Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Caineng Pan"'
Autor:
Dingqiao Wang, Jiangbo Liang, Jinguo Ye, Jingni Li, Jingpeng Li, Qikai Zhang, Qiuling Hu, Caineng Pan, Dongliang Wang, Zhong Liu, Wen Shi, Danli Shi, Fei Li, Bo Qu, Yingfeng Zheng
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e58041 (2024)
BackgroundLarge language models (LLMs) demonstrated advanced performance in processing clinical information. However, commercially available LLMs lack specialized medical knowledge and remain susceptible to generating inaccurate information. Given th
Externí odkaz:
https://doaj.org/article/f92183794e194de0b4a96c88988fe9d4
Autor:
Wen Shi, Jinguo Ye, Zhuoxing Shi, Caineng Pan, Qikai Zhang, Yuheng Lin, Dan Liang, Yizhi Liu, Xianchai Lin, Yingfeng Zheng
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Behect’s disease is a chronic vasculitis characterized by complex multi-organ immune aberrations. However, a comprehensive understanding of the gene-regulatory profile of peripheral autoimmunity and the diverse immune responses across dist
Externí odkaz:
https://doaj.org/article/b9daa3d7f2ef4f66934e5a5f164975ba
Autor:
Zhong Liu, Yanjing Huang, Dongliang Wang, Mengke Li, Qikai Zhang, Caineng Pan, Yuheng Lin, Yuanting Luo, Zhuoxing Shi, Ping Zhang, Yingfeng Zheng
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18324- (2023)
Aging is the strongest risk factor for cardiovascular disease, with progressive decline in the function of vascular endothelial cells (ECs) with age. Systematic analyses of the effects of aging on different cardiac EC types remain limited. Here, we c
Externí odkaz:
https://doaj.org/article/f632adafb2e9499daa47fc3b015198e5
Autor:
Mengke Li, Dongliang Wang, Zhong Liu, Yanjing Huang, Qikai Zhang, Caineng Pan, Yuheng Lin, Li Sun, Yingfeng Zheng
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Endothelial cells (ECs) with senescence-associated secretory phenotypes (SASP) have been identified as a key mechanism of aging that contributes to various age-related kidney diseases. In this study, we used single-cell RNA sequencing (scRNA-seq) to
Externí odkaz:
https://doaj.org/article/7f02a68878eb4fa6bc1cb6559aeef2f8
Autor:
Wen Shi, Jinguo Ye, Zhuoxing Shi, Caineng Pan, Qikai Zhang, Yuheng Lin, Yuanting Luo, Wenru Su, Yingfeng Zheng, Yizhi Liu
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Single-cell RNA-sequencing and chromatin accessibility analysis reveal transcriptomic and epigenomic changes between healthy patients and those affected by the systemic autoimmune disorder Vogt-Koyanagi-Harada disease.
Externí odkaz:
https://doaj.org/article/790a098b337f439191edcae216186188
Autor:
Dongliang Wang, Mengke Li, Jie Ling, Shuxia Chen, Qikai Zhang, Zhong Liu, Yanjing Huang, Caineng Pan, Yuheng Lin, Zhuoxing Shi, Ping Zhang, Yingfeng Zheng
Publikováno v:
Hepatology Communications, Vol 7, Iss 2, Pp e0021-e0021 (2023)
Endothelial cell (EC) function declines with age and contributes to the development of many vascular-related disease processes. Currently, the effects of aging on the molecular regulatory mechanisms of liver ECs have not been fully elucidated. Here,
Externí odkaz:
https://doaj.org/article/03a8008f7bae4722a96a5adbd2379fe7
Autor:
Wen Shi, Jinguo Ye, Zhuoxing Shi, Caineng Pan, Qikai Zhang, Yuheng Lin, Yuanting Luo, Wenru Su, Yingfeng Zheng, Yizhi Liu
Publikováno v:
Communications biology. 5(1)
The barrier to curing Vogt–Koyanagi–Harada disease (VKH) is thought to reside in a lack of understanding in the roles and regulations of peripheral inflammatory immune cells. Here we perform a single-cell multi-omic study of 166,149 cells in peri