Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Cailong Fang"'
Autor:
Cailong Fang, Keri Tochiki, Qiu Meng, Sun Ying, Victoria Reay, Christopher Corrigan, Tak H. Lee, Huifen Wu, Rahilya L Napoli
Publikováno v:
Journal of Allergy and Clinical Immunology. 129:1636-1646
Background Prostaglandin E 2 (PGE 2 ) is thought to play a role in the pathogenesis of aspirin-sensitive asthma (ASA). Objective We sought to extend our previous observations implicating impaired inflammatory cell responsiveness to PGE 2 as a pathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fc77d9aac826e963d455cfca97e0c3
https://doi.org/10.1016/j.jaci.2012.02.007
https://doi.org/10.1016/j.jaci.2012.02.007
Publikováno v:
Expert Opinion on Drug Discovery. 6:1027-1044
Inhaled corticosteroids alone or with long-acting beta-2 agonists (LABA) are the basic treatment for stable asthma. While the majority of patients are controllable, some patients retain chronic severe disease and develop permanent alterations in airw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925408ee38db2f68a09c865c9512a8f3
https://doi.org/10.1517/17460441.2011.608659
https://doi.org/10.1517/17460441.2011.608659
Autor:
Wei Wang, Sun Ying, Cailong Fang, A. Barry Kay, Yunqing An, Tak H. Lee, Christopher Corrigan, Qiu Meng, M. Rosario Caballero, Ghada Eid, Yui-Hsi Wang, Z. Lv, Yong-Jun Liu
Publikováno v:
Journal of Allergy and Clinical Immunology. 128:116-124
IL-25 is thought to participate in allergic inflammation by propagating T(h)2-type responses.To address the hypothesis that allergen provocation increases expression of IL-25 and its receptor IL-25R in the asthmatic bronchial mucosa and skin dermis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efef32798ef9e545bf99983f0a96650d
https://doi.org/10.1016/j.jaci.2011.03.043
https://doi.org/10.1016/j.jaci.2011.03.043
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis. 58:81-90
Thymic stromal lymphopoietin (TSLP) primes dendritic cells to promote a Th2 inflammatory response. Its action is mediated by a heterodimeric receptor which consists of the interleukin-7 receptor alpha chain and the TSLP receptor chain (TSLPR). TSLPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622783e5c6808b987aff5b15fb0eff1f
https://doi.org/10.1007/s00005-010-0064-3
https://doi.org/10.1007/s00005-010-0064-3
Publikováno v:
Inflammation & Allergy-Drug Targets. 7:119-128
Asthma is a chronic disease characterised by airways hyperresponsiveness, airways inflammation, airways remodelling and reversible airways obstruction. Airway structural cells, recruited inflammatory cells and many mediators such as cytokines, chemok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c321211ff104b66a90e77493c19a8f97
https://doi.org/10.2174/187152808785107624
https://doi.org/10.2174/187152808785107624
Publikováno v:
Journal of Vascular and Interventional Radiology. 27:S145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58755bbd05a55dacaedbae2419b530f
https://doi.org/10.1016/j.jvir.2015.12.378
https://doi.org/10.1016/j.jvir.2015.12.378
Autor:
Wei Wang, Kewu Huang, Cailong Fang, Xiujuan Yao, Sun Ying, Tak H. Lee, Yunqing An, Christopher Corrigan, Qiu Meng, Y. Q. Fan, Z. Lv
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 42(11)
SummaryBackground Unlike other IL-17 family members, the Th2-derived cytokine IL-25 (IL-17E) induces (promotes) Th2 responses. One or both of the two receptors for IL-25 (IL-17RA, IL-17RB) is expressed on inflammatory cells and tissue structural cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c368673c2d645cd37992e1411f4edd
https://pubmed.ncbi.nlm.nih.gov/23106660
https://pubmed.ncbi.nlm.nih.gov/23106660
Autor:
G. Zhang, C.J. Corrigan, H. F. Wu, K. Huang, Tak H. Lee, G. Eid, Q. Meng, Sun Ying, Cailong Fang, X. Zhang, S. Yang
Publikováno v:
The European respiratory journal. 39(2)
Though implicated in vascular remodelling, a role for the resistin-like molecule (RELM)-β in human airway remodelling remains unexplored. We hypothesised that RELM-β expression is increased in the airways of asthmatics and regulates airways epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9431ef79953599ac66bff71ea8a6d577
https://pubmed.ncbi.nlm.nih.gov/21828035
https://pubmed.ncbi.nlm.nih.gov/21828035
Autor:
Cailong Fang, Sun Ying, Z. Lv, Wei Wang, Yiqiang Fan, Yui Hsi Wang, Yong-Jun Liu, Christopher Corrigan, Victoria Reay, Yunqing An, Tak H. Lee, Huifen Wu, Qiu Meng
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(4)
IL-25 (IL-17E) is a T-helper cell type 2 (Th2) cytokine best described as a potentiator of Th2 memory responses. Reports of expression of its receptor, IL-25R, on airways structural cells suggest a wider role for IL-25 in remodeling. We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e3dbfed270a88c2a5ad4207f88c5b0
https://pubmed.ncbi.nlm.nih.gov/21205894
https://pubmed.ncbi.nlm.nih.gov/21205894
Autor:
Christopher Corrigan, Betty Shamji, Qiu Meng, Matthew J. Edwards, Zhongli Gao, David J. Cousins, Brian J. O'Connor, Sun Ying, Jonathan Ratoff, Cailong Fang, Guizhen Zhang, Shuyan Gu, Tak H. Lee
Publikováno v:
King's College London
Scopus-Elsevier
Scopus-Elsevier
Asthma and chronic obstructive pulmonary disease (COPD) are associated with Th2 and Th1 differentiated T cells. The cytokine thymic stromal lymphopoietin (TSLP) promotes differentiation of Th2 T cells and secretion of chemokines which preferentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f74c2121461356015be1f4743928af4
https://pubmed.ncbi.nlm.nih.gov/18684970
https://pubmed.ncbi.nlm.nih.gov/18684970