Bifunctional small molecules that mediate the degradation of extracellular proteins.

Autor: Caianiello DF; Department of Chemistry, Yale University, New Haven, CT, USA., Zhang M; Department of Chemistry, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA., Ray JD; Department of Chemistry, Yale University, New Haven, CT, USA., Howell RA; Department of Chemistry, Yale University, New Haven, CT, USA., Swartzel JC; Department of Chemistry, Yale University, New Haven, CT, USA.; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT, USA., Branham EMJ; Department of Chemistry, Yale University, New Haven, CT, USA., Chirkin E; Department of Chemistry, Yale University, New Haven, CT, USA., Sabbasani VR; Department of Chemistry, Yale University, New Haven, CT, USA., Gong AZ; Department of Chemistry, Yale University, New Haven, CT, USA., McDonald DM; Department of Chemistry, Yale University, New Haven, CT, USA., Muthusamy V; Yale Center for Precision Cancer Modeling, Yale University School of Medicine, New Haven, CT, USA., Spiegel DA; Department of Chemistry, Yale University, New Haven, CT, USA. david.spiegel@yale.edu.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2021 Sep; Vol. 17 (9), pp. 947-953. Date of Electronic Publication: 2021 Aug 19.