Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Caimin Xu"'
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Flavivirus replication occurs in membranous replication compartments, also known as replication organelles (ROs) derived from the host ER membrane. Our previous study showed that the non-structural (NS) protein 1 (NS1) is the essential factor for RO
Externí odkaz:
https://doaj.org/article/043afb8928e64b0290844cb58afd943c
Publikováno v:
BMB Reports, Vol 45, Iss 3, Pp 194-199 (2012)
Autophagy has been suggested as a possible mechanism fornon-apoptotic death despite evidence from many species thatautophagy represents a survival strategy of cells under stress.From our previous findings that supranutritional doses ofsodium selenite
Externí odkaz:
https://doaj.org/article/d0f8bb0b3f61433fb58e2cf51c5e9622
Publikováno v:
Cell chemical biology.
Flaviviruses have posed a serious threat to human health in the past decades, and effective therapeutic drugs are lacking; thus, treatment of flavivirus infection is a great challenge. The flavivirus protease NS2B3 is an attractive target for antivir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e819025166313af013d3a962bb8bafc7
https://pubmed.ncbi.nlm.nih.gov/36351431
https://pubmed.ncbi.nlm.nih.gov/36351431
Publikováno v:
Nucleic Acids Research
Zika virus is a positive single-strand RNA virus whose replication involved RNA unwinding and synthesis. ZIKV NS3 contains a helicase domain, but its enzymatic activity is not fully characterized. Here, we established a dsRNA unwinding assay based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001e4cfa72a327016ad6bb862ee0b8b9
https://doi.org/10.1093/nar/gkz650
https://doi.org/10.1093/nar/gkz650
Autor:
Caimin Xu, Nan Guo, Shuainan Liu, Sujuan Sun, Quan Liu, Caina Li, Miaomiao Yang, Guoliang Bai, Yi Huan, Xing Wang, Zhufang Shen
Publikováno v:
Food & Function. 9:6287-6297
Scope: Maltol (3-hydroxy-2-methy-4-pyrone), a potent antioxidative agent, typically is used to enhance flavor and preserve food. This study evaluated its effects on preventing diabetic peripheral neuropathy (DPN) in streptozotocin (STZ)-induced diabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc1b1d4da318c207cc536c0fb3bbdf1
https://doi.org/10.1039/c8fo01964a
https://doi.org/10.1039/c8fo01964a
Autor:
Cheng-Feng Qin, Na-Na Zhang, Caimin Xu, Yuqiang Niu, Zhong-Yu Liu, Lei Shi, Yali Ci, Wei Yang, Yang Yang
Publikováno v:
The Journal of Cell Biology
Zika virus induces the formation of vesicles from ER membrane that form viral replication factories in the ER lumen. Ci et al. show that the Zika NS1 protein plays a key role in this remodeling of the ER as the insertion of the hydrophobic regions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec75ec0753fa730d82fcb65498f986b5
https://doi.org/10.1083/jcb.201903062
https://doi.org/10.1083/jcb.201903062
Publikováno v:
Virus research. 275
Zika virus (ZIKV) is an emergent flavivirus associated with severe neurological disorders. ZIKV NS3 protein is a viral protease that cleaves the ZIKV polyprotein precursor into individual viral proteins. In this study, we found that ZIKV NS3 by itsel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9490865ea9fc49dfbc08a7ca542a9c7
https://pubmed.ncbi.nlm.nih.gov/31676367
https://pubmed.ncbi.nlm.nih.gov/31676367
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Viral fusion proteins are essential for enveloped virus infection. These proteins mediate fusion between the virus envelope and host cellular membrane to release the viral genome into cells. Vesicular stomatitis virus G (VSV G) protein is a typical t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c12fb4d70b78f494d93e14e85be62e3
https://doi.org/10.1038/s41598-018-28868-y
https://doi.org/10.1038/s41598-018-28868-y
Publikováno v:
Oncology Reports
In the present study, we aimed to investigate the relationship between autophagy and apoptosis in selenite‑treated colorectal cancer (CRC) cells. The effects of selenite on HCT116 and SW480 cell apoptosis were investigated with an Annexin V/propidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c346461d5a98687c7c655f4eaa62aa
https://doi.org/10.3892/or.2015.4484
https://doi.org/10.3892/or.2015.4484
Autor:
Pa Wu, Yang Yang, Lei Shi, Kaiyan Hui, Caimin Xu, Jiajia An, Jing Duan, Yali Ci, Hui Luo, Kejian Shi
Publikováno v:
Cancer Letters. 354:189-199
Supranutritional selenite has anti-cancer therapeutic effects in vivo; however, the detailed mechanisms underlying these effects are not clearly understood. Further studies would broaden our understanding of the anti-cancer effects of this compound a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb164ec07431299126400b223d841f1
https://doi.org/10.1016/j.canlet.2014.08.009
https://doi.org/10.1016/j.canlet.2014.08.009