Zobrazeno 1 - 10
of 7 545
pro vyhledávání: '"Cag A"'
Publikováno v:
Vestnik Urologii, Vol 12, Iss 4, Pp 14-22 (2024)
Introduction. The influence of the length of the number of CAG repeats in the androgen receptor gene (nCAG AR) on endothelial dysfunction (EnD) is currently understudied.Objective. The study aimed to evaluate the relationship between the nCAG AR and
Externí odkaz:
https://doaj.org/article/af29a1df1a674340a5228cb8e9d4212a
Autor:
Purba Basu, Supriyo Choudhury, Siddhartha Sankar Mondal, Ummatul Siddique, Simin Rahman, Jacky Ganguly, Soumava Mukherjee, Nilam Singh, Mona Tiwari, Hrishikesh Kumar
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionSpinocerebellar ataxia type 12 (SCA12) is a rare autosomal dominant neurodegenerative disorder caused by abnormal CAG repeat expansion in the PPP2R2B gene. This disease is classically characterized by action tremor, dysarthria, ataxia, an
Externí odkaz:
https://doaj.org/article/4b8af0c17b2f4875b06be720f5827d91
Autor:
Ling Ou, Yajie Hao, Hengrui Liu, Zhixiang Zhu, Qingwei Li, Qingchang Chen, Ruixia Wei, Zhong Feng, Guimin Zhang, Meicun Yao
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundTerminalia chebula Retz, known as the King of Tibet, is considered a functional food in China, celebrated for its antioxidant, immune-modulating, antibacterial, and anti-inflammatory properties. Chebulinic acid, derived from aqueous extract
Externí odkaz:
https://doaj.org/article/d14086ad958545c8b5b7add6285de56a
Autor:
Natalya V. Ponomareva, Sergey A. Klyushnikov, Natalia Abramycheva, Rodion N. Konovalov, Marina Krotenkova, Ekaterina Kolesnikova, Daria Malina, Gusel Urazgildeeva, Elena Kanavets, Andrey Mitrofanov, Vitaly Fokin, Evgeny Rogaev, Sergey N. Illarioshkin
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Externí odkaz:
https://doaj.org/article/a39be3539f344a7bab8f7489cbc44a98
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The treatment of elderly patients diagnosed with acute myeloid leukemia (AML) poses significant challenges. Currently, one promising strategy in therapeutic interventions for geriatric individuals revolves around the utilization of small molecule tar
Externí odkaz:
https://doaj.org/article/e950632b7ff24bc19420d680b7963834
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundAchieving the 95–95–95 targets require an efficient and innovative person-centered approach, specifically community-based differentiated service delivery (DSD), to improve access to human immunodeficiency virus (HIV) services and reduce
Externí odkaz:
https://doaj.org/article/a6a14b13b1b64271bba5288277dbabcf
Autor:
Doo Eun Choi, Jun Wan Shin, Sophia Zeng, Eun Pyo Hong, Jae-Hyun Jang, Jacob M Loupe, Vanessa C Wheeler, Hannah E Stutzman, Ben Kleinstiver, Jong-Min Lee
Publikováno v:
eLife, Vol 12 (2024)
An expanded CAG repeat in the huntingtin gene (HTT) causes Huntington’s disease (HD). Since the length of uninterrupted CAG repeat, not polyglutamine, determines the age-at-onset in HD, base editing strategies to convert CAG to CAA are anticipated
Externí odkaz:
https://doaj.org/article/be3156c656d24edfa4a721019c3ab21e
Autor:
Marwa A. Gouda, Sara A. Saied, Ahmed Edrees, Rasha Galal Mostafa, Ashraf Elfert, Aya Abdallah seleem, Asmaa Shams, Sameh Afify
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Toxoplasma gondii (T. gondii) and Helicobacter pylori (H. pylori) are among the most prevalent foodborne parasitic and bacterial infections worldwide. However, the concurrent impact of coinfection on gastric pathology has yet to b
Externí odkaz:
https://doaj.org/article/0dd6efe46e5b43bd875cdde621703097
Autor:
L. H. Van, V. T. Nguyen, T. T. T. Le, T. N. T. Thanh, L. V. T. Nghi, N. H. Van, V. T. Q. Huong, M. Chambers, N. T. T. Thuong
Publikováno v:
Public Health Action, Vol 14, Iss 1, Pp 7-13 (2024)
It is essential that communities at risk from TB are involved in TB research. Community advisory groups (CAGs) are one mechanism for involving communities in research and creating platforms for discussions between researchers and community members. W
Externí odkaz:
https://doaj.org/article/26f1041186ae489da1e389098434ca9b
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 28, Iss 1, Pp 80-89 (2024)
Androgens are required for stimulation and maintenance of skeletal growth and bone homeostasis. Physiological functions of androgens are mediated through the androgen receptor (AR). The androgen receptor gene AR has a polymorphic trinucleotide CAG re
Externí odkaz:
https://doaj.org/article/4a8168162d474f5a9b51eec68a3ac5a2