Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cadapakam Venkatramani"'
Autor:
Joanna Korpanty, Karthikeyan Gnanasekaran, Cadapakam Venkatramani, Nanzhi Zang, Nathan C. Gianneschi
Publikováno v:
Cell Reports Physical Science, Vol 3, Iss 3, Pp 100772- (2022)
Summary: Direct imaging of the dynamics of polymeric assemblies in organic solvents is an outstanding challenge. Herein, we apply liquid cell transmission electron microscopy (LCTEM) to study polymeric nanomaterials in organic solvents. LCTEM is dist
Externí odkaz:
https://doaj.org/article/f9c5570b61c548629ca05368f871af4a
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 162:192-204
It is highly desirable to have a universal detector that can detect all types of compounds and give a uniform response regardless of the physiochemical properties of the compounds. With such a universal detector, all components in a sample can be acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c976340d70b9b59912298a10ece181f5
https://doi.org/10.1016/j.jpba.2018.09.029
https://doi.org/10.1016/j.jpba.2018.09.029
Autor:
Chun-Wan Yen, Lu Dai, Steven Chin, Brian Roper, Elizabeth S. Hecht, Chloe Hu, Cadapakam Venkatramani, Nisana Andersen, Robert Kuhn, Dennis Leung, Fiona Lin, Jason Gruenhagen, Christopher M. Crittenden, Alberto Estevez, Mohammad Al-Sayah, Amin Famili, Lance Cadang, Tao Chen, Shijia Tang, Cinzia Stella, Karthik Nagapudi, Peter Yehl, Richard Vandlen, Peter Liu, Alexis Rohou, Debby P. Chang, Rami N. Hannoush
Publikováno v:
Journal of Pharmaceutical Sciences.
Constrained peptides (CPs) have emerged as attractive candidates for drug discovery and development. To fully unlock the therapeutic potential of CPs, it is crucial to understand their physical stability and minimize the formation of aggregates that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e078389a18d4495af32516044ad50a61
https://doi.org/10.1016/j.xphs.2020.12.041
https://doi.org/10.1016/j.xphs.2020.12.041
Publikováno v:
Journal of Chromatography B. 1084:89-95
Enantioselective analysis is an essential requirement during the pharmaceutical development of chiral drug molecules. In pre-clinical and clinical studies, the Food and Drug Administration (FDA) mandates the assessment of “in vivo” inter-conversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf8afb9777370d39735268956fb2f09
https://doi.org/10.1016/j.jchromb.2018.03.029
https://doi.org/10.1016/j.jchromb.2018.03.029
Publikováno v:
Organic Process Research & Development. 21:182-186
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry which are known to be weakly mutagenic in microbial assays. In this paper, we describe an inductively coupled plasma mass spectrometer method (ICP-MS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2d0e72592f42445e31440af03a154cc
https://doi.org/10.1021/acs.oprd.6b00325
https://doi.org/10.1021/acs.oprd.6b00325
Autor:
Nik P. Chetwyn, Guannan Li, Mohammad Al-Sayah, Peter Yehl, Meenakshi Goel, Larry Wigman, James Girotti, Cadapakam Venkatramani, Lisa Zang
Publikováno v:
Talanta. 148:548-555
A new interface was designed to enable the coupling of reversed phase liquid chromatography (RPLC) and supercritical fluid chromatography (SFC). This online two-dimensional chromatographic system utilizing RPLC in the first dimension and SFC in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dadc98bc7319c92bd40422512ba277
https://doi.org/10.1016/j.talanta.2015.10.054
https://doi.org/10.1016/j.talanta.2015.10.054
Publikováno v:
Journal of chromatography. A. 1521
In this manuscript, the application of high-resolution sampling (HRS) two-dimensional liquid chromatography (2D-LC) in the detailed analysis of key linker drug intermediate is presented. Using HRS, selected regions of the primary column eluent were t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb913c1806e76ddc078b8b2da5b0e6e2
https://pubmed.ncbi.nlm.nih.gov/28942996
https://pubmed.ncbi.nlm.nih.gov/28942996
Publikováno v:
Journal of Separation Science. 37:3214-3225
Chromatographic analysis of trace organic impurities/degradants coeluting in the midst of active pharmaceutical ingredient can be challenging given similarities in their structures and differences in their relative levels/intensities. Conventional de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99d92e5baa6a8c17bea50cebf9e1c070
https://doi.org/10.1002/jssc.201400590
https://doi.org/10.1002/jssc.201400590
Autor:
Gregory Gallegos, Cadapakam Venkatramani, Minli Xie, King Chuang, Sueanne Lee, Xiling Song, Thirunellai Venkateshwaran, Yong Cui
Publikováno v:
Journal of Pharmaceutical Sciences. 101:4597-4607
Multivariate data analysis methods such as partial least square (PLS) modeling have been increasingly applied to pharmaceutical product development. This study applied the PLS modeling to analyze a product development dataset generated from a design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572dd7c5d30436b6dc2b2c4ce4f8c851
https://doi.org/10.1002/jps.23322
https://doi.org/10.1002/jps.23322
Publikováno v:
Journal of Separation Science. 35:1748-1754
In general, chromatographic analysis of chiral compounds involves a minimum of two methods; a primary achiral method for assay and impurity analysis and a secondary chiral method for assessing chiral purity. Achiral method resolves main enantiomeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c1b244a75c3350980c09691e3bba324
https://doi.org/10.1002/jssc.201200005
https://doi.org/10.1002/jssc.201200005