Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Cai M, Roberts"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17539 (2023)
TWIST1 is a transcription factor that is necessary for healthy neural crest migration, mesoderm development, and gastrulation. It functions as a key regulator of epithelial-to-mesenchymal transition (EMT), a process by which cells lose their polarity
Externí odkaz:
https://doaj.org/article/9c2905c5b2f541d0b502b314280b6f00
Epithelial ovarian cancer (EOC) remains the most lethal gynecologic malignancy, largely due to metastasis and drug resistant recurrences. Fifteen percent of ovarian tumors carry mutations in BRCA1 or BRCA2, rendering them vulnerable to treatment with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c63a56d5ae7e711d80ba34df9ce6bf67
https://doi.org/10.20944/preprints202304.0327.v1
https://doi.org/10.20944/preprints202304.0327.v1
Autor:
Gil Mor, Carlotta A. Glackin, Ayesha B. Alvero, Natalia J. Sumi, Marta Gurea, Carlos Cardenas, Jamie Goodner-Bingham, Cai M. Roberts, Roslyn Tedja, Yang Yang-Hartwich
The effects of Î"b-Twist1 overexpression on spheroids formation and migration. (A) Representative images of spheroid forming assay. (B) Representative images of the migrated cells in migration assay. (C) Quantification of the migrated cells.*P< 0.05
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1cfd089c710e00c75062ac93bccd47b
https://doi.org/10.1158/1541-7786.22515375.v1
https://doi.org/10.1158/1541-7786.22515375.v1
Autor:
Gil Mor, Carlotta A. Glackin, Ayesha B. Alvero, Natalia J. Sumi, Marta Gurea, Carlos Cardenas, Jamie Goodner-Bingham, Cai M. Roberts, Roslyn Tedja, Yang Yang-Hartwich
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d8b0bd8df52e389da5fae0cc5de2f4
https://doi.org/10.1158/1541-7786.22515372.v1
https://doi.org/10.1158/1541-7786.22515372.v1
Autor:
Gil Mor, Carlotta A. Glackin, Ayesha B. Alvero, Natalia J. Sumi, Marta Gurea, Carlos Cardenas, Jamie Goodner-Bingham, Cai M. Roberts, Roslyn Tedja, Yang Yang-Hartwich
The protein levels of Twist1 (A) and p53 (B) in tumor samples. Protein levels were determined by the quantification of western blot band intensity comparing to GAPDH bands as loading control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ba79d2bebe0c92472184e1b6d7b375
https://doi.org/10.1158/1541-7786.22515390.v1
https://doi.org/10.1158/1541-7786.22515390.v1
Autor:
Gil Mor, Carlotta A. Glackin, Ayesha B. Alvero, Natalia J. Sumi, Marta Gurea, Carlos Cardenas, Jamie Goodner-Bingham, Cai M. Roberts, Roslyn Tedja, Yang Yang-Hartwich
Expression of p53-associated E3 ligase in cancer cell lines. (A) RNA expression of MDM2, Pirh2, and E6-AP1, and TOPORS assessed by QPCR in R182 (p53high/Twist-) and Tara R182 (p53low/Twist+) cells. GADPH was used as reference gene. (B) Protein expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5420ebcaee1870a597274c0ae907f56
https://doi.org/10.1158/1541-7786.22515381.v1
https://doi.org/10.1158/1541-7786.22515381.v1
Autor:
Gil Mor, Carlotta A. Glackin, Ayesha B. Alvero, Natalia J. Sumi, Marta Gurea, Carlos Cardenas, Jamie Goodner-Bingham, Cai M. Roberts, Roslyn Tedja, Yang Yang-Hartwich
TP53 mutation status and protein levels of p53 and Twist1 ovarian cancer cell lines. * u = unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0322230e2c9493764fb07517c04225
https://doi.org/10.1158/1541-7786.22515387
https://doi.org/10.1158/1541-7786.22515387
CBX7 binds the E-box to inhibit TWIST-1 function and inhibit tumorigenicity and metastatic potential
Autor:
Ayesha B. Alvero, Qing Xiao, Roslyn Tedja, Sai Zhang, Gang Yin, Yaqi Gan, Xiaoying Wu, Sudhakar V. Nuti, Mary Pitruzzello, Juanni Li, Yimin Li, Cai M. Roberts, Gil Mor
Publikováno v:
Oncogene
Deaths from ovarian cancer usually occur when patients succumb to overwhelmingly numerous and widespread micrometastasis. Whereas epithelial-mesenchymal transition is required for epithelial ovarian cancer cells to acquire metastatic potential, the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08459b520d999047c7fdb118382254a
https://doi.org/10.1038/s41388-020-1269-5
https://doi.org/10.1038/s41388-020-1269-5
Autor:
Wei Wen, Gina Lowe, Cai M. Roberts, James Finlay, Ernest S. Han, Carlotta A. Glackin, Thanh Hue Dellinger
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1983 (2018)
A growing body of evidence has demonstrated the promising anti-tumor effects of resveratrol in ovarian cancer cells, including its inhibitory effects on STAT3 activation. Nonetheless, the low bioavailability of resveratrol has reduced its attractiven
Externí odkaz:
https://doaj.org/article/81e2aa0fe24748f0904e8ec587f22a00
Autor:
Yuan You, Hong Liu, Gil Mor, Anthony Maxwell, Jiwon Jeong, Brett D. Lindenbach, Demetrios T. Braddock, Jiahui Ding, Paulomi Aldo, Xuemin Qiu, Paul R. Stabach, Cai M. Roberts, Ai-Hua Liao
Publikováno v:
EMBO Rep
Zika virus is a positive-sense single-stranded RNA virus, which can be transmitted across the placenta and has adverse effects on fetal development during pregnancy. The severity of these complications highlights the importance of prevention and trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0dba0c84b2253c402bd3547f908d0f1
https://doi.org/10.15252/embr.202152450
https://doi.org/10.15252/embr.202152450