Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Caio Bezerra Machado"'
Autor:
Renan Brito Gadelha, Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Laudreísa da Costa Pantoja, Igor Valentim Barreto, Rodrigo Monteiro Ribeiro, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 11, Pp 5498-5515 (2022)
The WD repeat containing antisense to TP53 (WRAP53) gene codifies an antisense transcript for tumor protein p53 (TP53), stabilization (WRAP53α), and a functional protein (WRAP53β, WDR79, or TCAB1). The WRAP53β protein functions as a scaffolding pr
Externí odkaz:
https://doaj.org/article/f98d24812b224b63af1ba3f66354a15f
Autor:
Igor Valentim Barreto, Flávia Melo Cunha de Pinho Pessoa, Caio Bezerra Machado, Laudreísa da Costa Pantoja, Rodrigo Monteiro Ribeiro, Germison Silva Lopes, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Lucas Eduardo Botelho de Souza, Rommel Mário Rodriguez Burbano, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Hematopoietic stem cells (HSCs) are known for their ability to proliferate and self-renew, thus being responsible for sustaining the hematopoietic system and residing in the bone marrow (BM). Leukemic stem cells (LSCs) are recognized by their stemnes
Externí odkaz:
https://doaj.org/article/d1b11a17fb2d438fbf02e483915c65cb
Autor:
Flávia Melo Cunha de Pinho Pessoa, Caio Bezerra Machado, Igor Valentim Barreto, Giulia Freire Sampaio, Deivide de Sousa Oliveira, Rodrigo Monteiro Ribeiro, Germison Silva Lopes, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Lucas Eduardo Botelho de Souza, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1098 (2023)
Acute myeloid leukemia (AML) is a hematologic malignancy that occurs due to alterations such as genetic mutations, chromosomal translocations, or changes in molecular levels. These alterations can accumulate in stem cells and hematopoietic progenitor
Externí odkaz:
https://doaj.org/article/69ec0988da82411ab1eb3f706fb99da4
Autor:
Igor Valentim Barreto, Caio Bezerra Machado, Davi Benevides Almeida, Flávia Melo Cunha de Pinho Pessoa, Renan Brito Gadelha, Laudreísa da Costa Pantoja, Deivide de Sousa Oliveira, Rodrigo Monteiro Ribeiro, Germison Silva Lopes, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, André Salim Khayat, Edivaldo Herculano Correa de Oliveira, Caroline Aquino Moreira-Nunes
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1784 (2022)
Multiple myeloma (MM) is a blood cell neoplasm characterized by excessive production of malignant monoclonal plasma cells (activated B lymphocytes) by the bone marrow, which end up synthesizing antibodies or antibody fragments, called M proteins, in
Externí odkaz:
https://doaj.org/article/a04c7cd0ccad49269e6904960a555f1b
Autor:
Ana Beatriz Aguiar Sanford, Leidivan Sousa da Cunha, Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Abigail Nayara dos Santos Silva, Rodrigo Monteiro Ribeiro, Fabiano Cordeiro Moreira, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, Lucas Eduardo Botelho de Souza, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8212 (2022)
The circadian clock (CC) is a daily system that regulates the oscillations of physiological processes and can respond to the external environment in order to maintain internal homeostasis. For the functioning of the CC, the clock genes (CG) act in di
Externí odkaz:
https://doaj.org/article/d017e81982084dbca588f847dcaf7bef
Autor:
Caio Bezerra Machado, Leidivan Sousa da Cunha, Jersey Heitor da Silva Maués, Flávia Melo Cunha de Pinho Pessoa, Marcelo Braga de Oliveira, Rodrigo Monteiro Ribeiro, Germison Silva Lopes, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5486 (2022)
Human T cell leukemia virus type 1 (HTLV-1) was identified as the first pathogenic human retrovirus and is estimated to infect 5 to 10 million individuals worldwide. Unlike other retroviruses, there is no effective therapy to prevent the onset of the
Externí odkaz:
https://doaj.org/article/767604f08b7d4483ae41ee334be3d823
Autor:
Flávia Melo Cunha de Pinho Pessoa, Caio Bezerra Machado, Emerson Lucena da Silva, Laudreísa da Costa Pantoja, Rodrigo Monteiro Ribeiro, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Raquel Carvalho Montenegro, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3830 (2022)
The increasing numbers of cancer cases worldwide and the exceedingly high mortality rates of some tumor subtypes raise the question about if the current protocols for cancer management are effective and what has been done to improve upon oncologic pa
Externí odkaz:
https://doaj.org/article/84d44ca51a43448a8042ba6d9f0241c7
Autor:
Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Emerson Lucena da Silva, Laudreísa da Costa Pantoja, Rodrigo Monteiro Ribeiro, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, Raquel Carvalho Montenegro, Rommel Mário Rodriguez Burbano, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1604 (2021)
Cancer is still a major barrier to life expectancy increase worldwide, and hematologic neoplasms represent a relevant percentage of cancer incidence rates. Tumor dependence of continuous proliferative signals mediated through protein kinases overexpr
Externí odkaz:
https://doaj.org/article/02c9551f195f4cee92efdae133b64a29
Autor:
Caroline Aquino Moreira-Nunes, Emerson Lucena da Silva, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Caio Bezerra Machado
Publikováno v:
Anticancer Research. 40:3055-3063
The idea of utilizing poly-ADP-ribose polymerase inhibitors (PARPi) as therapeutics for cancer has grown in popularity since its original approval for clinical usage in treatment of BRCA DNA repair-associated-mutated ovarian cancer. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1284782edb5fc06450eb8c26e8dda63d
https://doi.org/10.21873/anticanres.14286
https://doi.org/10.21873/anticanres.14286
Autor:
Beatriz Maria Dias Nogueira, Raquel Carvalho Montenegro, Caroline Aquino Moreira-Nunes, Caio Bezerra Machado, Maria Elisabete Amaral de Moraes
Publikováno v:
In Vivo
Telomeres compose the end portions of human chromosomes, and their main function is to protect the genome. In hematological disorders, telomeres are shortened, predisposing to genetic instability that may cause DNA damage and chromosomal rearrangemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea2e7d48d68ad413de798a352c28a80
https://doi.org/10.21873/invivo.12142
https://doi.org/10.21873/invivo.12142