Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer

Autor: de Miguel, Fernando J., Gentile, Claudia, Feng, William W., Silva, Shannon J., Sankar, Akshay, Exposito, Francisco, Cai, Wesley L., Melnick, Mary Ann, Robles-Oteiza, Camila, Hinkley, Madeline M., Tsai, Jeanelle A., Hartley, Antja-Voy, Wei, Jin, Wurtz, Anna, Li, Fangyong, Toki, Maria I., Rimm, David L., Homer, Robert, Wilen, Craig B., Xiao, Andrew Z., Qi, Jun, Yan, Qin, Nguyen, Don X., Jänne, Pasi A., Kadoch, Cigall, Politi, Katerina A.

Publikováno v: In Cancer Cell 14 August 2023 41(8):1516-1534

DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.

Autor: Strine, Madison S.^1,2 (AUTHOR), Cai, Wesley L.³ (AUTHOR), Wei, Jin^1,2,4 (AUTHOR), Alfajaro, Mia Madel^1,2 (AUTHOR), Filler, Renata B.^1,2 (AUTHOR), Biering, Scott B.⁵ (AUTHOR), Sarnik, Sylvia⁶ (AUTHOR), Chow, Ryan D.⁷ (AUTHOR), Patil, Ajinkya^8,9,10 (AUTHOR), Cervantes, Kasey S.^8,9 (AUTHOR), Collings, Clayton K.^8,9 (AUTHOR), DeWeirdt, Peter C.¹¹ (AUTHOR), Hanna, Ruth E.¹¹ (AUTHOR), Schofield, Kevin¹² (AUTHOR), Hulme, Christopher^12,13 (AUTHOR), Konermann, Silvana^14,15 (AUTHOR), Doench, John G.¹¹ (AUTHOR), Hsu, Patrick D.^15,16,17,18 (AUTHOR), Kadoch, Cigall^7,8,19 (AUTHOR), Yan, Qin^20,21 (AUTHOR)

Publikováno v: PLoS Biology. 6/13/2023, Vol. 21 Issue 6, p1-29. 29p. 5 Graphs.

DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner

Autor: Strine, Madison S, Cai, Wesley L, Wei, Jin, Alfajaro, Mia Madel, Filler, Renata B, Biering, Scott B, Sarnik, Sylvia, Chow, Ryan D, Patil, Ajinkya, Cervantes, Kasey S, Collings, Clayton K, DeWeirdt, Peter C, Hanna, Ruth E, Schofield, Kevin, Hulme, Christopher, Konermann, Silvana, Doench, John G, Hsu, Patrick D, Kadoch, Cigall, Yan, Qin, Wilen, Craig B

Publikováno v: PLoS biology, vol 21, iss 6

Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding of Coronavirus Disease 2019 (COVID-19). We previously performed a genome-wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::f7980ae51fe3951bd181d796c87c0884
https://escholarship.org/uc/item/2q11m5f2

Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain.

Autor: Cai, Wesley L.¹ (AUTHOR), Greer, Celeste B.^1,2 (AUTHOR), Chen, Jocelyn F.¹ (AUTHOR), Arnal-Estapé, Anna^1,3 (AUTHOR), Cao, Jian^1,3,4 (AUTHOR), Yan, Qin^1,3,5,6 (AUTHOR) qin.yan@yale.edu, Nguyen, Don X.^1,3,5,6,7 (AUTHOR) don.nguyen@yale.edu

Publikováno v: BMC Medical Genomics. 3/6/2020, Vol. 13 Issue 1, p1-18. 18p.

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