Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Caicai Zhu"'
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Irritable bowel syndrome (IBS) is common and difficult to treat and its pathogenesis is closely related to gut microbiota. However, differences in gut microbiota of patients in different regions make it more difficult to elucidate
Externí odkaz:
https://doaj.org/article/251a9dd917e945739ca49310d3b59307
Publikováno v:
BMC Gastroenterology
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-12 (2021)
Background Irritable bowel syndrome (IBS) is common and difficult to treat and its pathogenesis is closely related to gut microbiota. However, differences in gut microbiota of patients in different regions make it more difficult to elucidate the mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13804f881ba5048f0c5e945e80842bc
http://europepmc.org/articles/PMC7934555
http://europepmc.org/articles/PMC7934555
Autor:
Maureen Beresini, Vickie Tsui, John S. Wai, F. Anthony Romero, Gladys de Leon Boenig, Patrick Cyr, Xiaoyu Zhu, Kevin X. Chen, Jiangpeng Liao, Edna F. Choo, Susan Kaufman, Fei Wang, Kwong Wah Lai, Caicai Zhu, Zhongguo Chen, Terry Crawford, Weichao Shen, Wenfeng Liu, Jeremy Murray, Yingjie Li, Sarah M. Bronner, Steven Magnuson, Justin Ly
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:15-23
A novel, potent, and orally bioavailable inhibitor of the bromodomain of CBP, compound 35 (GNE-207), has been identified through SAR investigations focused on optimizing al bicyclic heteroarene to replace the aniline present in the published GNE-272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a093625fe16457098a0a0b8d624a6c4e
https://doi.org/10.1016/j.bmcl.2017.11.025
https://doi.org/10.1016/j.bmcl.2017.11.025