Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Caian L Vinhaes"'
Autor:
Caian L Vinhaes, Thomas A Carmo, Artur T L Queiroz, Kiyoshi F Fukutani, Mariana Araújo-Pereira, María B Arriaga, Marcus V G Lacerda, Manoel Barral-Netto, Bruno B Andrade
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009886 (2021)
Homeostatic perturbation caused by infection fosters two major defense strategies, resistance and tolerance, which promote the host's survival. Resistance relates to the ability of the host to restrict the pathogen load. Tolerance minimizes collatera
Externí odkaz:
https://doaj.org/article/b05dcac71d594064bdbb3ddd522c3c12
Autor:
Juan M Cubillos-Angulo, Caian L Vinhaes, Eduardo R Fukutani, Victor V S Albuquerque, Artur T L Queiroz, Bruno B Andrade, Kiyoshi F Fukutani
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239061 (2020)
Diabetes (DM) has a significant impact on public health. We performed an in silico study of paired datasets of messenger RNA (mRNA) micro-RNA (miRNA) transcripts to delineate potential biosignatures that could distinguish prediabetes (pre-DM), type-1
Externí odkaz:
https://doaj.org/article/2cc8143e6ad74111b4ec88041df6ae36
Autor:
Moreno M. S. Rodrigues, Beatriz Barreto-Duarte, Caian L. Vinhaes, Mariana Araújo-Pereira, Eduardo R. Fukutani, Keityane Bone Bergamaschi, Afrânio Kristki, Marcelo Cordeiro-Santos, Valeria C. Rolla, Timothy R. Sterling, Artur T. L. Queiroz, Bruno B. Andrade
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Identifying patients at increased risk of loss to follow-up (LTFU) is key to developing strategies to optimize the clinical management of tuberculosis (TB). The use of national registry data in prediction models may be a useful to
Externí odkaz:
https://doaj.org/article/107ecd0c16c04eed964350da523ab35a
Autor:
Beatriz B. S. Passos, Mariana Araújo-Pereira, Caian L. Vinhaes, Eduardo P. Amaral, Bruno B. Andrade
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Despite major global efforts to eliminate tuberculosis, which is caused by Mycobacterium tuberculosis (Mtb), this disease remains as a major plague of humanity. Several factors associated with the host and Mtb interaction favor the infection establis
Externí odkaz:
https://doaj.org/article/6543f0be09444fa68bfa19fe64201459
Autor:
Caian L. Vinhaes, Eduardo R. Fukutani, Gabriel C. Santana, María B. Arriaga, Beatriz Barreto-Duarte, Mariana Araújo-Pereira, Mateus Maggiti-Bezerril, Alice M.S. Andrade, Marina C. Figueiredo, Ginger L. Milne, Valeria C. Rolla, Afrânio L. Kristki, Marcelo Cordeiro-Santos, Timothy R. Sterling, Bruno B. Andrade, Artur T.L. Queiroz
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109135- (2024)
Summary: Tuberculosis-diabetes mellitus (TB-DM) is linked to a distinct inflammatory profile, which can be assessed using multi-omics analyses. Here, a machine learning algorithm was applied to multi-platform data, including cytokines and gene expres
Externí odkaz:
https://doaj.org/article/5f21262bf6024bae9b93b8627b42b9d7
Autor:
Artur T. L. Queiroz, Caian L. Vinhaes, Eduardo R. Fukutani, Akshay N. Gupte, Nathella Pavan Kumar, Kiyoshi F. Fukutani, María B. Arriaga, Timothy R. Sterling, Subash Babu, Sanjay Gaikwad, Rajesh Karyakarte, Vidya Mave, Mandar Paradhkar, Vijay Viswanathan, Amita Gupta, Bruno B. Andrade, Hardy Kornfeld, the RePORT Brazil, RePORT India Consortia
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Diabetes mellitus (DM) increases tuberculosis (TB) severity. We compared blood gene expression in adults with pulmonary TB, with or without diabetes mellitus (DM) from sites in Brazil and India. RNA sequencing (RNAseq) performed at baseline
Externí odkaz:
https://doaj.org/article/62e9c8fb3cdf4d7fb78f39d5f826c7bf
Autor:
Caian L. Vinhaes, Eduardo R. Fukutani, Mariana Araujo-Pereira, Artur T.L. Queiroz, Bruno B. Andrade
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 27, Iss , Pp 103642- (2023)
Introdução: A tuberculose (TB) é uma das principais causas de morte no mundo, e o Diabetes Mellitus (DM) é uma das principais comorbidades associadas à doença. O DM afeta a resposta inflamatória crônica associada à TB, aumentando o risco de
Externí odkaz:
https://doaj.org/article/c6873fcbf86442138cd2494712bdc976
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 27, Iss , Pp 103670- (2023)
Introdução: A tuberculose (TB) permanece classificada entre as principais causas de morte no mundo devido a um único agente infeccioso. O diabetes mellitus (DM) pode afetar a ativação imune e tem sido associado a um risco aumentado de TB ativa e
Externí odkaz:
https://doaj.org/article/43a0e069a1e440279056010a7518bde6
Autor:
Mariana Araújo-Pereira, Charlotte Schutz, Beatriz Barreto-Duarte, David Barr, Klauss Villalva-Serra, Caian L. Vinhaes, Amy Ward, Graeme Meintjes, Bruno B. Andrade
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAnemia frequently affects people living with HIV (PLHIV). Nevertheless, the impact of anemia on treatment outcomes of patients with HIV-associated tuberculosis (TB) and the underlying molecular profiles are not fully characterized. The ai
Externí odkaz:
https://doaj.org/article/4af170559d074d9cab7b316ca501ff14
Autor:
Gopalan Narendran, Keerthana Jyotheeswaran, Thirumaran Senguttuvan, Caian L. Vinhaes, Ramesh K. Santhanakrishnan, Tamizhselvan Manoharan, Anbhalagan Selvaraj, Padmapriyadarsini Chandrasekaran, Pradeep A. Menon, Kannabiran P. Bhavani, Devarajulu Reddy, Ravichandran Narayanan, Balaji Subramanyam, Sekhar Sathyavelu, Raja Krishnaraja, Pownraj Kalirajan, Dhanalakshmi Angamuthu, Stella Mary Susaimuthu, Ranjit R.K. Ganesan, Srikanth P. Tripathy, Soumya Swaminathan, Bruno B. Andrade
Publikováno v:
International Journal of Infectious Diseases, Vol 98, Iss , Pp 261-267 (2020)
Objective: The influence of tuberculosis (TB)-immune reconstitution inflammatory syndrome (IRIS) on TB treatment outcomes and its risk factors were investigated among people with human immunodeficiency virus (HIV) and co-infected with TB. Methods: Ne
Externí odkaz:
https://doaj.org/article/061d764453a448af9209c1040bd14fc3