Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Caiming Duan"'
Autor:
Daniela C. Oniciu, Sergey Denisenko, Ralf Mueller, Charles L Bisgaier, Krista L Hopson, Bruce H McCosar, Tian-Bao Huang, Lian Hao Zhang, Brian Goetz, Caiming Duan, Jing Yang, Clay T Cramer, Catherine Delaney Freiman, Jean-Louis H Dasseux, Otto J Geoffroy, Michael E Pape, Emil Pop
Publikováno v:
Journal of Medicinal Chemistry. 47:6082-6099
Keto-substituted hydrocarbons with 11-19 methylene and bis-terminal hydroxyl and carboxyl groups have been synthesized and evaluated in both in vivo and in vitro assays for their potential to favorably alter lipid disorders including metabolic syndro
Autor:
Anna Denisenko, Ralf Mueller, Catherine Delaney Freiman, Emil Pop, Krista L Hopson, Charles L Bisgaier, Tian-Bao Huang, Daniela C. Oniciu, Lian Hao Zhang, Brian Goetz, Jing Yang, Olga V Denisko, Jean-Louis H Dasseux, Michael E Pape, Caiming Duan, Clay T Cramer
Publikováno v:
Journal of Medicinal Chemistry. 47:5183-5197
Long hydrocarbon chain ethers with bis-terminal hydroxyl or carboxyl groups have been synthesized and evaluated for their potential to favorably alter lipid disorders including metabolic syndrome. Compounds were assessed for their effects on the de n
Autor:
Mary Ann A. Endoma, Tomas Hudlicky, Josephine W. Reed, Fengyang Yan, Edmond I. Eger, Caiming Duan, M. Hudlicky
Publikováno v:
Journal of Fluorine Chemistry. 102:363-367
Synthetic methods, especially those that use bromine trifluoride as a fluorinating agent, are described for the preparation of a number of fluorinated ethyl methyl ethers in good yield and high purity. In all cases, medium-scale syntheses (8–22 g)
Publikováno v:
Collection of Czechoslovak Chemical Communications. 65:561-569
3-(2-{6S-(2-Bromo-6-methoxyphenoxy)-5S-[tert-butyl(dimethyl)silyloxy)cyclohex-1-en-1-yl}ethyl)oxazol-2(3H)-one 14 was subjected to Heck cyclization conditions to afford diben- zofuran derivative 16. The comparison of stepwise vs cascade approaches to
Autor:
Mary Ann A. Endoma, Josephine W. Reed, M. Hudlicky, Edmond I. Eger, Caiming Duan, Fengyang Yan, Tomas Hudlicky
Publikováno v:
ChemInform. 31
Synthetic methods, especially those that use bromine trifluoride as a fluorinating agent, are described for the preparation of a number of fluorinated ethyl methyl ethers in good yield and high purity. In all cases, medium-scale syntheses (8–22 g)
Publikováno v:
Organic Letters. 1:2085-2087
β-Bromoethylbenzene was converted to the pentacycle 6 in 11 steps. The key features of this model were the toluene dioxygenase catalyzed production of diol 13 and the stereospecific Heck closure of 5 to 6.
Autor:
Andrew McKee, Lianhao Zhang, Stephen C Brown, Anna Denysenko, Charles L Bisgaier, Gregory J Fici, Tian-Bao Huang, Jean-Louis H Dasseux, Caiming Duan, Brian R. Krause, Brian Goetz, Michael E Pape, Daniela C. Oniciu, Janell M Lutostanski, Ralf Mueller, Narendra Lalwani, Clay T Cramer, Jing Yang, Sandra L Drake, Emil Pop
Publikováno v:
Journal of medicinal chemistry. 49(1)
A series of long (11-15) hydrocarbon chain diols and diacids with various central functional groups and terminal gem-dimethyl or -methyl/aryl substituents was synthesized and evaluated in both in vivo and in vitro assays for its potential to favorabl
Publikováno v:
ChemInform. 31
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Akademický článek
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