Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Caesar M. Hernandez"'
Autor:
Caesar M. Hernandez, Macy A. McCuiston, Kristian Davis, Yolanda Halls, Juan Pablo Carcamo Dal Zotto, Nateka L. Jackson, Lynn E. Dobrunz, Peter H. King, Lori L. McMahon
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 39, Iss , Pp 100798- (2024)
In addition to extracellular amyloid plaques, intracellular neurofibrillary tau tangles, and inflammation, cognitive and emotional affect perturbations are characteristic of Alzheimer's disease (AD). The cognitive and emotional domains impaired by AD
Externí odkaz:
https://doaj.org/article/504715aab0ea482fa47c628f92a6648d
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2024)
The glucocorticoid (GC) hypothesis posits that effects of stress and dysregulated hypothalamic-pituitary-adrenal axis activity accumulate over the lifespan and contribute to impairment of neural function and cognition in advanced aging. The validity
Externí odkaz:
https://doaj.org/article/76ddd7d6ed274c9499e2d45771514323
Autor:
Abbi R. Hernandez, Caesar M. Hernandez, Leah M. Truckenbrod, Keila T. Campos, Joseph A. McQuail, Jennifer L. Bizon, Sara N. Burke
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
As the number of individuals living beyond the age of 65 is rapidly increasing, so is the need to develop strategies to combat the age-related cognitive decline that may threaten independent living. Although the link between altered neuronal signalin
Externí odkaz:
https://doaj.org/article/6cd992fccf6b49ed966f399ff7eb7819
Autor:
Abbi R. Hernandez, Caesar M. Hernandez, Keila Campos, Leah Truckenbrod, Quinten Federico, Brianna Moon, Joseph A. McQuail, Andrew P. Maurer, Jennifer L. Bizon, Sara N. Burke
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Age-related cognitive decline has been linked to a diverse set of neurobiological mechanisms, including bidirectional changes in proteins critical for neuron function. Importantly, these alterations are not uniform across the brain. For example, the
Externí odkaz:
https://doaj.org/article/08bc3b5720464ec78f4c79e5b2562d99
Autor:
Peter H. King, Jessica M. Hoffman, Christy S. Carter, Sara N. Burke, Thomas W. Buford, Jennifer L. Bizon, Caesar M Hernandez, Abigail R. Hernandez, Lori L. McMahon
Publikováno v:
J Gerontol A Biol Sci Med Sci
Neuroscience has a rich history of studies focusing on neurobiology of aging. However, much of the aging studies in neuroscience occur outside of the gerosciences. The goal of this primer is 2-fold: first, to briefly highlight some of the history of
Autor:
Adriaan W. Bruijnzeel, Marcelo Febo, Caitlin A. Orsini, Jennifer L. Bizon, Caesar M Hernandez, Shelby L Blaes, Barry Setlow
Publikováno v:
J Psychopharmacol
Background: Cannabis (marijuana) is the most widely used illicit drug in the USA, and consumption among adolescents is rising. Some animal studies show that adolescent exposure to delta 9-tetrahydrocannabinol or synthetic cannabinoid receptor 1 agoni
Fear-based disorders such as posttraumatic stress disorder (PTSD) steepen age-related cognitive decline and doubles the risk for developing Alzheimer’s disease. Due to the seemingly hyperactive properties of fear memories, PTSD symptoms can worsen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ef98ef9830fd4a695f70b983972bf3
https://doi.org/10.1101/2022.03.12.484093
https://doi.org/10.1101/2022.03.12.484093
Autor:
Barry Setlow, Tyler W Ten Eyck, Sara M Betzhold, Alexa-Rae Wheeler, Jennifer L. Bizon, Hassan Perera, Shelby L Blaes, Caitlin A. Orsini, Caesar M Hernandez, Tyler S. Garman
Publikováno v:
Neuropsychopharmacology
Psychiatric diseases characterized by dysregulated risky decision making are differentially represented in males and females. The factors that govern such sex differences, however, remain poorly understood. Using a task in which rats make discrete tr
Autor:
Caesar M. Hernandez, Joseph A. McQuail, Tyler W. Ten Eyck, Alexa-Rae Wheeler, Chase C. Labiste, Barry Setlow, Jennifer L. Bizon
Publikováno v:
Neuropharmacology
The ability to decide adaptively between immediate vs. delayed gratification (intertemporal choice) is critical for well-being and is associated with a range of factors that influence quality of life. In contrast to young adults, many older adults sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d6473fc39940b2ba8124e20bd4055b
https://europepmc.org/articles/PMC9297337/
https://europepmc.org/articles/PMC9297337/
Bridging the Gap: A Geroscience Primer for Neuroscientists With Potential Collaborative Applications
Autor:
Abbi R. Hernandez, Thomas W. Buford, Jessica M. Hoffman, Jennifer L. Bizon, Christy S. Carter, Caesar M Hernandez, Sara N. Burke
Publikováno v:
J Gerontol A Biol Sci Med Sci
While neurodegenerative diseases can strike at any age, the majority of afflicted individuals are diagnosed at older ages. Due to the important impact of age in disease diagnosis, the field of neuroscience could greatly benefit from the many of the t