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Raman spectroscopic deep learning with signal aggregated representations for enhanced cell phenotype and signature identification.

Autor: Lu S; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, 2279 Lishui Road, Nanshan District, Shenzhen 518055, Guangdong, P. R. China.; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, 9 Kexue Avenue, Guangming District, Shenzhen 518132, Guangdong, P. R. China., Huang Y; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, 2279 Lishui Road, Nanshan District, Shenzhen 518055, Guangdong, P. R. China., Shen WX; Bioinformatics and Drug Design Group, Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore., Cao YL; Tangyi and Tsinghua Shenzhen International Graduate School Collaborative Program, Tsinghua University, 2279 Lishui Road, Nanshan District, Shenzhen 518055, Guangdong, P. R. China., Cai M; Tangyi and Tsinghua Shenzhen International Graduate School Collaborative Program, Tsinghua University, 2279 Lishui Road, Nanshan District, Shenzhen 518055, Guangdong, P. R. China., Chen Y; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, 2279 Lishui Road, Nanshan District, Shenzhen 518055, Guangdong, P. R. China.; Shenzhen Kivita Innovative Drug Discovery Institute, Shenzhen 518057, Guangdong, P. R. China., Tan Y; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, 2279 Lishui Road, Nanshan District, Shenzhen 518055, Guangdong, P. R. China.; Institute of Drug Discovery Technology, Ningbo University, 818 Fenghua Road, Ningbo 315211, Zhejiang, P. R. China., Jiang YY; School of Pharmaceutical Sciences, Tsinghua University, 30 Shuangqing Road, Haidian District, Beijing 100084, P. R. China., Chen YZ; The State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Biology, Tsinghua Shenzhen International Graduate School, Tsinghua University, 2279 Lishui Road, Nanshan District, Shenzhen 518055, Guangdong, P. R. China.; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, 9 Kexue Avenue, Guangming District, Shenzhen 518132, Guangdong, P. R. China.

Publikováno v: PNAS nexus [PNAS Nexus] 2024 Jul 03; Vol. 3 (8), pp. pgae268. Date of Electronic Publication: 2024 Jul 03 (Print Publication: 2024).