Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Caijiao Yi"'
Autor:
Wen Deng, Caijiao Yi, Wei Pan, Jian Liu, Jinyan Qi, Juan Chen, Zengchao Zhou, Yiqin Duan, Xiangyan Ning, Jun Li, Changhua Ye, Zhongping Chen, Heping Xu
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Neovascular age-related macular degeneration (nAMD) is a major cause of blindness in the elderly. The disease is due to the growth of abnormal blood vessels into the macula, leading to the loss of central vision. Intravitreal inje
Externí odkaz:
https://doaj.org/article/4bd46dc3d8fe4c619319235d4910ee48
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Retinal fibrosis affects 40–70% of neovascular age-related macular degeneration patients. This study investigated the effect of ageing on subretinal fibrosis secondary to choroidal neovascularization and the mechanism of action.
Externí odkaz:
https://doaj.org/article/4f70066f414a4c548b304364dbfaac26
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background Macular subretinal fibrosis is the end-stage complication of neovascular age-related macular degeneration (nAMD). We previously developed a mouse model of two-stage laser-induced subretinal fibrosis that mimics closely the dynamic
Externí odkaz:
https://doaj.org/article/51567d6921f64869927aa75b94ddbcd0
Publikováno v:
Investigative Ophthalmology & Visual Science
Liu, J, Yi, C, Ming, W, Tang, M, Tang, X, Luo, C, Lei, B, Chen, M & Xu, H 2021, ' Retinal pigment epithelial cells express antimicrobial peptide lysozyme-a novel mechanism of innate immune defense of the blood-retina barrier ', Investigative Ophthalmology and Visual Science, vol. 62, no. 7, 21 . https://doi.org/10.1167/iovs.62.7.21
Liu, J, Yi, C, Ming, W, Tang, M, Tang, X, Luo, C, Lei, B, Chen, M & Xu, H 2021, ' Retinal pigment epithelial cells express antimicrobial peptide lysozyme-a novel mechanism of innate immune defense of the blood-retina barrier ', Investigative Ophthalmology and Visual Science, vol. 62, no. 7, 21 . https://doi.org/10.1167/iovs.62.7.21
Purpose: For this study we aimed to understand if retinal pigment epithelial (RPE) cells express antimicrobial peptide lysozyme as a mechanism to protect the neuroretina from blood-borne pathogens.Methods: The expression of lysozyme in human and mous