Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Caining Jin"'
Autor:
Qi Jiang, Kun Huang, Yixin Zhang, Xin Kai, Kate Zhang, Benjamin Wei, Daniella Tatang, Stu Angus, Caining Jin, Changfeng Huang, Haishan Li, Qiaobing Xu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/a21377e2857d43f09fb86952c659aa3c
Autor:
Yota Yasumizu, Hasan Rajabi, Caining Jin, Tsuyoshi Hata, Sean Pitroda, Mark D. Long, Masayuki Hagiwara, Wei Li, Qiang Hu, Song Liu, Nami Yamashita, Atsushi Fushimi, Ling Kui, Mehmet Samur, Masaaki Yamamoto, Yan Zhang, Ning Zhang, Deli Hong, Takahiro Maeda, Takeo Kosaka, Kwok K. Wong, Mototsugu Oya, Donald Kufe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
MUC1-C is overexpressed in castration-resistant prostate cancer and neuroendocrine prostate cancer. Here, the authors show that MUC1-C drives lineage plasticity through MYC and BRN2, inducing neuroendocrine features and stemness in prostate cancer.
Externí odkaz:
https://doaj.org/article/122d971bc14145f181528834a1ae353b
Autor:
Yota Yasumizu, Hasan Rajabi, Caining Jin, Tsuyoshi Hata, Sean Pitroda, Mark D. Long, Masayuki Hagiwara, Wei Li, Qiang Hu, Song Liu, Nami Yamashita, Atsushi Fushimi, Ling Kui, Mehmet Samur, Masaaki Yamamoto, Yan Zhang, Ning Zhang, Deli Hong, Takahiro Maeda, Takeo Kosaka, Kwok K. Wong, Mototsugu Oya, Donald Kufe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/0c19cb2388fb444b9ecaa6c84f5deeb4
Autor:
Audrey Bouillez, Dennis Adeegbe, Caining Jin, Xiufeng Hu, Ashujit Tagde, Maroof Alam, Hasan Rajabi, Kwok-Kin Wong, Donald Kufe
Publikováno v:
OncoImmunology, Vol 6, Iss 9 (2017)
The cancer immune microenvironment is of importance for the effectiveness of immunotherapy; however, its dysregulation is poorly understood. The MUC1-C oncoprotein is aberrantly overexpressed in non-small cell lung cancer (NSCLC) and has been linked
Externí odkaz:
https://doaj.org/article/747e8e558ac24651b44a629deea789a1
Autor:
Caining Jin, Hasan Rajabi, Sean Pitroda, Ailing Li, Akriti Kharbanda, Ralph Weichselbaum, Donald Kufe
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39432 (2012)
Rab31 is a member of the Ras superfamily of small GTPases that has been linked to poor outcomes in patients with breast cancer. The MUC1-C oncoprotein is aberrantly overexpressed in most human breast cancers and also confers a poor prognosis. The pre
Externí odkaz:
https://doaj.org/article/dd38f6f2ece94e0f890d2d0eaf3c137e
PDF file - 338K, 293T cells were left untreated or treated with G0-203 each day for 4 days. The results (mean plus-minus SD of three replicates) are expressed as the percentage of cell death as determined by trypan blue staining on day 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98853ee9ef8cbecb3ccb66cf376949cc
https://doi.org/10.1158/1541-7786.22509643.v1
https://doi.org/10.1158/1541-7786.22509643.v1
Autor:
Donald Kufe, Mark D. Long, Song Liu, Henry Withers, Kwok-Kin Wong, Wenhao Suo, Zhou Luan, Yota Yasumizu, Masayuki Hagiwara, Caining Jin, Hasan Rajabi, Tatsuaki Daimon, Atrayee Bhattacharya, Nami Yamashita, Satoshi Ishikawa, Yoshihiro Morimoto, Atsushi Fushimi
Supplementary Figure from Dependence on the MUC1-C Oncoprotein in Classic, Variant, and Non–neuroendocrine Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5790caa7f84919492bc0965c704dcd60
https://doi.org/10.1158/1541-7786.22528077
https://doi.org/10.1158/1541-7786.22528077
PDF file - 622K, BT474/MUC1shRNA (A) and MCF-7/vector (B) cells were treated with fixed IC50 ratios of (i) GO-203 alone on days 0, 1, 2, 3 and 4, (ii) tamoxifen alone on days 0, 2 and 4 and (iii) the GO-203/tamoxifen combination. For tamoxifen-resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd462c93316129fccd21966da6b676d
https://doi.org/10.1158/1541-7786.22509640
https://doi.org/10.1158/1541-7786.22509640
Autor:
Donald Kufe, Mehmet Samur, Hidekazu Takahashi, Yozo Suzuki, Takahiro Maeda, Masayuki Hiraki, Masaaki Miyo, Deli Hong, Yota Yasumizu, Wei Li, Ling Kui, Yan Zhang, Rehan Ahmad, Caining Jin, Masaaki Yamamoto, Hasan Rajabi, Tsuyoshi Hata
The oncogenic MUC1-C protein and the TWIST1 epithelial–mesenchymal transition transcription factor (EMT-TF) are aberrantly expressed in triple-negative breast cancer (TNBC) cells. However, there is no known association between MUC1-C and TWIST1 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aff4e1a5166641a163063834450a1202
https://doi.org/10.1158/1535-7163.c.6537789.v1
https://doi.org/10.1158/1535-7163.c.6537789.v1
PDF file - 542K, A. MCF-7/MUC1-C cells were treated with 10 μM LY294002 (LY) for the indicated times. Lysates were immunoblotted with the indicated antibodies. B. MCF-7/MUC1-C cells were left untreated (Control) or treated with 10 μM LY294002 for 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa49d09c5dbb3364a18e3bf043530c29
https://doi.org/10.1158/1541-7786.22509649
https://doi.org/10.1158/1541-7786.22509649