iPSC-derived cortical neurons to study sporadic Alzheimer disease: A transcriptome comparison with post-mortem brain samples

Autor: Verheijen, M.C.T, Krauskopf, J., Caiment, F., Nazaruk, M., Wen, Q.F., van Herwijnen, M.H.M., Hauser, D.A., Gajjar, M., Verfaillie, C., Vermeiren, Y., De Deyn, P.P., Wittens, M.M.J., Sieben, A., Engelborghs, S., Dejonckheere, W., Princen, K., Griffioen, G., Roggen, E.L., Briedé, J.J.

Publikováno v: In Toxicology Letters 1 March 2022 356:89-99

IsoTools: a flexible workflow for long-read transcriptome sequencing analysis

Autor: Lienhard, M., https://orcid.org/0000-0002-2549-3142, van den Beucken , T., Timmermann, B., Hochradel, M., Boerno, S., https://orcid.org/0000-0002-7990-9625, Caiment , F., Vingron, M., https://orcid.org/0000-0002-1765-4241, Herwig, R., https://orcid.org/0000-0002-9335-1760

Publikováno v: Bioinformatics

MotivationLong-read transcriptome sequencing (LRTS) has the potential to enhance our understanding of alternative splicing, and the complexity of this process requires the use of versatile computational tools, with the ability to accommodate various

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1874::bf182269dfe89994eff5518b581e09a4
https://hdl.handle.net/21.11116/0000-000D-4F70-D21.11116/0000-000D-4F6E-1

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Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds

Autor: Verheijen, M., Sarkans, U., Wolski, W., Jennen, D., Caiment , F., Kleinjans, J., HeCaToS , C., Barel, G., Boerno, S., Herwig, R., Lienhard, M., Timmermann, B.

Publikováno v: Castell Ripoll, José Vicente Verheijen, Marcha Sarkans, Ugis Jennen, Danyel Caiment, Florian Kleinjans, Jos Wolski, Witold 2022 Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds. Scientific Data 9 699 1 11
Scientific data 9, 699 (2022). doi:10.1038/s41597-022-01825-1
Scientific Data
Scientific data, 9(1). Nature Publishing Group
Scientific Data, 9 (1)

The data currently described was generated within the EU/FP7 HeCaToS project (Hepatic and Cardiac Toxicity Systems modeling). The project aimed to develop an in silico prediction system to contribute to drug safety assessment for humans. For this pur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f276a79a91bd92a2ab684a95a02aa37
https://hdl.handle.net/10550/87180

P08-09: Dependence of Developmental Toxicity for Polyaromatic Hydrocarbons on Aryl Hydrocarbon Receptor: a case study with Benzo(a)Pyrene

Autor: Deferme, L., Kocabas, N.A., North, C., Caiment, F.

Publikováno v: In Toxicology Letters September 2023 384 Supplement 1:S128-S128