Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Cailing, Gan"'
Autor:
Qun Wei, Cailing Gan, Meng Sun, Yuting Xie, Hongyao Liu, Taixiong Xue, Conghui Deng, Chunheng Mo, Tinghong Ye
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-30 (2024)
Abstract Fibrosis is an excessive wound-healing response induced by repeated or chronic external stimuli to tissues, significantly impacting quality of life and primarily contributing to organ failure. Organ fibrosis is reported to cause 45% of all-c
Externí odkaz:
https://doaj.org/article/3b69c5d2e6cb4cce925f11611ff9ec65
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-35 (2024)
Abstract The FGFR signaling pathway is integral to cellular activities, including proliferation, differentiation, and survival. Dysregulation of this pathway is implicated in numerous human cancers, positioning FGFR as a prominent therapeutic target.
Externí odkaz:
https://doaj.org/article/5b180a562f544a33a0148e209a3c1244
Autor:
Cailing Gan, Yan Wang, Zhongzheng Xiang, Hongyao Liu, Zui Tan, Yuting Xie, Yuqin Yao, Liang Ouyang, Changyang Gong, Tinghong Ye
Publikováno v:
Journal of Advanced Research, Vol 51, Iss , Pp 109-120 (2023)
Introduction: Idiopathic pulmonary fibrosis (IPF), a life-threatening interstitial lung disease, is characterized by excessive activation and proliferation of fibroblasts and epithelial-mesenchymal transition (EMT) of alveolar epithelial cells (AEC)
Externí odkaz:
https://doaj.org/article/40640b8d9c934be68f51732f444d8e67
Autor:
Cailing Gan, Qianyu Zhang, Hongyao Liu, Guan Wang, Liqun Wang, Yali Li, Zui Tan, Wenya Yin, Yuqin Yao, Yongmei Xie, Liang Ouyang, Luoting Yu, Tinghong Ye
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a serious interstitial lung disease with a complex pathogenesis and high mortality. The development of new drugs is time-consuming and laborious; therefore, research on the new use of old dru
Externí odkaz:
https://doaj.org/article/17651d1e590c4bfb8b43eaf44abeb2a7
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal, and chronic lung disease, lacking a validated and effective therapy. Blueberry has demonstrated multiple pharmacological activities including anti-inflammatory, antioxidant, and anticancer.
Externí odkaz:
https://doaj.org/article/f89fef1df9d742009f752b31c1f768d3
Autor:
Zui Tan, Hongbao Sun, Taixiong Xue, Cailing Gan, Hongyao Liu, Yuting Xie, Yuqin Yao, Tinghong Ye
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Liver fibrosis is an abnormal wound repair response caused by a variety of chronic liver injuries, which is characterized by over-deposition of diffuse extracellular matrix (ECM) and anomalous hyperplasia of connective tissue, and it may further deve
Externí odkaz:
https://doaj.org/article/1a257aab5d2044be8d2387b29be0facd
Autor:
Yuting Xie, Lin Yue, Yaojie Shi, Xingping Su, Cailing Gan, Hongyao Liu, Taixiong Xue, Tinghong Ye
Publikováno v:
Journal of Medicinal Chemistry. 66:4342-4360
Autor:
Yali Li, Cailing Gan, Yange Zhang, Yan Yu, Chen Fan, Yuanle Deng, Qianyu Zhang, Xi Yu, Yiwen Zhang, Liqun Wang, Fang He, Yongmei Xie, Tinghong Ye, Wenya Yin
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Background: Breast cancer is the most common female cancer with considerable metastatic potential, which urges the need for developing novel potential drug candidate to inhibit tumor metastasis. Signal transducer and activator of transcription 3 (Sta
Externí odkaz:
https://doaj.org/article/e8a7a2bf20d24252b17e6c8ff338dca8
Autor:
Taixiong Xue, Lin Yue, Guonian Zhu, Zui Tan, Hongyao Liu, Cailing Gan, Chen Fan, Xingping Su, Yuting Xie, Tinghong Ye
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver.
Liver fibrosis is an excessive wound-healing response governed by activated hepatic stellate cells (HSCs). To date, there is no drug available for liver fibrosis. Although ferulic acid (FA) has multiple pharmacological functions, its anti-hepatic fib
Autor:
Yijie Wang, Hongyao Liu, Wenzhen Li, Yuting Xie, Cailing Gan, Taixiong Xue, Xingping Su, Lin Yue, Qin Wang, Chen Fan, Yiwen Zhang, Tinghong Ye
Publikováno v:
European journal of medicinal chemistry. 246
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease of unknown aetiology with limited treatment options. Currently, only two drugs, nintedanib and pirfenidone, are approved for the clinical treatment of IPF, but their efficacie