Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cagla Ak"'
Autor:
Adelheid Cerwenka, Jochen Utikal, Viktor Umansky, Carolina De La Torre, Feyza Gül Özbay Kurt, Beatrice-Ana Cicortas, Bianca M Balzasch, Volker Ast, Ece Tavukcuoglu, Cagla Ak, Sebastian A Wohlfeil
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background Immunotherapies for malignant melanoma are challenged by the resistance developed in a significant proportion of patients. Myeloid-derived suppressor cells (MDSC), with their ability to inhibit antitumor T-cell responses, are a major contr
Externí odkaz:
https://doaj.org/article/35da36deda4a4f91b77a365a370aa2da
Autor:
Inga Menze, Jose Bernal, Pinar Kaya, Çağla Aki, Malte Pfister, Jonas Geisendörfer, Renat Yakupov, Roberto Duarte Coello, Maria d. C. Valdés-Hernández, Michael T. Heneka, Frederic Brosseron, Matthias C. Schmid, Wenzel Glanz, Enise I. Incesoy, Michaela Butryn, Ayda Rostamzadeh, Dix Meiberth, Oliver Peters, Lukas Preis, Dominik Lammerding, Daria Gref, Josef Priller, Eike J. Spruth, Slawek Altenstein, Andrea Lohse, Stefan Hetzer, Anja Schneider, Klaus Fliessbach, Okka Kimmich, Ina R. Vogt, Jens Wiltfang, Claudia Bartels, Björn H. Schott, Niels Hansen, Peter Dechent, Katharina Buerger, Daniel Janowitz, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H. Munk, Carolin Sanzenbacher, Petra Hinderer, Klaus Scheffler, Annika Spottke, Nina Roy-Kluth, Falk Lüsebrink, Katja Neumann, Joanna Wardlaw, Frank Jessen, Stefanie Schreiber, Emrah Düzel, Gabriel Ziegler
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Perivascular space (PVS) enlargement in ageing and Alzheimer’s disease (AD) and the drivers of such a structural change in humans require longitudinal investigation. Elucidating the effects of demographic factors, hypertension,
Externí odkaz:
https://doaj.org/article/63eb7743209c40979f7c3e0fd2e5303c
Autor:
Shivesh Ghura, Noah R. Beratan, Xinglong Shi, Elena Alvarez-Periel, Sarah E. Bond Newton, Cagla Akay-Espinoza, Kelly L. Jordan-Sciutto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Common single-nucleotide variants (SNVs) of eukaryotic translation initiation factor 2 alpha kinase 3 (EIF2AK3) slightly increase the risk of disorders in the periphery and the central nervous system. EIF2AK3 encodes protein kinase RNA-like
Externí odkaz:
https://doaj.org/article/cd849f67507748ea9342ece45a821b3e
Autor:
Emma LaNoce, Daniel Y. Zhang, Alan Garcia-Epelboim, Yijing Su, Yusha Sun, Giana Alepa, Angelina R. Angelucci, Cagla Akay-Espinoza, Kelly L. Jordan-Sciutto, Hongjun Song, Guo-li Ming, Kimberly M. Christian
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionFor many therapeutic drugs, including antiretroviral drugs used to treat people living with HIV-1 (PLWH), we have little data on the potential effects on the developing human brain due to limited access to tissue and historical constraint
Externí odkaz:
https://doaj.org/article/474d3437c0cf49128cbae36e4c3182d6
Publikováno v:
Viruses, Vol 16, Iss 8, p 1215 (2024)
Adeno-associated viruses (AAVs) are small, non-enveloped viruses that package a single-stranded (ss)DNA genome of 4.7 kilobases (kb) within their T = 1 icosahedral capsid. AAVs are replication-deficient viruses that require a helper virus to complete
Externí odkaz:
https://doaj.org/article/4d17873321fe477595257e1a38f3f611
Autor:
Kafait U. Malik, Bahar Tunçtan, Nehir Sucu, Özden Vezir, Sefika Pınar Şenol, Demet Sinem Güden, Meryem Temiz Reşitoğlu, Çağla Akıncı Uysal, Seyhan Fırat
Publikováno v:
Cukurova Medical Journal, Vol 47, Iss 1, Pp 219-232 (2022)
Purpose: We have previously demonstrated that activation of the mammalian target of rapamycin (mTOR)/inhibitory-κB-α/nuclear factor-κB p65 signaling pathway mediates organ injuries through increased oxidative/nitrosative stress and inflammatory re
Externí odkaz:
https://doaj.org/article/00140d3f95374da5beaa199e3cf88b84
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Adeno-associated virus (AAV) belongs to the Dependoparvovirus genus of the Parvoviridae family. AAV replication relies on a helper virus, such as adenovirus (Ad). Co-infection of AAV and Ad induces a DNA damage response (DDR), although its f
Externí odkaz:
https://doaj.org/article/c4395243fd8549ceb40b6a15bdb9c53a
Autor:
Ramazan Akdemir, İbrahim Kocayiğit, Yusuf Can, Harun Kılıç, Salih Şahinkuş, Emre Eynel, Çağla Akçay, Muhammed Aksoy, Ercan Aydın
Publikováno v:
Sakarya Tıp Dergisi, Vol 10, Iss 2, Pp 197-204 (2020)
Amaç: Primer perkutan koroner girişim (pPKG), ST elevasyonlu miyokard infarktüsünde (STEMI) ölüm başta olmak üzere klinik sonuçları fibrinolitik tedaviye kıyasla daha iyi olması üzerine, önerilen ve gittikçe daha yaygın kullanılan te
Externí odkaz:
https://doaj.org/article/cdc292111c80441b8db4ee65d5b299f8
Publikováno v:
Medicine Science, Vol 9, Iss 1, Pp 281-3 (2020)
Takotsubo cardiomyopathy (TCM) is a clinical entity resembling acute myocardial infarction that develops due to catecholamine discharge and coronary artery spasm following acute stress in postmenopausal women. The most common symptoms are chest pain,
Externí odkaz:
https://doaj.org/article/ae543ab05cd546a498549b9cbceb3fb7
Publikováno v:
Uludağ University Journal of The Faculty of Engineering, Vol 24, Iss 2, Pp 405-418 (2019)
Bu çalışmada Cr(III)’ün tavuk yumurtası kabuklarına adsorpsiyonu araştırılmıştır. Bu amaçla kalsine edilmiş (900°C ve 3 saat) ve doğal yumurta kabukları adsorplayıcı olarak kullanılmıştır. Yumurta kabuğu miktarı (0,6-2,0 g/
Externí odkaz:
https://doaj.org/article/40cf327280424b48ac25b1d4c18ac760