Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Cai-Hong Yun"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Chitin is one of the most abundant natural biopolymers and serves as a critical structural component of extracellular matrices, including fungal cell walls and insect exoskeletons. As a linear polymer of β-(1,4)-linked N-acetylglucosamine,
Externí odkaz:
https://doaj.org/article/cac70199615349cc865eb45037634e28
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Once DNA breaks occur, poly(ADP-ribose) polymerase 1 (PARP1) ADP-ribosylates itself and other DNA repair factors to initiate the repair process. Here, the authors resolve the crystal structures of mouse and human HPF1, and human HPF1/PARP1 complex pr
Externí odkaz:
https://doaj.org/article/5521b4d0d2ee4c4d8454f7128bbf8047
Autor:
Yue Lu, Zhenzhen Fan, Su‐Jie Zhu, Xiaoxing Huang, Zhongji Zhuang, Yunzhan Li, Zhou Deng, Lei Gao, Xuehui Hong, Ting Zhang, Li Li, Xihuan Sun, Wei Huang, Jingfang Zhang, Yan Liu, Baoding Zhang, Jie Jiang, Fu Gui, Zheng Wang, Qiyuan Li, Siyang Song, Xin Huang, Qiao Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Cai‐Hong Yun, Liang Chen, Xianming Deng
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 1, Pp n/a-n/a (2022)
Abstract More than 60% of nonsmall cell lung cancer (NSCLC) patients show a positive response to the first ALK inhibitor, crizotinib, which has been used as the standard treatment for newly diagnosed patients with ALK rearrangement. However, most pat
Externí odkaz:
https://doaj.org/article/c6601c62cfee423f8b9920da0e450eea
Autor:
Daqi Tu, Zehua Zhu, Alicia Y. Zhou, Cai-hong Yun, Kyung-Eun Lee, Angela V. Toms, Yiqun Li, Gavin P. Dunn, Edmond Chan, Tran Thai, Shenghong Yang, Scott B. Ficarro, Jarrod A. Marto, Hyesung Jeon, William C. Hahn, David A. Barbie, Michael J. Eck
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 747-758 (2013)
Upon stimulation by pathogen-associated inflammatory signals, TANK-binding kinase 1 (TBK1) induces type I interferon expression and modulates nuclear factor κB (NF-κB) signaling. Here, we describe the 2.4 Å-resolution crystal structure of nearly f
Externí odkaz:
https://doaj.org/article/994a8e3a594e4cb5822df3147232d8d4
Autor:
Kevin G. Hicks, Ahmad A. Cluntun, Heidi L. Schubert, Sean R. Hackett, Jordan A. Berg, Paul G. Leonard, Mariana A. Ajalla Aleixo, Youjia Zhou, Alex J. Bott, Sonia R. Salvatore, Fei Chang, Aubrie Blevins, Paige Barta, Samantha Tilley, Aaron Leifer, Andrea Guzman, Ajak Arok, Sarah Fogarty, Jacob M. Winter, Hee-Chul Ahn, Karen N. Allen, Samuel Block, Iara A. Cardoso, Jianping Ding, Ingrid Dreveny, William C. Gasper, Quinn Ho, Atsushi Matsuura, Michael J. Palladino, Sabin Prajapati, Pengkai Sun, Kai Tittmann, Dean R. Tolan, Judith Unterlass, Andrew P. VanDemark, Matthew G. Vander Heiden, Bradley A. Webb, Cai-Hong Yun, Pengkai Zhao, Bei Wang, Francisco J. Schopfer, Christopher P. Hill, Maria Cristina Nonato, Florian L. Muller, James E. Cox, Jared Rutter
Publikováno v:
Science
Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry int
Publikováno v:
International Journal of Biological Macromolecules. 219:500-507
The PA28 family proteasome activators play important roles in regulating proteasome activities. Though the three paralogs (PA28α, PA28β, and PA28γ) are similar in terms of primary sequence, they show significant differences in expression pattern,
Autor:
Pasi A. Jänne, Nathanael S. Gray, Michael J. Eck, Ting Xie, Marzia Capelletti, Cai-Hong Yun, Hwan Geun Choi, Dalia Ercan
Supplemental Figures 1 - 7. Figure S1. Sequence tracings from WZ4002 resistant Ba/F3 cells demonstrating EGFR L718Q, C797S and L844V mutations. Figure S2. EGFR Del19 Ba/F3 cells alone or expressing EGFR L718Q were treated with EGF. Figure S3. Structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254b39ed3293d108b463112f0e8a05b7
https://doi.org/10.1158/1078-0432.22456683.v1
https://doi.org/10.1158/1078-0432.22456683.v1
Autor:
Geoffrey R. Oxnard, Marc Ladanyi, Pasi A. Jänne, Michael J. Eck, Mark G. Kris, Binsheng Zhao, Michelle S. Ginsberg, Vincent A. Miller, Maria E. Arcila, Cai-Hong Yun, Khedoudja Nafa, Marzia Capelletti, Mai He
CCR Translation for This Article from EGFR Exon 19 Insertions: A New Family of Sensitizing EGFR Mutations in Lung Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17650414be9f16a6de067dd849984411
https://doi.org/10.1158/1078-0432.22445919.v1
https://doi.org/10.1158/1078-0432.22445919.v1
Autor:
Geoffrey R. Oxnard, Marc Ladanyi, Pasi A. Jänne, Michael J. Eck, Mark G. Kris, Binsheng Zhao, Michelle S. Ginsberg, Vincent A. Miller, Maria E. Arcila, Cai-Hong Yun, Khedoudja Nafa, Marzia Capelletti, Mai He
PDF file - 79K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7342edbb9824b3711bb8972b843b49
https://doi.org/10.1158/1078-0432.22445916.v1
https://doi.org/10.1158/1078-0432.22445916.v1
Autor:
Pasi A. Jänne, Nathanael S. Gray, Michael J. Eck, Ting Xie, Marzia Capelletti, Cai-Hong Yun, Hwan Geun Choi, Dalia Ercan
Supplemental Figure legends. This file contains the detailed descriptions of the supplementaal figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640b282241a04eed44532379926959b5
https://doi.org/10.1158/1078-0432.22456686.v1
https://doi.org/10.1158/1078-0432.22456686.v1