Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Caiguo Zhang"'
Autor:
Rui Jiang, Zhongshan Li, Caiguo Zhang, Gengchao Zhang, Feng Luo, Qi Qu, Shuangqiang Tu, Zixuan Huang, Zhiyu Wang, Zheng Zhang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract For a long time, the decline in lung function has been regarded as a potential factor associated with the risk of osteoporosis (OP). Although several observational studies have investigated the relationship between lung function and OP, thei
Externí odkaz:
https://doaj.org/article/f52bd2b94f7e4e709ab069d3fb3e2ab8
Autor:
Melanie A. Blevins, Caiguo Zhang, Lingdi Zhang, Hong Li, Xueni Li, David A. Norris, Mingxia Huang, Rui Zhao
Publikováno v:
Molecular Oncology, Vol 12, Iss 8, Pp 1358-1373 (2018)
The carboxyl‐terminal binding proteins (CtBP) are transcriptional corepressors that regulate the expression of multiple epithelial‐specific and pro‐apoptotic genes. Overexpression of CtBP occurs in many human cancers where they promote the epit
Externí odkaz:
https://doaj.org/article/8ebfda7cc4454075a086e84a3cd9e2d4
Publikováno v:
Molecular Oncology, Vol 12, Iss 4, Pp 476-494 (2018)
Cullin 4B, a member of the Cullins, which serve as scaffolds to facilitate the assembly of E3 ligase complexes, is aberrantly expressed in many cancers, including osteosarcoma. Recently, we observed that CUL4B forms the CRL4BDCAF11 E3 ligase, which s
Externí odkaz:
https://doaj.org/article/92029e74250548119a790ca1438f03c4
Autor:
Zhi Chen, Wei Zhang, Kaibiao Jiang, Bin Chen, Kun Wang, Lifeng Lao, Canglong Hou, Fei Wang, Caiguo Zhang, Hongxing Shen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 10, Iss , Pp 254-268 (2018)
Cullins, critical members of the cullin-RING ubiquitin ligases (CRLs), are often aberrantly expressed in different cancers. However, the underlying mechanisms regarding aberrant expression of these cullins and the specific substrates of CRLs in diffe
Externí odkaz:
https://doaj.org/article/e09048e335f9459bab3d7ece8b71b9ab
Autor:
Zhi Chen, Kun Wang, Canglong Hou, Kaibiao Jiang, Bin Chen, Jianwei Chen, Lifeng Lao, Lie Qian, Guibin Zhong, Zude Liu, Caiguo Zhang, Hongxing Shen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Cell cycle progression in mammals is strictly controlled by a number of cyclin-dependent kinases (CDKs) and CDK inhibitors (CKIs), the expression of which is often dysregulated in cancer cells. Our previous work revealed that Cullin 4B (CUL4
Externí odkaz:
https://doaj.org/article/bf6e843c9d47433a8fe3986e9567ad83
Publikováno v:
J Vis Exp
An ongoing clinical trial, Autoimmunity Screening for Kids (ASK), is the first screening study in the general population for type 1 diabetes (T1D) and celiac disease in the United States. With the coronavirus disease 2019 (COVID-19) pandemic, the epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92422bb4ed71d5e4308880245061b038
https://doi.org/10.3791/63787
https://doi.org/10.3791/63787
Publikováno v:
Diabetes. 71
Background: Insulinoma antigen-2 (IA2) is a major self-antigen in T1D with post translational modification (PTM) of the extracellular domain (IA2ec) by deamidation eliciting T cell responses in T1D patients. Yet the autoantibodies (Abs) to these IA2e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd80a51304980bbc3b3b6e5ae521bcfa
https://doi.org/10.2337/db22-186-or
https://doi.org/10.2337/db22-186-or
Autor:
Gangwen Han, David A. Norris, Caiguo Zhang, Hong Li, Whitney A. High, Chunxia Yang, Xiao-Jing Wang, Bin Fan, Rui Zhao, Mingxia Huang, Melanie A. Blevins, Hui Deng, Mayumi Fujita, Li Bian
Publikováno v:
The Journal of investigative dermatology, vol 142, iss 2
J Invest Dermatol
J Invest Dermatol
Psoriasis is a chronic immune-mediated disease characterized by excessive proliferation of epidermal keratinocytes and increased immune cell infiltration to the skin. Although it is well-known that psoriasis pathogenesis is driven by aberrant product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff7ffab353e7a4ae5aec9eaa705ece0
https://escholarship.org/uc/item/2wk8286h
https://escholarship.org/uc/item/2wk8286h
Publikováno v:
The Journal of Pathology. 248:464-475
Inflammation is well known as an important driver of the initiation of colitis-associated cancer (CAC). Some cytokines, such as IL-6 and TNF-α can activate expression of the oncogene c-Myc (MYC) and regulate its downstream effects. Cullin-RING E3 Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e0fb0879f3e16309a7b534e1487b7ee
https://doi.org/10.1002/path.5273
https://doi.org/10.1002/path.5273
Autor:
David A. Norris, Lingdi Zhang, Caiguo Zhang, Rui Zhao, Xueni Li, Mingxia Huang, Hong Li, Melanie A. Blevins
Publikováno v:
Molecular Oncology, Vol 12, Iss 8, Pp 1358-1373 (2018)
Molecular Oncology
Molecular Oncology
The carboxyl-terminal binding proteins (CtBP) are transcriptional corepressors that regulate the expression of multiple epithelial-specific and pro-apoptotic genes. Overexpression of CtBP occurs in many human cancers where they promote the epithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cf1a5bff14b7dae9288ae61e044488
https://doi.org/10.1002/1878-0261.12330
https://doi.org/10.1002/1878-0261.12330