Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Cagri A. Savran"'
Autor:
Yingwen Hu, Danyang Chen, John V. Napoleon, Madduri Srinivasarao, Sunil Singhal, Cagri A. Savran, Philip S. Low
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Retrieval of circulating tumor cells (CTC) has proven valuable for assessing a patient's cancer burden, evaluating response to therapy, and analyzing which drug might treat a cancer best. Although most isolation methods retrieve CTCs based o
Externí odkaz:
https://doaj.org/article/94820e1958bd4c72822ccd227b145a1c
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Models using 3D cell culture techniques are increasingly accepted as the most biofidelic in vitro representations of tissues for research. These models are generated using biomatrices and bulk populations of cells derived from tissues or cel
Externí odkaz:
https://doaj.org/article/b79e8c355aa34c89ab658a1182d4d1eb
Autor:
Yingwen Hu, Danyang Chen, John V. Napoleon, Madduri Srinivasarao, Sunil Singhal, Cagri A. Savran, Philip S. Low
Publikováno v:
Scientific reports. 12(1)
Retrieval of circulating tumor cells (CTC) has proven valuable for assessing a patient's cancer burden, evaluating response to therapy, and analyzing which drug might treat a cancer best. Although most isolation methods retrieve CTCs based on size, s
Autor:
Rita Nanda, Claudine Isaacs, Bradley A. Hancock, Reshma Mahtani, Carla I. Falkson, Casey Bales, Michael A. Thompson, Kathy D. Miller, Maureen Cooper, Anna Maria Storniolo, Lee A. Albacker, Bryan P. Schneider, Tarah J. Ballinger, Marcelo Blaya, Guanglong Jiang, Yuan Zhong, Milan Radovich, Elisavet Paplomata, Chun Li Chang, Dean Pavlick, Sunil Badve, Erica Cantor, Christopher R. Chitambar, Yu-Hsiang Chen, Robert Graham, Cagri A. Savran, Jeffrey P. Solzak, Karen Daily, Radhika Walling, Christopher Gallagher, Filipa Lynce, Jeffrey P. Gregg, Fei Shen
Publikováno v:
JAMA oncology. 6(9)
Importance A significant proportion of patients with early-stage triple-negative breast cancer (TNBC) are treated with neoadjuvant chemotherapy. Sequencing of circulating tumor DNA (ctDNA) after surgery, along with enumeration of circulating tumor ce
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229949 (2020)
PLoS ONE
PLoS ONE
We present a two-tiered microchip system to capture and retrieve rare cells from blood samples with high purity. The first module of the system is a high throughput microfluidic interface that is used to immunomagnetically isolate targeted rare cells
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Models using 3D cell culture techniques are increasingly accepted as the most biofidelic in vitro representations of tissues for research. These models are generated using biomatrices and bulk populations of cells derived from tissues or cell lines.
Autor:
Timothy L. Ratliff, Roberto Pili, Norman D. Brault, Shadia I. Jalal, Zhe Wang, Cagri A. Savran, Philip S. Low, Onur Gur, Chun Li Chang, Wanfeng Huang
Publikováno v:
Lab on a Chip. 17:415-428
Current efforts for the detection of prostate cancer using only prostate specific antigen are not ideal and indicate a need to develop new assays - using multiple targets - that can more accurately stratify disease states. We previously introduced a
Autor:
Jeffrey P. Solzak, Yu-Hsiang Chen, Casey L. Bales, Yuan Zhong, M Radovich, Emily M. Nelson, Chun-Li Chang, Bradley A. Hancock, Cagri A. Savran
Publikováno v:
Cancer Research. 80:P4-01
Introduction: Circulating tumor cells (CTCs) represent a potent opportunity to glean important information about in vivo breast cancer biology using a non-invasive technique. However, EpCAM-based techniques are significantly limited by the presence o
Publikováno v:
Methods in Molecular Biology ISBN: 9781493985548
Bacteriophage phi29 DNA packaging motor consists of a dodecameric portal channel protein complex termed connector that allows transportation of genomic dsDNA and a hexameric packaging RNA (pRNA) ring to gear the motor. The elegant design of the porta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe083824b1b38c91038dbfd1461dad2
https://doi.org/10.1007/978-1-4939-8556-2_21
https://doi.org/10.1007/978-1-4939-8556-2_21
Autor:
Daniela Matei, Wanfeng Huang, Shadia I. Jalal, Bin-Da Chan, Cagri A. Savran, Philip S. Low, Chun Li Chang
Publikováno v:
Analytical Chemistry. 87:10205-10212
We report a detection system for simultaneous measurement of cellular and molecular markers of cancer. Magnetic beads conjugated with antibodies against a specific antigen are used to capture both free molecules and whole cells overexpressing the ant