Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Caifeng Deng"'
Publikováno v:
Clinical and Experimental Obstetrics & Gynecology, Vol 50, Iss 9, p 195 (2023)
Background: To investigate the diagnostic value of serum transthyretin (TTR), placental protein 13 (PP13) and placental growth factor (PLGF) in preeclampsia patients. Methods: Sixty cases of pregnant women with preeclampsia who were examined in our h
Externí odkaz:
https://doaj.org/article/e2aa28ae2f3041c1a4a21ac485d92adf
Autor:
Caifeng Deng, Quan Zhang, Penghui He, Bin Zhou, Ke He, Xun Sun, Guanghua Lei, Tao Gong, Zhirong Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Celastrol might be useful in treating rheumatoid arthritis in part by inhibiting apoptosis of macrophages; however, systemic toxicity is a concern. Here the authors design celastrol-loaded nanoparticles that release a payload in response to MMP9 clea
Externí odkaz:
https://doaj.org/article/789254a8cab5414ba75cd8f2bd03c3f8
Autor:
Hongyu Jin, Yuanheng Yang, Guanghua Lei, Chao Zeng, Ke He, Yilun Wang, Caifeng Deng, Jie Wei, Xiaoxiao Li, Hui Li
Publikováno v:
CARTILAGE. 14:86-93
Objective Although most frequently used in experimental osteoarthritis (OA) pain induction, intra-articular mono-iodoacetate (MIA) injection lacks concluded references for dose selection and timing of intervention. Herein, we aimed to compare the pai
Autor:
Caifeng Deng, Xuan Zhao, Yuxiao Chen, Kelong Ai, Yuqing Zhang, Tao Gong, Chao Zeng, Guanghua Lei
Publikováno v:
ACS Nano. 16:18430-18447
Synovial fibroblasts in rheumatoid arthritis (RA) joints mediate synovial hyperplasia, progressive joint destruction, and the potential spread of disease between joints by producing multiple pathogenic proteins. Here, we deliver all-trans retinoic ac
Autor:
Caifeng Deng, Yuxiao Chen, Xuan Zhao, Liukang Yu, Yongbing Xiao, Hui Li, Yuqing Zhang, Kelong Ai, Dongfang Zhou, Xiaochun Bai, Tao Gong, Jie Wei, Chao Zeng, Guanghua Lei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31b167b1c04debe638726a467acee4d0
https://doi.org/10.2139/ssrn.4349186
https://doi.org/10.2139/ssrn.4349186
Publikováno v:
Nanomedicine. 14:2169-2187
Aim: We aimed to construct human serum albumin-Kolliphor® HS 15 nanoparticles (HSA-HS15 NPs) to overcome the limitations in targeted therapy for rheumatoid arthritis (RA) and enhance the safety of drug-loaded HSA NPs. Methodology: Celastrol (CLT)-lo
Autor:
Zhirong Zhang, Bin Zhou, Xun Sun, Guanghua Lei, Quan Zhang, Caifeng Deng, Tao Gong, Ke He, Penghui He
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Insufficient apoptosis of inflammatory macrophages and osteoclasts (OCs) in rheumatoid arthritis (RA) joints contributes toward the persistent progression of joint inflammation and destruction. Here, we deliver celastrol (CEL) to selectively induce a
Autor:
Caifeng Deng, Pei Zhang, Zhirong Zhang, Tao Gong, Ting Gong, Yuan Huang, Haohuan Li, Tiantian Tan
Publikováno v:
Biomaterials. 258
Palmitic acid-modified bovine serum albumin (PAB) was synthetized and found to own remarkable scavenger receptor-A (SR-A) targeting ability in vitro and in vivo, through which activated macrophages took up PAB nanoparticles (PAB NPs) 9.10 times more
Publikováno v:
Journal of Materials Chemistry B. 6:3163-3180
The safe and efficient targeted delivery of chemotherapeutic drugs has remained a challenge in metastatic breast cancer therapy. Herein, we report a rational drug delivery strategy of co-administering tumor-penetrating peptide-iRGD with self-assemble
Publikováno v:
Nanomedicine (London, England). 14(16)