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Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction.

Autor: Wang XX; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Zhao YM; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Zhang QY; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Zhao JX; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Yin DH; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Zhang ZZ; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Jin XY; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China., Li SN; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China., Ji HY; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Chen HY; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Guo XF; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Yu Y; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Ma WY; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Yan H; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China., Li H; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Ou-Yang QM; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China., Pan ZW; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China., Liang HH; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China., Wang N; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China. wangning@ems.hrbmu.edu.cn., Chen W; Department of Cardiovascular Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150086, China. cw19820120@163.com., Cai BZ; Department of Pharmacy at the Second Affiliated Hospital, and Department of Pharmacology at College of Pharmacy (National Key Laboratory of Frigid Zone Cardiovascular Diseases, Key Laboratory of Cardiovascular Research, Ministry of Education), Harbin Medical University, Harbin, 150086, China. caibz@ems.hrbmu.edu.cn.; Institute of Clinical Pharmacology (The Heilongjiang Key Laboratory of Drug Research), Harbin Medical University, Harbin, 150086, China. caibz@ems.hrbmu.edu.cn.; NHC Key Laboratory of Cell Transplantation, The Heilongjiang Key Laboratory of Drug Research, Harbin Medical University, Harbin, 150001, China. caibz@ems.hrbmu.edu.cn., Liu Y; Department of Clinical Laboratory at the Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, China. rainfall1982@163.com.

Publikováno v: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2024 Jul; Vol. 45 (7), pp. 1425-1437. Date of Electronic Publication: 2024 Jun 05.

Crosstalk between PML and p53 in response to TGF-β1: A new mechanism of cardiac fibroblast activation.

Autor: Huang D; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhao D; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li M; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Chang SY; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Xue YD; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Xu N; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li SJ; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Tang NN; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Gong LL; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Liu YN; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Yu H; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li QS; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li PY; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Liu JL; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Chen HX; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Liu MB; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhang WY; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhao XM; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Lang XZ; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li ZD; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Liu Y; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Ma ZY; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li JM; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Wang N; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Tian H; Department of Cardiovascular Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China.; Future Medical laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150081, China., Cai BZ; Department of Pharmacy at the Second Affiliated Hospital, Department of Pharmacology at College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China.

Publikováno v: International journal of biological sciences [Int J Biol Sci] 2023 Jan 22; Vol. 19 (3), pp. 994-1006. Date of Electronic Publication: 2023 Jan 22 (Print Publication: 2023).