Výsledky vyhledávání - "Caihong X. Li"

Distinct nuclear and cytoplasmic functions of androgen receptor cofactor p44 and association with androgen-independent prostate cancer

Autor: Zhengxin Wang, Alice Feng, Caihong X. Li, Yi Peng, Michael J. Garabedian, Peng Lee, Jianjun Wei, Luis Chiriboga, Fei Chen, Maureen McLeod, Robert G. Roeder, Yirong Li, Xiangtian Kong, Jonathan Melamed

Publikováno v: Proceedings of the National Academy of Sciences. 105:5236-5241

Androgen receptor (AR) mediates transcriptional activation of diverse target genes through interactions with various coactivators that may alter its function and help mediate the switch between prostate cell proliferation and differentiation. We rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6b62d0642b430f46e3eca30593aca6
https://doi.org/10.1073/pnas.0712262105

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Decrease in stromal androgen receptor associates with androgen-independent disease and promotes prostate cancer cell proliferation and invasion

Autor: Paul D. Walden, Caihong X. Li, Jianjun Wei, Yirong Li, Huihui Ye, Jinsong Liu, Michael J. Garabedian, Zhengxin Wang, Jonathan Melamed, Peng Lee, Yi Peng, Hui C. Tsou, Fei Chen

Publikováno v: Journal of Cellular and Molecular Medicine

Androgen receptor (AR) is expressed in both stromal and epithelial cells of the prostate. The majority of studies on AR expression and function in prostate cancer is focused on malignant epithelial cells rather than stromal cells. In this study, we e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e851391f2da854dc1c2af246790b969f
https://doi.org/10.1111/j.1582-4934.2008.00279.x

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Genetic and Biochemical Evaluation of the Importance of Cdc6 in Regulating Mitotic Exit

Autor: Vincent Archambault, Michael P. Rout, Alan J. Tackett, Brian T. Chait, Caihong X. Li, Frederick R. Cross, Ralph Wäsch

Publikováno v: Molecular Biology of the Cell. 14:4592-4604

We evaluated the hypothesis that the N-terminal region of the replication control protein Cdc6 acts as an inhibitor of cyclin-dependent kinase (Cdk) activity, promoting mitotic exit. Cdc6 accumulation is restricted to the period from mid-cell cycle u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034c141d51a957e5bd16cabebe301b25
https://doi.org/10.1091/mbc.e03-06-0384

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Stimulation of prostate cancer cellular proliferation and invasion by the androgen receptor co-activator ARA70

Autor: Michael J. Garabedian, Zhengxin Wang, Jonathan Melamed, Jianjun Wei, Martin Ligr, William L. Gerald, Caihong X. Li, Fei Chen, Yi Peng, Peng Lee, Michele Pagano

Publikováno v: The American journal of pathology. 172(1)

ARA70 was first identified as a gene fused to the ret oncogene in thyroid carcinoma and subsequently as a co-activator for androgen receptor (AR). Two isoforms of ARA70 have been identified: a 70-kDa version called ARA70 alpha and an internally splic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0e679cba1cdcdb40aaca29842597f5
https://pubmed.ncbi.nlm.nih.gov/18471560

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Androgen receptor and prostate apoptosis response factor-4 target the c-FLIP gene to determine survival and apoptosis in the prostate gland

Autor: Peng Lee, Hua Wang, Liran Zhou, Fahao Zhang, Zhengxin Wang, Caihong X. Li, Jonathan Melamed, Hong Wu, Shen Gao

Publikováno v: Journal of molecular endocrinology. 36(3)

Androgen receptor (AR) is a ligand-activated transcription factor that mediates the action of androgens and is essential for the growth, function, and cell differentiation of the prostate gland. Here, we demonstrated that the prostate apoptosis respo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f437959e60d1a9cfc073db11be2b984
https://pubmed.ncbi.nlm.nih.gov/16720717

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