, Y. J. Hei, D. Chan, Howard Safran, L.E. Garbo, Charles S. Fuchs, D. Richards, Hedy L. Kindler, Francesco Galimi, Sarah Bray, J.J. Stephenson, D.M. Kocs, E. G. Feigal, Caio Rocha-Lima

Publikováno v: Annals of Oncology. 23:2834-2842

Background We evaluated the efficacy and safety of ganitumab (a mAb antagonist of insulin-like growth factor 1 receptor) or conatumumab (a mAb agonist of human death receptor 5) combined with gemcitabine in a randomized phase 2 trial in patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc524a4c2b2cbc5ab7ee997f28ff51a4
https://doi.org/10.1093/annonc/mds142

Depressive symptoms among caregivers of colorectal cancer patients during the first year since diagnosis: a longitudinal investigation

Autor: Youngmee Kim, Charles S. Carver, Caio Rocha-Lima, Kelly M. Shaffer

Publikováno v: Psycho-Oncology. 22:362-367

Objective Few studies have examined prospectively and longitudinally depressive symptoms of family caregivers who provide care to colorectal cancer patients, and fewer have addressed ethnic minorities in this regard. This study investigated the relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b295dd1d86d5738ee3d7b48fe36addfd
https://doi.org/10.1002/pon.2100