Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Caijing Han"'
Autor:
Caijing Han, Xiaoting Kong, Xiaohong Xia, Xinyu Huang, Zhaojie Mao, Jiaxin Han, Fuyan Shi, Yaohui Liang, Anning Wang, Fengxiang Zhang
Publikováno v:
Journal of Functional Foods, Vol 111, Iss , Pp 105897- (2023)
Ginseng peptide (GP) (100, 200, 400 mg/kg bw) lowered blood glucose levels, explored the relationship between GP and gut microbiota-based hypoglycemic effects. GP significantly reduced fasting blood glucose levels (25.38–13.37 mM), improved insulin
Externí odkaz:
https://doaj.org/article/5687bb08d25e408e8055152a353a4ffe
Autor:
Zhijie Chen, Yu Fu, Shimeng Liu, Xinyu Huang, Xiaoting Kong, Zhaojie Mao, Ning Hu, Fengxiang Zhang, Caijing Han
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e13133- (2023)
Aspartokinase (AK) is synergistically suppressed by Thr and Lys in the Corynebacterium metabolic pathway. Site-directed mutations can significantly improve AK inhibition. Our previous studies confirmed that sites 379 and 380 were important sites affe
Externí odkaz:
https://doaj.org/article/75565499114344beb99c251af9bc5c29
Autor:
Caijing Han, Bingjie Lin, Xinyu Huang, Zhaojie Mao, Xiaoting Kong, Lei Fang, Peng Xue, Anning Wang, Fengxiang Zhang
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105721- (2023)
Summary: To improve the treatment of pigmentation disorders, looking for natural and safe inhibitors of melanin synthesis has become an area of research interest. The quinoa husk peptides reportedly elicit various biological activities (e.g., anti-ca
Externí odkaz:
https://doaj.org/article/c739e8b1f175441c996ec70736de0f0d
Autor:
Anwei Cheng, Haiqing Yan, Caijing Han, Xiangyan Chen, Wenliang Wang, Chunyang Xie, Jingran Qu, Zhiqing Gong, Xianquan Shi
Publikováno v:
Czech Journal of Food Sciences, Vol 32, Iss 3, Pp 218-225 (2014)
Polyphenols, including extractable polyphenols (EPP) and non-extractable polyphenols (NEPP), are natural and secondary metabolic substances in plants that have beneficial properties to human health. However, NEPP associated with dietary fiber and pro
Externí odkaz:
https://doaj.org/article/6d742452bf024f7f9f1520a1ab1bdd07
Publikováno v:
Molecules, Vol 23, Iss 12, p 3379 (2018)
In this study, a novel monomer aspartokinase (AK) from Corynebacterium pekinense was identified, and its monomer model was constructed. Site 380 was identified by homologous sequencing and monomer model comparison as the key site which was conserved
Externí odkaz:
https://doaj.org/article/ed775d78891c45d8819fbb8747ecede3
Publikováno v:
Bioprocess and Biosystems Engineering. 45:541-551
This study aimed to improve the catalytic activity of aspartate kinase (AK), the first key rate-limiting enzyme in the aspartic acid metabolism pathway, by site-directed saturation mutagenesis, and to weaken the synergistic feedback inhibition of met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6262ff43c0baa9d61592381ae452999
https://doi.org/10.1007/s00449-021-02677-6
https://doi.org/10.1007/s00449-021-02677-6
Autor:
Yanan Wang, Zhanqing Fan, Liu Xiaoting, Li Fang, Weihong Min, Shi Junhua, Caijing Han, Xin Gao
Publikováno v:
RSC Advances. 11:30-38
In microorganisms and plants, aspartate kinase (AK) is the initial committed enzyme of the biosynthesis of the aspartate acid family amino acids and is inhibited by end products. In the paper, we mutated the key allosteric regulatory site A380 around
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f835c8e358ae96aa41f0f62faa4cff
https://doi.org/10.1039/d0ra09153g
https://doi.org/10.1039/d0ra09153g
Autor:
Caijing Han, Bingjie Lin, Zhaojie Mao, Xiaoting Kong, Xinyu Huang, Lei Fang, Peng Xue, Anning Wang, Fengxiang Zhang
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dcb6b92ee1db80c55cc578689759d0a
https://doi.org/10.2139/ssrn.4141632
https://doi.org/10.2139/ssrn.4141632
Autor:
Zhijie Chen, Yu Fu, Shimeng Liu, Xiaoting Kong, Zhaojie Mao, Ning Hu, Fengxiang Zhang, Caijing Han
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1c58c6c8a7deb607780688144369b5d
https://doi.org/10.2139/ssrn.4198933
https://doi.org/10.2139/ssrn.4198933
Publikováno v:
Process Biochemistry. 83:77-85
Aspartokinase (AK) is known to be inhibited by the synergistic feedback of threonine and lysine in the relevant biosynthesis pathway in Corynebacterium, thereby hindering downstream metabolite accumulation. In this study, site-directed mutagenesis wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1688c0559169508e81b66a31e02629d
https://doi.org/10.1016/j.procbio.2019.04.022
https://doi.org/10.1016/j.procbio.2019.04.022