Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Cai-Xia Peng"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 117:47-51
Synaptic communication forms the basis of learning and memory. Disruptions of synaptic function and memory have been widely reported in many neurological diseases, such as dementia. Thus, restoration of impaired synaptic communication is a potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6d59ee46dd116b702d5367706c75b8
https://doi.org/10.1016/j.pbb.2013.12.006
https://doi.org/10.1016/j.pbb.2013.12.006
Autor:
Xin Zhou, Juan Hu, Gao-Shang Chai, Jia-Yu Zhang, Cai-Xia Peng, Xiu-Qing Yao, Xinghua Liu, Jian-Zhi Wang, Gong-Ping Liu, Wei Wei, Qun Wang, Hai-Rong Shi, Xia-Chun Li
Publikováno v:
Molecular Therapy. 21(12):2247-2257
Deficits of protein phosphatase-2A (PP2A) play a crucial role in tau hyperphosphorylation, amyloid overproduction, and synaptic suppression of Alzheimer's disease (AD), in which PP2A is inactivated by the endogenously increased inhibitory protein, na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0142defe64e1f1fb67caec20eea6b3
Autor:
Ying-Hua Liu, Yao Zhang, Fu-Yuan Cao, Qing Tian, Jian-Zhi Wang, Wei Wei, Cai-Xia Peng, Xiu-Qing Yao, Qun Wang, Xiao-Ping Hong
Publikováno v:
Hippocampus. 20:1339-1349
An increased hippocampal neurogenesis has been observed in Alzheimer disease (AD), the most common neurodegenerative disorder characterized with accumulation of β-amyloid (Aβ) and hyperphosphorylated tau (p-tau). Studies in transgenic mouse models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15536d7f6a9aa288cc3316f127780719
https://doi.org/10.1002/hipo.20712
https://doi.org/10.1002/hipo.20712
Publikováno v:
The Journal of Neuroscience. 30:3839-3848
Protein phosphatase 2A (PP2A) is indispensable in development, and deficits of PP2A and deterioration of neuronal axons have been observed in several neurodegenerative disorders, but the direct link between PP2A and the neuronal axon development is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928e018050796927ef42a95fade8f96f
https://doi.org/10.1523/jneurosci.5174-09.2010
https://doi.org/10.1523/jneurosci.5174-09.2010
Publikováno v:
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. 33(3)
This study investigated the effects of benazepril administered in the morning or evening on the diurnal variation of renin-angiotensin-aldosterone system (RAAS) and clock genes in the kidney. The male Wistar rat models of 5/6 subtotal nephrectomy (ST
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e83f1a6400b663f2355059c61715c4b
https://pubmed.ncbi.nlm.nih.gov/23771662
https://pubmed.ncbi.nlm.nih.gov/23771662
Publikováno v:
Neurobiology of aging. 34(6)
The current therapies for Alzheimer's disease (AD) are merely palliative that cannot arrest the pathologic progression of the disease. Therefore, it is critical to develop treatments that can target the disease-modifying molecule(s). In the present s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16976e6bf8828ed5bce1ac572e318f6
https://pubmed.ncbi.nlm.nih.gov/23402899
https://pubmed.ncbi.nlm.nih.gov/23402899
Autor:
Jian-Zhi Wang, Cai-Xia Peng, Wei Wei, Ying-Hua Liu, Fu-Yuan Cao, Qun Wang, Xiao-Ping Hong, Qing Tian
Publikováno v:
Neurochemical research. 36(2)
Altered neurogenesis has been reported in Alzheimer disease (AD), the most common neurodegenerative disorder characterized with hyperphosphorylated tau and accumulation of β-amyloid (Aβ). Recent studies suggest that tau phosphorylation is essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cd67ac33aadf444ba210fa37913a55
https://pubmed.ncbi.nlm.nih.gov/21061060
https://pubmed.ncbi.nlm.nih.gov/21061060
Publikováno v:
Alzheimer's & Dementia. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06d0e5f2a64a89eb85a517bb7558ffb3
https://doi.org/10.1016/j.jalz.2010.05.1383
https://doi.org/10.1016/j.jalz.2010.05.1383
Autor:
Cai-Xia Peng, Xin Zhou, Xiu-Qing Yao, Jun Yin, Gong-Ping Liu, Hai-Hong Shi, Juan Hu, Qun Wang, Wei Wei, Hong-Lian Li, Yao Zhang, Jian-Zhi Wang
Publikováno v:
Neurobiology of aging. 33(2)
A chronic neuron loss is the cardinal pathology in Alzheimer disease (AD), but it is still not understood why most neurons in AD brain do not accomplish apoptosis even though they are actually exposed to an environment with enriched proapoptotic fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140f108adaad8f202b2a022584c560fa
https://pubmed.ncbi.nlm.nih.gov/20138402
https://pubmed.ncbi.nlm.nih.gov/20138402
Publikováno v:
Alzheimer's & Dementia. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93faa2929e1ffd3ba47a6baeb0aa50bc
https://doi.org/10.1016/j.jalz.2009.04.809
https://doi.org/10.1016/j.jalz.2009.04.809