Molecular Pharmacology of delta-Opioid Receptors

Autor: Gendron, L, Cahill, CM, von Zastrow, M, Schiller, PW, Pineyro, G

Publikováno v: Gendron, L; Cahill, CM; von Zastrow, M; Schiller, PW; & Pineyro, G. (2016). Molecular Pharmacology of delta-Opioid Receptors. PHARMACOLOGICAL REVIEWS, 68(3), 631-700. doi: 10.1124/pr.114.008979. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6z76z453

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::68309db72fa8a0b0e0f48e9eaf06e350
http://www.escholarship.org/uc/item/6z76z453

Neuropathic Pain Alters Reward and Affect via Kappa Opioid Receptor (KOR) Upregulation

Autor: Liu, S, Cook, C, Thai, E, Pickens, S, Taylor, AM, Tea, VD, Carroll, I, Leslie, FM, Evans, CJ, Cahill, CM

Publikováno v: Liu, S; Cook, C; Thai, E; Pickens, S; Taylor, AM; Tea, VD; et al.(2016). Neuropathic Pain Alters Reward and Affect via Kappa Opioid Receptor (KOR) Upregulation. FASEB JOURNAL, 30. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5zc5f6pf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::9f55babde863b8d5442a1e3ce8ca8d64
http://www.escholarship.org/uc/item/5zc5f6pf

Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408

Autor: Milne, B, Jhamandas, K, Sutak, M, Grenier, P, Cahill, CM

Publikováno v: Milne, B; Jhamandas, K; Sutak, M; Grenier, P; & Cahill, CM. (2014). Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408. European Journal of Pharmacology, 743, 89-97. doi: 10.1016/j.ejphar.2014.08.040. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6gc826m1

© 2014 Elsevier B.V. All rights reserved. Ultra-low doses of non-selective α2-adrenoceptor antagonists augment acute spinal morphine antinociception and block morphine tolerance; however, the receptor involved in mediating these effects is currentl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::0b272c7eb167323f1c5a7cb8bfddb1a2
http://www.escholarship.org/uc/item/6gc826m1

Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl-homeostasis

Autor: Ferrini, F, Trang, T, Mattioli, TAM, Laffray, S, Del'Guidice, T, Lorenzo, LE, Castonguay, A, Doyon, N, Zhang, W, Godin, AG, Mohr, D, Beggs, S, Vandal, K, Beaulieu, JM, Cahill, CM, Salter, MW, De Koninck, Y

Publikováno v: Ferrini, F; Trang, T; Mattioli, TAM; Laffray, S; Del'Guidice, T; Lorenzo, LE; et al.(2013). Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl-homeostasis. Nature Neuroscience, 16(2), 183-192. doi: 10.1038/nn.3295. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7cb5f8pv

A major unresolved issue in treating pain is the paradoxical hyperalgesia produced by the gold-standard analgesic morphine and other opiates. We found that hyperalgesia-inducing treatment with morphine resulted in downregulation of the K+-Cl-co-trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::88b5109ec96f36ddc4552e30c9ac2579
http://www.escholarship.org/uc/item/7cb5f8pv

Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis

Autor: Naeini, RS, Cahill, CM, Ribeiro-da-Silva, A, Ménard, HA, Henry, JL

Publikováno v: Naeini, RS; Cahill, CM; Ribeiro-da-Silva, A; Ménard, HA; & Henry, JL. (2005). Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis. European Journal of Neuroscience, 22(8), 2005-2015. doi: 10.1111/j.1460-9568.2005.04382.x. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/790878j7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::1f549373c8afd5e6a0039f041cd58f05
http://www.escholarship.org/uc/item/790878j7