Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Caili Xu"'
Autor:
Wenjing Xue, Caili Xu, Kaiqi Zhang, Lu Cui, Xiting Huang, Yanyang Nan, Dianwen Ju, Xusheng Chang, Xuyao Zhang
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Claudin18.2 (CLDN18.2) is overexpressed in cancers of the digestive system, rendering it an ideal drug target for antibody-drug conjugates (ADCs). Despite many CLDN18.2-directed ADCs undergoing clinical trials, the inconclusive underlying me
Externí odkaz:
https://doaj.org/article/1c6884e23f074c82bad904974747cf43
Autor:
Caili Xu, Min Zhu, Qian Wang, Jiajun Cui, Yuping Huang, Xiting Huang, Jing Huang, Junwei Gai, Guanghui Li, Peng Qiao, Xian Zeng, Dianwen Ju, Yakun Wan, Xuyao Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Pancreatic cancer is a highly aggressive malignancy with limited treatment options and a poor prognosis. Trophoblast cell surface antigen 2 (TROP2), a cell surface antigen overexpressed in the tumors of more than half of pancreati
Externí odkaz:
https://doaj.org/article/a6f48e10988c48baa5b2ad23aeba0f2d
Autor:
Yuting Zhang, Weijuan Xin, Xiaozhi Hu, Hanqi Wang, Xiaomiao Ye, Caili Xu, Yanyang Nan, Zhengyu Wu, Dianwen Ju, Jiajun Fan
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-11 (2023)
Abstract Macrophages are the origin of most foam cells in the early stage of atherosclerotic plaques. However, the mechanism involved in the formation of macrophage-derived foam cell formation remains unclear. Here, we revealed that the hedgehog (Hh)
Externí odkaz:
https://doaj.org/article/8467d5e7cf3b48dbb5475d6c97d4b959
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/65d0a200df28493cb51f2014c7623485
Autor:
Xiaozhi Hu, Jiajun Fan, Qianqian Ma, Lei Han, Zhonglian Cao, Caili Xu, Jingyun Luan, Guangjun Jing, Yanyang Nan, Tao Wu, Yuting Zhang, Hanqi Wang, Yuanzhen Zhang, Dianwen Ju
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is a metabolic disease mainly on account of hypercholesterolemia and may progress to cirrhosis and hepatocellular carcinoma. The discovery of effective therapy for NAFLD is an essential unm
Externí odkaz:
https://doaj.org/article/5dbeba4e36234562bc58ecedb43f8322
Autor:
Yichen Wang, Xuyao Zhang, Caili Xu, Yanyang Nan, Jiajun Fan, Xian Zeng, Byoung S. Kwon, Dianwen Ju
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionAlthough PD-1/L1 mAb has demonstrated clinical benefits in certain cancer types, low response rate and resistance remain the main challenges for the application of these immune checkpoint inhibitors (ICIs). 4-1BB is a co-stimulator molecu
Externí odkaz:
https://doaj.org/article/526d979fc550427ca12da3dbd2615014
Autor:
Xiaomiao Ye, Peng Zhang, Yuting Zhang, Jingyun Luan, Caili Xu, Zhengyu Wu, Dianwen Ju, Wei Hu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundGasdermin D (GSDMD) plays an essential role in the pathway of pyroptosis. However, whether GSDMD participates in myocardial ischaemia/reperfusion injury (MI/RI) remains poorly understood.MethodsSerum levels of GSDMD and IL-18 in ST-segment
Externí odkaz:
https://doaj.org/article/4a0b8c61fe0f4f8aba192dcda567c285
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As nano-sized materials prepared by isolating, disrupting and extruding cell membranes, cellular vesicles are emerging as a novel vehicle for immunotherapeutic drugs to activate antitumor immunity. Cell membrane-derived vesicles inherit the surface c
Externí odkaz:
https://doaj.org/article/24127772a489405a99f77b7eb5272be2
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic kidney injury has gradually become a worldwide public health problem currently affecting approximately 10% of the population and can eventually progress to chronic end-stage renal disease characteristic by the result of epithelial atrophy. In
Externí odkaz:
https://doaj.org/article/59f82dc3e77d4c82b3165fb2d888edda
Autor:
Renliang Lyu, Zeqin Li, Cheng Liang, Cheng Zhang, Ting Xia, Ming Wu, Yi Wang, Lichun Wang, Xiaogang Luo, Caili Xu
Publikováno v:
Carbohydrate Polymer Technologies and Applications, Vol 2, Iss , Pp 100144- (2021)
In this work, due to its excellent adsorption performance, biodegradability, and low toxicity, chitosan was used as the raw material to synthesize a series of new oil-in-water (O/W) type crude oil demulsifiers. First, an acyl group was introduced ont
Externí odkaz:
https://doaj.org/article/9ed22b57068d430a8aa4ba585df05f5b